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Anorexia and bulimia

Anorexia and bulimia may be autoimmune diseases—and so may several other psychiatric illnesses

Psychiatric disorders and immunity
Molecular self-loathing
Sep 29th 2005
From The Economist print edition

(subscription site, abstract only)

Study referred to is here:

http://www.pnas.org/content/102/41/14865.full

Evidence of infectious cause

Sample PubMed cite1

Keywords: ,

Notes and comments

===== Symptoms ===== ===== Management ===== ===== Other treatments ===== ===== Tests ===== ===== Diagnosis ===== ===== Epidemiology ===== ===== Types ===== ===== Evidence of infectious cause===== ===== Role of vitamin D metabolism ===== ===== Politics ===== ===== Patient interviews ===== ===== Presentations and publications=====

Review provides new insights into the causes of anorexia New imaging technology provides insight into abnormalities in the brain circuitry of patients with anorexia nervosa (commonly known as anorexia) that may contribute to the puzzling symptoms found in people with the eating disorder.

I haven't researched this area in depth but this paper, which found an increase in methanogens in anorexics, appears to be the one people cite again and again. http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007125

I'm not sure I can completely tease out the significance of this study, but this sort of result suggests that famine may affect the microbiome in a lasting way: http://www.ncbi.nlm.nih.gov/pubmed/14696131

Final point: IMO, we should all be careful not to define the chain of events. What if a disruption in the microbiome preceded anorexia and the anorexia “phenotype” was only expressed in certain cultures?

References

1. Marshall TG Vitamin D discovery outpaces FDA decision making. Bioessays. 2008;30:173-82.
Last modified: 01.02.2012
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