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Bactrim DS (co-trimoxazole)

Bactrim DS is an antibiotic used by patients on the Marshall ProtocolA curative medical treatment for chronic inflammatory disease. Based on the Marshall Pathogenesis. (MP). Bactrim is a combination of two antibiotics, trimethoprim and sulfamethoxazole. This antibiotic combination is thought to work synergistically by inhibiting several steps in the process by which bacteria synthesize folate for their use.

Bactrim DS is the brand name. It is also known as Septra, Sulfatrim, Cotrim, Novo-Trimel, Nu-Cotrimox, Resprim, Roubac and Septrin. The generic name is co-trimoxazole.

Bactrim DS has a reputation for targeting the bacteria in the gastrointestinal tract. Either generic or brand name is appropriate to use.

Dosing and administration

Related article: Dividing medications

Bactrim comes in DS (Double Strength 800/160mg) or RS (Regular Strength 400/80mg). Regular strength is a combination of 400mg of sulfamethoxazole and 80mg of trimethoprim.

The minimum dose of Bactrim DS is 125mg and the maximum dose is 1000mg.

Allergies to sulfa medications?

Many patients with Th1 inflammationThe complex biological response of vascular tissues to harmful stimuli such as pathogens or damaged cells. It is a protective attempt by the organism to remove the injurious stimuli as well as initiate the healing process for the tissue. have been told that they are allergic to sulfa preparations. This “allergic” reaction experienced in the past was most likely an immunopathological reactionA temporary increase in disease symptoms experiences by Marshall Protocol patients that results from the release of cytokines and endotoxins as disease-causing bacteria are killed..

These patients should begin with 1/4 tablet (or less) of regular strength Bactrim and ramp up by 1/4 increments every two weeks (or as symptoms allow) to a full tablet. Then, they should progress to Bactrim DS. Cutaneous reactions such as pruritus and rash are common and may be treated palliatively.

A complete blood count (CBC) with differential will help identify those very few patients who may develop a rapid drop in red blood cells (RBC), which would require lowering of the Bactrim dosage.

Combining Bactrim with other Marshall Protocol antibiotics

Bactrim is taken every other day with the dose of minocyclineBacteriostatic antibiotic used by Marshall Protocol patients./demeclocyclineBacteriostatic antibiotic used by patients on the Marshall Protocol..

In later stages of the treatments, Bactrim DS may be combined with other MP antibiotics in the following fashion:

Typical targets for immunopathology

Bactrim is sometimes prescribed for the non-MP application of traveler's diarrhea. Patients on the MP have reported stronger gastrointestinal immunopathologyA temporary increase in disease symptoms experienced by Marshall Protocol patients that results from the release of cytokines and endotoxins as disease-causing bacteria are killed. (IP) when taking Bactrim. Other commonly reported IP include increased fatigue and skin symptoms.

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Last modified: 06.20.2010
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