The over-exuberant Stage-Five immune response

anonymous@undisclosed.example.com (Anonymous) — Wed, 14 Sep 2022 20:53:53 +0000

10.13.2018		current
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-	<blockquote>Very few have experienced any problems with Stage Five. I think it mainly gives trouble when pathogens other than the Th1 pathogens are present, and have escaped the antibiotics. I got hit when the fibrosis in my lungs began to remodel, but I doubt that anybody else in the cohort was afflicted with fibrotic tissue [[http://sarcinfo.com/xrays\|as badly as I]]. Additionally, I hadn't been exercising (at all) during my recovery, so the remodelling began quite suddenly. On the other hand, the other early adopters have not had identifiable problems. We put out the documentation partly over an abundance of caution, and partly because we had to change the model to account for this (unexpected) glitch in recovery trajectory.	+	<blockquote>Very few have experienced any problems with Stage Five. I think it mainly gives trouble when pathogens other than the Th1 pathogens are present, and have escaped the antibiotics. I got hit when the fibrosis in my lungs began to remodel, but I doubt that anybody else in the cohort was afflicted with fibrotic tissue [[https://sarcinfo.com/xrays\|as badly as I]]. Additionally, I hadn't been exercising (at all) during my recovery, so the remodelling began quite suddenly. On the other hand, the other early adopters have not had identifiable problems. We put out the documentation partly over an abundance of caution, and partly because we had to change the model to account for this (unexpected) glitch in recovery trajectory.

	Unless your X-rays show the degree of damage which mine did, you should be fine with a very nominal amount of exercise. Do not do anything which tires you out. Walking around the neighborhood in the late evenings is probably a good choice (depending on your neighborhood, of course).		Unless your X-rays show the degree of damage which mine did, you should be fine with a very nominal amount of exercise. Do not do anything which tires you out. Walking around the neighborhood in the late evenings is probably a good choice (depending on your neighborhood, of course).
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	When a patient's symptoms surge after an extended period on the MP, the initial strategy is to		When a patient's symptoms surge after an extended period on the MP, the initial strategy is to
-	discontinue azithromycin if it has been taken. //N.B. the use of azithromycin is now strongly discouraged//. This will often result in a one-time exacerbation of symptoms, particularly from days 10 to 12 (and possibly even for some weeks), as the concentration of the azithromycin slowly wanes, but in the long run will lead to greater stability.	+	discontinue azithromycin if it has been taken. //N.B. the use of azithromycin is now strongly discouraged//.
		+
		+	This will often result in a one-time exacerbation of symptoms, particularly from days 10 to 12 (and possibly even for some weeks), as the concentration of the azithromycin slowly wanes, but in the long run will lead to greater stability.

	Progressively withdrawing minocycline and clindamycin, while modulating olmesartan, should keep		Progressively withdrawing minocycline and clindamycin, while modulating olmesartan, should keep
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	causing too much immunopathology, it is necessary to stop them. For many members, indeed, ABx are used only to provoke IP when it has dwindled.		causing too much immunopathology, it is necessary to stop them. For many members, indeed, ABx are used only to provoke IP when it has dwindled.

-	Please ask for moderator assistance on the [[http://marshallprotocol.com\|MarshallProtocol.com]] study site before antibiotic use is modified. We are happy to assist you in any way we can.	+	Please ask for moderator assistance on the [[https://marshallprotocol.com\|MarshallProtocol.com]] study site before antibiotic use is modified. We are happy to assist you in any way we can.


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	===== Read more =====		===== Read more =====

-	* [[http://autoimmunityresearch.org/VDR-Time-Benicar.pdf\|Visual description of all stages of recovery]]	+	* [[https://autoimmunityresearch.org/VDR-Time-Benicar.pdf\|Visual description of all stages of recovery]]


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		+	<nodisp>
	===== Notes and comments =====		===== Notes and comments =====

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	*		*

-	http://autoimmunityresearch.org/VDR-Time-Benicar.pdf	+	https://autoimmunityresearch.org/VDR-Time-Benicar.pdf

-	http://autoimmunityresearch.org/stage5.pdf	+	https://autoimmunityresearch.org/stage5.pdf

	* There's confusion among members re stage 5, leading to fear of it from early in their MP journey. This page swings from painting a fearful picture of unrestrainable immune reaction to assurances that only some of the most ill experience this. It's self-contradictory as to whether the term 'stage 5' refers to anyone who continues to herx without abx, or only to those whose immune system is 'over-exuberant'. --- //Julia 2009/01/31 05:20//		* There's confusion among members re stage 5, leading to fear of it from early in their MP journey. This page swings from painting a fearful picture of unrestrainable immune reaction to assurances that only some of the most ill experience this. It's self-contradictory as to whether the term 'stage 5' refers to anyone who continues to herx without abx, or only to those whose immune system is 'over-exuberant'. --- //Julia 2009/01/31 05:20//
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	* IMO, Stage 5 should refer to everyone who continues to herx without abx - i.e. their own immune system is functioning properly. Then there could be a warning that a few people have had this runaway reaction, while many are having a much more gentle stage 5. --- //Julia 2009/02/04 17:51//		* IMO, Stage 5 should refer to everyone who continues to herx without abx - i.e. their own immune system is functioning properly. Then there could be a warning that a few people have had this runaway reaction, while many are having a much more gentle stage 5. --- //Julia 2009/02/04 17:51//

-	===== References =====	+	===== References =====</nodisp>

Marshall Protocol Knowledge Base - home:mp:stages

The over-exuberant Stage-Five immune response