Marshall Protocol Knowledge Base - home:symptoms:neurological

Cognitive dysfunction (brain fog)

anonymous@undisclosed.example.com (Anonymous) — Wed, 14 Sep 2022 20:53:53 +0000

05.29.2020		current
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	Cognitive dysfunction (also known as brain fog) is the loss of intellectual functions such as thinking, remembering, and reasoning of sufficient severity to interfere with daily functioning. Patients with cognitive dysfunction have trouble with verbal recall, basic arithmetic, and concentration.		Cognitive dysfunction (also known as brain fog) is the loss of intellectual functions such as thinking, remembering, and reasoning of sufficient severity to interfere with daily functioning. Patients with cognitive dysfunction have trouble with verbal recall, basic arithmetic, and concentration.

-	According to the Marshall Pathogenesis, cognitive dysfunction is caused by microbes. More severe forms of cognitive dysfunction are seen in diseases such as Alzheimer's, diseases for which there is strong evidence of a bacterial etiology. Often associated with chronic fatigue syndrome,(({{pubmed>long:17605583}})) cognitive dysfunction is also seen in patients with multiple sclerosis,(({{pubmed>long:16847772}})) depression,(({{pubmed>long:17605583}})) fibromyalgia,(({{pubmed>long:11286668}})) and dozens of others diseases.	+	According to the Marshall Pathogenesis, cognitive dysfunction is caused by microbes. More severe forms of cognitive dysfunction are seen in diseases such as Alzheimer's, diseases for which there is strong evidence of a bacterial etiology. Often associated with chronic fatigue syndrome,(({{pmid>long:17605583}})) cognitive dysfunction is also seen in patients with multiple sclerosis,(({{pmid>long:16847772}})) depression,(({{pmid>long:17605583}})) fibromyalgia,(({{pmid>long:11286668}})) and dozens of others diseases.


	Like all symptoms of inflammatory disease, cognitive dysfunction may temporarily increase during periods of immunopathology. Cognitive dysfunction can be managed using the [[home:mp:managing_immunopathology\|generic strategies for managing immunopathology]], and should resolve over the course of the Marshall Protocol (MP).		Like all symptoms of inflammatory disease, cognitive dysfunction may temporarily increase during periods of immunopathology. Cognitive dysfunction can be managed using the [[home:mp:managing_immunopathology\|generic strategies for managing immunopathology]], and should resolve over the course of the Marshall Protocol (MP).

-	Some studies seem to suggest that sick women experience cognitive dysfunction more frequently and more severely than their male counterparts.(({{pubmed>long:19558254}})) (({{pubmed>long:14529997}}))	+	Some studies seem to suggest that sick women experience cognitive dysfunction more frequently and more severely than their male counterparts.(({{pmid>long:19558254}})) (({{pmid>long:14529997}}))

	===== Management of symptoms =====		===== Management of symptoms =====
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-	* cognitive and functional decline often follow severe sepsis – The researchers focused their attention on 516 individuals who survived hospitalization for severe sepsis and 4517 who survived a nonsepsis hospitalization. The average age of survivors at hospitalization was 76.9 years. Following severe sepsis hospitalization, but not nonsepsis general hospitalization, there was a significant increase in the odds of developing both cognitive and physical dysfunction that persisted throughout the 8-year follow-up period, the researchers report.(({{pubmed>long:20978262}}))	+	* cognitive and functional decline often follow severe sepsis – The researchers focused their attention on 516 individuals who survived hospitalization for severe sepsis and 4517 who survived a nonsepsis hospitalization. The average age of survivors at hospitalization was 76.9 years. Following severe sepsis hospitalization, but not nonsepsis general hospitalization, there was a significant increase in the odds of developing both cognitive and physical dysfunction that persisted throughout the 8-year follow-up period, the researchers report.(({{pmid>long:20978262}}))
-	* aging immune cells in animal models – The decline in brain function associated with disease and old age could be due to the decline in the function of immune cells, which is likely caused by infection. As described in New Scientist, prompted by studies suggesting immune responses can help repair the nervous system, Jonathan Kipnis and colleagues at the University of Virginia created mice that lack CD4 cells, a kind of T-cell. They found the mice performed extremely poorly in tasks involving learning and memory, but when they were injected with CD4 cells from healthy mice, their memories improved.(({{pubmed>long:15141078}})) Similarly, when he killed CD4 cells in healthy mice, their memory declined. Further animal studies by Kipnis and others show that learning new tasks triggers a mild stress response within the brain, which prompts CD4 cells to rally to the meninges, the membranes that surround the brain. Here, they release IL-4, which both switches off the stress response and tells brain cells called astrocytes to release brain-derived neurotrophic factor, a protein that enhances learning.(({{pubmed>long:20439540}})) Whether these animal studies are relevant to human learning and memory remains unclear, but there is some indirect evidence to support it. For example, many chemotherapy drugs suppress the immune system, which might explain why some people with cancer develop "chemobrain" - a term used to describe the cognitive problems and memory loss associated with chemotherapy. Sluggish immune cells might also explain why our brains slow down as we age. "The number one cell affected by ageing is the T-cell," says Kipnis. "I'm not saying it's the only factor leading to age-related dementia, but it could definitely be one of them."	+	* aging immune cells in animal models – The decline in brain function associated with disease and old age could be due to the decline in the function of immune cells, which is likely caused by infection. As described in New Scientist, prompted by studies suggesting immune responses can help repair the nervous system, Jonathan Kipnis and colleagues at the University of Virginia created mice that lack CD4 cells, a kind of T-cell. They found the mice performed extremely poorly in tasks involving learning and memory, but when they were injected with CD4 cells from healthy mice, their memories improved.(({{pmid>long:15141078}})) Similarly, when he killed CD4 cells in healthy mice, their memory declined. Further animal studies by Kipnis and others show that learning new tasks triggers a mild stress response within the brain, which prompts CD4 cells to rally to the meninges, the membranes that surround the brain. Here, they release IL-4, which both switches off the stress response and tells brain cells called astrocytes to release brain-derived neurotrophic factor, a protein that enhances learning.(({{pmid>long:20439540}})) Whether these animal studies are relevant to human learning and memory remains unclear, but there is some indirect evidence to support it. For example, many chemotherapy drugs suppress the immune system, which might explain why some people with cancer develop "chemobrain" - a term used to describe the cognitive problems and memory loss associated with chemotherapy. Sluggish immune cells might also explain why our brains slow down as we age. "The number one cell affected by ageing is the T-cell," says Kipnis. "I'm not saying it's the only factor leading to age-related dementia, but it could definitely be one of them."


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	{{tag>diseases managing symptoms neurological}}		{{tag>diseases managing symptoms neurological}}

		+	<nodisp>
	===== Notes and comments =====		===== Notes and comments =====

	broken links		broken links
-	[[http://bacteriality.com/2008/03/09/cognitive-dysfunction/\|Cognitive dysfunction in women with chronic disease: a summary of my upcoming presentation at the 2008 Days of Molecular Medicine conference]]	+	[[https://bacteriality.com/2008/03/09/cognitive-dysfunction/\|Cognitive dysfunction in women with chronic disease: a summary of my upcoming presentation at the 2008 Days of Molecular Medicine conference]]

		+	* [[https://bacteriality.com/category/cognitive-dysfunction/\|Cognitive dysfunction]]
		+	{{:home:bacteriality.gif\|https://bacteriality.com/2007/10/28/interview6}}

-	[[http://www.newscientist.com/article/dn19952-infectious-moods-tcell-recall.html\|New Scientist]]	+	[[https://www.newscientist.com/article/dn19952-infectious-moods-tcell-recall.html\|New Scientist]]
	As described in New Scientist, prompted by studies suggesting immune responses can help repair the nervous system, Jonathan Kipnis and colleagues at the University of Virginia created mice that lack CD4 cells, a kind of T-cell.		As described in New Scientist, prompted by studies suggesting immune responses can help repair the nervous system, Jonathan Kipnis and colleagues at the University of Virginia created mice that lack CD4 cells, a kind of T-cell.
	* Legacy content		* Legacy content
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-	[[http://www.medscape.com/viewarticle/731212\|Cognitive and Functional Decline Often Follow Severe Sepsis]]	+	[[https://www.medscape.com/viewarticle/731212\|Cognitive and Functional Decline Often Follow Severe Sepsis]]
		+
		+	===== References =====</nodisp>

-	===== References =====

Fatigue

anonymous@undisclosed.example.com (Anonymous) — Wed, 14 Sep 2022 20:53:53 +0000

01.18.2020		current
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-	<relatedarticles> [[home:diseases:anemia\|Anemia]], [[home:diseases:cfs\|Chronic fatigue syndrome]], [[home:othertreatments:othertreatments\|Thyroid hormone and mineral supplementation]]</article>	+	<relatedarticles> [[home:diseases:anemia\|Anemia]], [[home:diseases:cfs\|Chronic fatigue syndrome]], [[home:othertreatments:thyroid_hormones#research\|Thyroid hormone and mineral supplementation]]</article>


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	===== Inflammation causes fatigue =====		===== Inflammation causes fatigue =====

-	The hallmark of chronic diseases is inflammation, the body's response to infection. Inflammation plays an increasingly well-defined role in fatigue.(({{pubmed>long:18793712}}))	+	The hallmark of chronic diseases is inflammation, the body's response to infection. Inflammation plays an increasingly well-defined role in fatigue.(({{pmid>long:18793712}}))

-	For example, most researchers believe that the fatigue so common in patients with multiple sclerosis, a typical Th1 disease, is caused by inflammatory cytokines such as TNF-alpha and interferon gamma that go along with elevated 1,25-D. One study found that TNF-alpha values significantly correlated with daytime sleepiness as measured by the Epworth Sleepiness Scale. Controlling for disease activity (as measured by the Cambridge Multiple Sclerosis Basic Score), disease duration, Expanded Disability Status Scale, and depression further increased the correlation of cytokine production and fatigue.(({{pubmed>long:16361589}}))	+	For example, most researchers believe that the fatigue so common in patients with multiple sclerosis, a typical Th1 disease, is caused by inflammatory cytokines such as TNF-alpha and interferon gamma that go along with elevated 1,25-D. One study found that TNF-alpha values significantly correlated with daytime sleepiness as measured by the Epworth Sleepiness Scale. Controlling for disease activity (as measured by the Cambridge Multiple Sclerosis Basic Score), disease duration, Expanded Disability Status Scale, and depression further increased the correlation of cytokine production and fatigue.(({{pmid>long:16361589}}))


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	==== Virtues of fatigue =====		==== Virtues of fatigue =====

-	From an evolutionary perspectives, the fatigue caused by inflammation may benefit a person. Andrew Miller of Emory University School of Medicine states in [[http://www.newscientist.com/article/dn19953-infectious-moods-a-depressing-side-effect.html\|New Scientist]] that "cytokines are trying to shut your body down so that you can devote your resources to healing." In a 2009 paper, he goes on to conclude that fatigue is part of healing:	+	From an evolutionary perspectives, the fatigue caused by inflammation may benefit a person. Andrew Miller of Emory University School of Medicine states in [[https://www.newscientist.com/article/dn19953-infectious-moods-a-depressing-side-effect.html\|New Scientist]] that "cytokines are trying to shut your body down so that you can devote your resources to healing." In a 2009 paper, he goes on to conclude that fatigue is part of healing:

	<blockquote>Taken together, these effects of cytokines on the brain and behavior appear to subserve competing evolutionary survival priorities that promote reduced activity to allow healing, and hypervigilance to protect against future attack.		<blockquote>Taken together, these effects of cytokines on the brain and behavior appear to subserve competing evolutionary survival priorities that promote reduced activity to allow healing, and hypervigilance to protect against future attack.
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-	Increased energy consumption by immune cells requires a metabolic adaptation of the whole organism. (({{pubmed>long:26427038}}))	+	Increased energy consumption by immune cells requires a metabolic adaptation of the whole organism. (({{pmid>long:26427038}}))

	* Develop an "energy conservation" program – Re-define "necessary" and sort out the really important activities from those that can wait. MP patients should pace themselves through the day, saving necessary activities for the time of day when they tend to have more energy. Forego jobs that need not be done every day, such as making beds.		* Develop an "energy conservation" program – Re-define "necessary" and sort out the really important activities from those that can wait. MP patients should pace themselves through the day, saving necessary activities for the time of day when they tend to have more energy. Forego jobs that need not be done every day, such as making beds.
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	In the management of fatigue, [[home:othertreatments:stimulants\|stimulants]] such as modafinil (Provigil) and caffeine are not recommended. There is limited data on how exactly stimulants modulate the immune response.		In the management of fatigue, [[home:othertreatments:stimulants\|stimulants]] such as modafinil (Provigil) and caffeine are not recommended. There is limited data on how exactly stimulants modulate the immune response.

-	Caffeine ingestion can delay fatigue during exercise, but the mechanisms remain elusive. (({{pubmed>long:12399249}}))	+	Caffeine ingestion can delay fatigue during exercise, but the mechanisms remain elusive. (({{pmid>long:12399249}}))


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	{{tag>managing symptoms}}		{{tag>managing symptoms}}

		+	<nodisp>
	===== Notes and comments =====		===== Notes and comments =====

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-	===== References =====	+	===== References =====</nodisp>

Headaches and migraines

anonymous@undisclosed.example.com (Anonymous) — Wed, 14 Sep 2022 20:53:53 +0000

05.29.2020		current
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-	Different researchers have successfully used ARBs – of which olmesartan (Benicar) is one – to treat migraines and headaches.(({{pubmed>long:12681087}}))(({{pubmed>long:12503978}})) For patients on the Marshall Protocol (MP), the institution of the olmesartan (Benicar) blockade is enough to resolve migraines.	+	Different researchers have successfully used ARBs – of which olmesartan (Benicar) is one – to treat migraines and headaches.(({{pmid>long:12681087}}))(({{pmid>long:12503978}})) For patients on the Marshall Protocol (MP), the institution of the olmesartan (Benicar) blockade is enough to resolve migraines.
	===== Management of symptoms =====		===== Management of symptoms =====

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	//~Knochen//</blockquote>		//~Knochen//</blockquote>

-	//N.B. the above recorded interviews are no longer available online//	+


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		+	<nodisp>
	===== Notes and comments =====		===== Notes and comments =====


	* Legacy content		* Legacy content
-	* http://www.marshallprotocol.com/view_topic.php?id=4446&forum_id=37&jump_to=65795#p65795 s100	+	* https://www.marshallprotocol.com/view_topic.php?id=4446&forum_id=37&jump_to=65795#p65795 s100
		+
		+	===== References =====</nodisp>

-	===== References =====

Managing mental symptoms

anonymous@undisclosed.example.com (Anonymous) — Wed, 14 Sep 2022 20:53:53 +0000

09.01.2019		current
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	A person with periodontal disease can clearly see her receded gums, and there is little ambiguity about the effect of constipation on a patient's gastrointestinal tract. On the other hand, those with illnesses with a profound mental component often have trouble recognizing that part of their condition for what it is. Instead, they tend to overestimate the role circumstance and personal choice play in how they feel.		A person with periodontal disease can clearly see her receded gums, and there is little ambiguity about the effect of constipation on a patient's gastrointestinal tract. On the other hand, those with illnesses with a profound mental component often have trouble recognizing that part of their condition for what it is. Instead, they tend to overestimate the role circumstance and personal choice play in how they feel.

-	By all indications, microbes exist in the brain as they do in any number of other unexpected locations: NASA clean rooms,(({{pubmed>long:17655710}})) two miles below the surface of a glacier(({{pubmed>long:16332755}})) and [[http://www.divediscover.whoi.edu/hottopics/bacteria.html\|hydrothermal vents]]. Further, an activated immune response is indiscriminate in what microbial communities it targets. Therefore, just as we would expect symptoms of any other conditions to be temporarily exacerbated by the MP, we also expect mental symptoms to become worse. Indeed, almost everyone who goes on the MP for a minimum length of time has some form of mental immunopathology.	+	By all indications, microbes exist in the brain as they do in any number of other unexpected locations: NASA clean rooms,(({{pmid>long:17655710}})) two miles below the surface of a glacier(({{pmid>long:16332755}})) and [[https://www.divediscover.whoi.edu/hottopics/bacteria.html\|hydrothermal vents]]. Further, an activated immune response is indiscriminate in what microbial communities it targets. Therefore, just as we would expect symptoms of any other conditions to be temporarily exacerbated by the MP, we also expect mental symptoms to become worse. Indeed, almost everyone who goes on the MP for a minimum length of time has some form of mental immunopathology.

	Further evidence can come from objectively assessing how symptoms wax and wane in accordance with the administration of antibiotics or olmesartan, or having another symptom. Some patients have commented that having one non-mental symptom such as arthritic pain can actually be a blessing as it offers to oneself (and one's doctor) an unequivocal signal that a person is suffering from immunopathology.		Further evidence can come from objectively assessing how symptoms wax and wane in accordance with the administration of antibiotics or olmesartan, or having another symptom. Some patients have commented that having one non-mental symptom such as arthritic pain can actually be a blessing as it offers to oneself (and one's doctor) an unequivocal signal that a person is suffering from immunopathology.
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	As with any immunopathology, consult the generic list of strategies for managing immunopathology including lowering antibiotics, adjusting olmesartan, or taking more frequent minocycline. Also consider:		As with any immunopathology, consult the generic list of strategies for managing immunopathology including lowering antibiotics, adjusting olmesartan, or taking more frequent minocycline. Also consider:

-	* [[home:lifestyle:light\|Restrict light]] – As discussed in the article [[home:othertreatments:sunshine\|Sunshine/light exposure as therapy]], in spite of a widespread belief that the peak occurs in late autumn and early winter,(({{pubmed>long:17688099}})) a positive correlation between sunlight and suicide has been demonstrated by several researchers. Exposure to light routinely causes mental immunopathology. For photosensitive patients intent on limiting symptoms due to light exposure, adequate eye protection is essential.	+	* [[home:lifestyle:light\|Restrict light]] – As discussed in the article [[home:othertreatments:sunshine\|Sunshine/light exposure as therapy]], in spite of a widespread belief that the peak occurs in late autumn and early winter,(({{pmid>long:17688099}})) a positive correlation between sunlight and suicide has been demonstrated by several researchers. Exposure to light routinely causes mental immunopathology. For photosensitive patients intent on limiting symptoms due to light exposure, adequate eye protection is essential.

	<blockquote>The short-term consequences of not wearing adequate eye protection will be an increase in neurological symptoms caused by stimulation of the Amygdala in the brain. These neurological symptoms include fatigue, irritability, aggressiveness, lack of concentration, brain fog, photosensitivity, transient loss of memory, mood swings, confusion, anxiety, anger, neurosis and even psychosis.		<blockquote>The short-term consequences of not wearing adequate eye protection will be an increase in neurological symptoms caused by stimulation of the Amygdala in the brain. These neurological symptoms include fatigue, irritability, aggressiveness, lack of concentration, brain fog, photosensitivity, transient loss of memory, mood swings, confusion, anxiety, anger, neurosis and even psychosis.
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	* [[home:social:talking\|Get support from family and friends]] – Struggling with chronic disease can strain the fabric of even the strongest families and relationships. Like those recovering from any other disease, patients battling chronic inflammatory disease want and need to have support from family members. Building that support has proven easier for some patients than others.		* [[home:social:talking\|Get support from family and friends]] – Struggling with chronic disease can strain the fabric of even the strongest families and relationships. Like those recovering from any other disease, patients battling chronic inflammatory disease want and need to have support from family members. Building that support has proven easier for some patients than others.
	* [[home:social:support\|Join (or start) a support group]] – The MP is a challenging multi-year therapy. As many MP veterans can attest, the chance to talk to a more experienced patient can significantly improve the odds of treatment success. While some patients may prefer to limit themselves to the online forums, an alternative possibility is that of a face-to-face support group. While there are currently only a few support groups, that can change over time. Patients who are interested in building a community of MP patients should seriously consider starting a support group.		* [[home:social:support\|Join (or start) a support group]] – The MP is a challenging multi-year therapy. As many MP veterans can attest, the chance to talk to a more experienced patient can significantly improve the odds of treatment success. While some patients may prefer to limit themselves to the online forums, an alternative possibility is that of a face-to-face support group. While there are currently only a few support groups, that can change over time. Patients who are interested in building a community of MP patients should seriously consider starting a support group.
		+	* A dog or cat may be a perfect companion.


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	{{tag>managing symptoms}}		{{tag>managing symptoms}}

		+	<nodisp>
	===== Notes and comments =====		===== Notes and comments =====

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	*Legacy content		*Legacy content
-	* http://www.marshallprotocol.com/view_topic.php?id=2696&forum_id=32&jump_to=134970#p134970	+	* https://www.marshallprotocol.com/view_topic.php?id=2696&forum_id=32&jump_to=134970#p134970
-	* http://www.marshallprotocol.com/forum32/12201.html	+	* https://www.marshallprotocol.com/forum32/12201.html
-	* http://www.marshallprotocol.com/view_topic.php?id=2218&forum_id=32&jump_to=80136#p80136	+	* https://www.marshallprotocol.com/view_topic.php?id=2218&forum_id=32&jump_to=80136#p80136


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-	=====References =====	+	=====References =====</nodisp>

Numbness (paresthesia and neuropathy)

anonymous@undisclosed.example.com (Anonymous) — Wed, 14 Sep 2022 20:53:53 +0000

01.12.2019		current
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-	<relatedarticle> [[home:diseases:pernicious_anemia\|Pernicious anemia]]</article>	+	<relatedarticle> [[home:diseases:peripheral_neuropathy\|Peripheral neuropathy]]</article>
	===== Types =====		===== Types =====

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-	Abnormal sensations such as prickling, tingling, itching, burning or cold, skin crawling or impaired sensations--are all called [[http://www.wrongdiagnosis.com/sym/paresthesias.htm\|parasthesia]]. These symptoms usually arise from nerve damage (neuropathy). Continued nerve damage can lead to numbness (lost of sensation) or paralysis (loss of movement and sensation).	+	Abnormal sensations such as prickling, tingling, itching, burning or cold, skin crawling or impaired sensations--are all called [[https://www.wrongdiagnosis.com/sym/paresthesias.htm\|parasthesia]]. These symptoms usually arise from nerve damage (neuropathy). Continued nerve damage can lead to numbness (lost of sensation) or paralysis (loss of movement and sensation).

	Paresthesia is one of the symptoms of Hypervitaminosis-D.		Paresthesia is one of the symptoms of Hypervitaminosis-D.
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	Neuropathy can result in muscle weakness if it causes reduced nervous stimulation to the muscles. This can occur in any muscle including chest muscles (making breathing difficult) or in the lower extremities (resulting in atrophy and difficulty walking).		Neuropathy can result in muscle weakness if it causes reduced nervous stimulation to the muscles. This can occur in any muscle including chest muscles (making breathing difficult) or in the lower extremities (resulting in atrophy and difficulty walking).

-	There are many causes of peripheral neuropathy (({{pubmed>long:28983799}})). It is a fairly common symptom of Th1 diseases (autoimmune diseases such as lupus and sarcoidosis) and indicates inflammation of the nervous system. Irritation to the nerve can also come from inflammation to the surrounding tissue (such as Rheumatoid Arthritis).	+	There are many causes of peripheral neuropathy (({{pmid>long:28983799}})). It is a fairly common symptom of Th1 diseases (autoimmune diseases such as lupus and sarcoidosis) and indicates inflammation of the nervous system. Irritation to the nerve can also come from inflammation to the surrounding tissue (such as Rheumatoid Arthritis).

	Impaired function and symptoms depend on the type of nerves -- motor, sensory, or autonomic -- that are damaged. Some people may experience temporary numbness, tingling, and pricking sensations, sensitivity to touch, or muscle weakness. Others may suffer more extreme symptoms, including burning pain (especially at night), muscle wasting, paralysis, or organ or gland dysfunction.		Impaired function and symptoms depend on the type of nerves -- motor, sensory, or autonomic -- that are damaged. Some people may experience temporary numbness, tingling, and pricking sensations, sensitivity to touch, or muscle weakness. Others may suffer more extreme symptoms, including burning pain (especially at night), muscle wasting, paralysis, or organ or gland dysfunction.
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		+	<nodisp>
	===== Notes and comments =====		===== Notes and comments =====

	removed Link		removed Link
-	There are many [[http://www.wrongdiagnosis.com/p/peripheral_neuropathy/underly.htm\|causes of peripheral neuropathy]].	+	There are many [[https://www.wrongdiagnosis.com/p/peripheral_neuropathy/underly.htm\|causes of peripheral neuropathy]].

	===== References =====		===== References =====
		+	</nodisp>

Insomnia and poor sleep

anonymous@undisclosed.example.com (Anonymous) — Wed, 14 Sep 2022 20:53:53 +0000

02.07.2019		current
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	* Practice relaxation techniques – do relaxation techniques for 30 to 60 minutes, which can be beneficial even if you do not sleep.		* Practice relaxation techniques – do relaxation techniques for 30 to 60 minutes, which can be beneficial even if you do not sleep.
	* Make the bedroom pitch black – do not use nightlights and ensure bedroom windows are completely light proof.		* Make the bedroom pitch black – do not use nightlights and ensure bedroom windows are completely light proof.
-	* Remove the TV from the bedroom and avoid light after a certain time – According to a recent study, exposure to electrical light between dusk and bedtime strongly suppresses melatonin levels and may impact physiologic processes regulated by melatonin signaling, such as sleepiness, thermoregulation, blood pressure and glucose homeostasis.(({{pubmed>long:21193540}}))	+	* Remove the TV from the bedroom and avoid light after a certain time – According to a recent study, exposure to electrical light between dusk and bedtime strongly suppresses melatonin levels and may impact physiologic processes regulated by melatonin signaling, such as sleepiness, thermoregulation, blood pressure and glucose homeostasis.(({{pmid>long:21193540}}))

	===== Sleep medications =====		===== Sleep medications =====
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	sarcoidosis, psoriasis, insomnia, kidney stones		sarcoidosis, psoriasis, insomnia, kidney stones

-	Read the [[http://bacteriality.com/2007/08/10/interview1/\|interview]]	+	Read the [[https://bacteriality.com/2007/08/10/interview1/\|interview]]

	<html></div></div>		<html></div></div>
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	chronic fatigue syndrome (CFS), depression, food sensitivities, insomnia		chronic fatigue syndrome (CFS), depression, food sensitivities, insomnia

-	Read the [[http://bacteriality.com/2007/11/10/interview10/\|interview]]	+	Read the [[https://bacteriality.com/2007/11/10/interview10/\|interview]]

	<html></div></div>		<html></div></div>
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-	<blockquote>I use a CD by Stephen Halpern called [[http://www.amazon.com/Sleep-Soundly/dp/B000S52UYQ\|Sleep Soundly]]. I have played this CD as I go to sleep for several years now and it has really helped my insomina.	+	<blockquote>I use a CD by Stephen Halpern called [[https://www.amazon.com/Sleep-Soundly/dp/B000S52UYQ\|Sleep Soundly]]. I have played this CD as I go to sleep for several years now and it has really helped my insomina.

	//Joy, MarshallProtocol.com// </blockquote>		//Joy, MarshallProtocol.com// </blockquote>
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	{{tag>managing symptoms neurological}}		{{tag>managing symptoms neurological}}

		+	<nodisp>
	===== Notes and comments =====		===== Notes and comments =====

		+	broken link [[https://www.physorg.com/print214129396.html\|described here]]

	* Legacy content		* Legacy content
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-	<blockquote>http://stereopsis.com/flux/research.html	+	<blockquote>https://stereopsis.com/flux/research.html

	started using the f.lux program after Claire posted about it last Fall. I just use a more low and less low setting for the "day" and "night" time frames. I do think it's possible it helps me feel sleepy around 9pm... but I rarely give in and go to bed at that point.		started using the f.lux program after Claire posted about it last Fall. I just use a more low and less low setting for the "day" and "night" time frames. I do think it's possible it helps me feel sleepy around 9pm... but I rarely give in and go to bed at that point.
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	Check article to see if it needs an added reminder about driver safety.		Check article to see if it needs an added reminder about driver safety.
	"Driver sleepiness is associated with 20 percent of serious car accidents."		"Driver sleepiness is associated with 20 percent of serious car accidents."
-	http://www.journalsleep.org/viewabstract.aspx?pid=27780	+	https://www.journalsleep.org/viewabstract.aspx?pid=27780
		+
		+	===== References =====</nodisp>

-	===== References =====