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home:diseases:anorexia_bulimia [08.12.2019] – [Further Research] sallieqhome:diseases:anorexia_bulimia [09.14.2022] (current) – external edit 127.0.0.1
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 Discussion in The Economist print edition 29 Sep 2005 Discussion in The Economist print edition 29 Sep 2005
-[[http://www.economist.com/displaystory.cfm?story_id=4455455|Molecular self-loathing]]+[[https://www.economist.com/displaystory.cfm?story_id=4455455|Molecular self-loathing]]
  
 ===== Evidence of infectious cause ===== ===== Evidence of infectious cause =====
  
- The intrinsic ability of bacteria to regulate their growth and to maintain their population within the gut suggests that gut bacteria can interfere with molecular pathways controlling energy balance in the host. (({{pubmed>long:27616451}}))+ The intrinsic ability of bacteria to regulate their growth and to maintain their population within the gut suggests that gut bacteria can interfere with molecular pathways controlling energy balance in the host. (({{pmid>long:27616451}}))
  
 ===== Immune overload ===== ===== Immune overload =====
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 An immune overload hypothesis would suggest that compensating withdrawal from some activities would help recovery from eating disorders, and certainly a reduction of unnecessary parental pressure may be needed. An immune overload hypothesis would suggest that compensating withdrawal from some activities would help recovery from eating disorders, and certainly a reduction of unnecessary parental pressure may be needed.
  
-[[http://www.eurekalert.org/pub_releases/2009-07/uoc--rpn072109.php|New imaging technology]] at U.Cal. San Diego provides insight into abnormalities in the brain circuitry of patients with anorexia nervosa that may contribute to the puzzling symptoms found in people with the eating disorder.+[[https://www.eurekalert.org/pub_releases/2009-07/uoc--rpn072109.php|New imaging technology]] at U.Cal. San Diego provides insight into abnormalities in the brain circuitry of patients with anorexia nervosa that may contribute to the puzzling symptoms found in people with the eating disorder.
 <blockquote>Under Kaye's leadership, the eating disorders treatment program at UC San Diego is developing treatments based on understanding the temperament and personality that drives anorexia, and helping patients to use such traits in constructive, rather then self-defeating ways.</blockquote>  <blockquote>Under Kaye's leadership, the eating disorders treatment program at UC San Diego is developing treatments based on understanding the temperament and personality that drives anorexia, and helping patients to use such traits in constructive, rather then self-defeating ways.</blockquote> 
  
  
 +
 +
 +
 +===== Patient experiences =====
 +
 +//Elijuh// Thu Dec 6th, 2007  light sensitivity 7 Anorexia 3 
 +
 +Sat Dec 15th, 2007 Anorexia 4 lost 3 pounds in 20 days 
 +
 +Dec 27th, 2007 
 +Anorexia is improving!  It's kinda funny that I had it during Christmas…must have been all the relatives!   
 +Mon Jan 14th, 2008  Notice I switched from the Ultracet to Demerol.  The Ultracet caused the anorexia to worsen tremendously.  I am six pounds down but staying steady there. ed May 6th, 2009 20:43 I am experiencing anorexia.  I don't even think about food.  No appetite.  I have begun setting a timer to remind me but I don't ever finish a meal.  Weight is down considerably.  Below 110. I am 5'5“.  This seems to be worse since I went for an esophagus dilation a few weeks ago.
 +
 +May 7th, 2009  I was tentatively diagnosed with Anorexia Nervosa in 1981.  Interestingly enough it seems to run in my family.  My grandmother died of AN in February of 2006.  5'7” and 83 lbs.  But when I was diagnosed with AN in 81, I obsessed about food.  I didn't eat it but it consumed my thoughts.  It was very inline with my OCD issues. I had rituals that surrounded my eating. With this IP, food isn't crossing my mind.  I think I'll try upping the Benicar first to see if my appetite returns. 
 +
 +Tue Jun 9th, 2009  My Anorexia is still here and now the Anorexia Nervosa stuff with the OCD issues is rearing it's ugly head, too. upping Benicar as of right now. It hit me tonight what was going on when a friend told me that I needed to eat and I argued them down.  Sigh.  Just like the old days.  Argue and then distract them.  It took me several days to realize I was back with the OCD stuff. 
 +
 +Support team: //You can back down the Zith, since you feel that it is causing all this, no need to hurry and xtra Benicar  OR  keep Zith where it is and add in Benicar 40mg/4hrs and use 20mg sublinigal (taste ugh!).//
 +
 +Tue Jun 7th, 2011 After 7 years of serious illness I am seeing huge improvements. ... Tumors in my feet - shrinking and pain is gone. Breathing - easier and better. Swollen rib cage - gone. Headaches - gone. Tendons - FINALLY some better - not great - but better. 
 +
 +Vomiting - almost gone- Now down to vomiting once or twice a week. Anemia - gone. White count back in normal range. Reflux - better. 
 +
 +I was having to sleep really elevated to keep the stomach acid from going into my lungs. I can sleep with the bed elevation lower now. Sleep is improved. No longer on any sleep meds…except when I'm worried. .... I'm not completely well but I am getting there. I know I have more years in recovery but I can do it
 +
 +So that is it. I am starting to feel normal again. I even have less of the nerve issues in my hands now. I didn't think things like that would ever go back to normal. But I can feel them normalizing. The word for me is beginning to be…NORMAL.  4.5 years on the Marshall, (was on one antibiotic protocol or another since July of 2005). 
  
  
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 Tortilla chips with salsas and guacamole. Tortilla chips with salsas and guacamole.
  
 +===== Further Research  =====
  
 +We found significantly altered correlations between alpha-MSH autoAb levels and the total Eating Disorder Inventory-2 score, as well as most of its subscale dimensions in AN and BN patients vs. controls. Remarkably, these correlations were opposite in AN vs. BN patients. In contrast, levels of autoAbs reacting with adrenocorticotropic hormone, OT, or VP had only few altered correlations with the Eating Disorder Inventory-2 subscale dimensions in AN and BN patients. Thus, our data reveal that core psychobehavioral abnormalities characteristic for eating disorders correlate with the levels of autoAbs against alpha-MSH, suggesting that AN and BN may be associated with autoAb-mediated dysfunctions of primarily the melanocortin system.  //Fetissov SO, et al//(({{pmid>long:16195379}}))
  
 +Hypovolemia-induced obesity and diabetes. (({{pmid>long:19709692}})) Hypovolemia is a diminished volume of circulating blood in the body. Therefore is it obviously important to guard against dehydration.
  
 +Imaging studies reveal[[https://www.eurekalert.org/pub_releases/2009-07/uoc--rpn072109.php|Differences]] in the brain circuitry of patients with anorexia nervosa (commonly known as anorexia) that may contribute to the puzzling symptoms found in people with the eating disorder.  (({{pmid>long:21243469}}))
  
  
 +[[https://www.plosone.org/article/info:doi/10.1371/journal.pone.0007125|Monitoring Bacterial Community]] of Human Gut Microbiota Reveals an Increase in Lactobacillus in Obese Patients and Methanogens in Anorexic Patients (({{pmid>long:19774074}})) 
  
-===== Patient experiences =====+Famine may affect the microbiome in a lasting way(({{pmid>long:14696131}})) 
 +[[https://www.ncbi.nlm.nih.gov/pubmed/14696131|psychological traits in eating disorders]]
  
-//Elijuh// Thu Dec 6th, 2007  light sensitivity 7 Anorexia 3  +in New Insights in Anorexia Nervosa (({{pmid>long:27445651}}))  
- +PGorwoodJEpelbaum and colleagues assemble seven possible modelseach accompanied by illustrative figures.
-Sat Dec 15th, 2007 Anorexia 4 lost 3 pounds in 20 days  +
- +
-Dec 27th, 2007  +
-Anorexia is improving!  It's kinda funny that I had it during Christmas…must have been all the relatives!    +
-Mon Jan 14th, 2008  Notice I switched from the Ultracet to Demerol.  The Ultracet caused the anorexia to worsen tremendously.  I am six pounds down but staying steady there. ed May 6th, 2009 20:43 I am experiencing anorexia.  I don't even think about food.  No appetite.  I have begun setting a timer to remind me but I don't ever finish a meal.  Weight is down considerably.  Below 110. I am 5'5“.  This seems to be worse since I went for an esophagus dilation a few weeks ago. +
- +
-May 7th, 2009  I was tentatively diagnosed with Anorexia Nervosa in 1981.  Interestingly enough it seems to run in my family.  My grandmother died of AN in February of 2006.  5'7” and 83 lbs.  But when I was diagnosed with AN in 81, I obsessed about food.  I didn't eat it but it consumed my thoughts.  It was very inline with my OCD issues. I had rituals that surrounded my eating. With this IP, food isn't crossing my mind.  I think I'll try upping the Benicar first to see if my appetite returns.  +
- +
-Tue Jun 9th, 2009  My Anorexia is still here and now the Anorexia Nervosa stuff with the OCD issues is rearing it's ugly head, too. upping Benicar as of right now. It hit me tonight what was going on when a friend told me that I needed to eat and I argued them down.  Sigh.  Just like the old days.  Argue and then distract them.  It took me several days to realize I was back with the OCD stuff.  +
- +
-Support team//You can back down the Zith, since you feel that it is causing all this, no need to hurry and xtra Benicar  OR  keep Zith where it is and add in Benicar 40mg/4hrs and use 20mg sublinigal (taste ugh!).// +
- +
-Tue Jun 7th2011 After 7 years of serious illness I am seeing huge improvements... Tumors in my feet - shrinking and pain is gone. Breathing - easier and better. Swollen rib cage - gone. Headaches - gone. Tendons - FINALLY some better - not great - but better.  +
- +
-Vomiting - almost gone- Now down to vomiting once or twice a week. Anemia - gone. White count back in normal range. Reflux - better.  +
- +
-I was having to sleep really elevated to keep the stomach acid from going into my lungs. I can sleep with the bed elevation lower now. Sleep is improved. No longer on any sleep meds…except when I'm worried. .... I'm not completely well but I am getting there. I know I have more years in recovery but I can do it +
- +
-So that is it. I am starting to feel normal again. I even have less of the nerve issues in my hands now. I didn't think things like that would ever go back to normal. But I can feel them normalizing. The word for me is beginning to be…NORMAL.  4.5 years on the Marshall(was on one antibiotic protocol or another since July of 2005)+
  
  
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 +<nodisp>
 ===== Notes and comments ===== ===== Notes and comments =====
  
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   * legacy content   * legacy content
-  * [[http://www.marshallprotocol.com/view_topic.php?id=4243&forum_id=37&jump_to=39895#p39895]] s60+  * [[https://www.marshallprotocol.com/view_topic.php?id=4243&forum_id=37&jump_to=39895#p39895]] s60
    
  
  
 (//Paul and/or Amy// ??) I'm not sure I can completely tease out the significance of this study, but this sort of result suggests that famine may affect the microbiome in a lasting way: (//Paul and/or Amy// ??) I'm not sure I can completely tease out the significance of this study, but this sort of result suggests that famine may affect the microbiome in a lasting way:
-[[http://www.ncbi.nlm.nih.gov/pubmed/14696131|psychological traits in eating disorders]]+[[https://www.ncbi.nlm.nih.gov/pubmed/14696131|psychological traits in eating disorders]]
  
 Final point: IMO, we should all be careful not to define the chain of events. What if a disruption in the microbiome preceded anorexia and the anorexia "phenotype" was only expressed in certain cultures? Final point: IMO, we should all be careful not to define the chain of events. What if a disruption in the microbiome preceded anorexia and the anorexia "phenotype" was only expressed in certain cultures?
  
-===== References =====+===== References =====</nodisp> 
home/diseases/anorexia_bulimia.1565651307.txt.gz · Last modified: 08.12.2019 by sallieq
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