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home:diseases:anxiety [08.13.2019] – [Patient interviews] sallieqhome:diseases:anxiety [01.26.2020] – [Research into various drug effects] sallieq
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 //**Greg Blaney, MD**// </blockquote> //**Greg Blaney, MD**// </blockquote>
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 +===== Research into various drug effects =====
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 + findings suggest that a low dose of THC produces subjective stress-relieving effects in line with those commonly reported among cannabis users, but that higher doses may non-specifically increase negative mood.  [[https://www.sciencedirect.com/science/article/abs/pii/S037687161730220X?via%3Dihub|effects of delta-9-THC on responses to the Trier Social Stress Test (TSST)Link]]
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 +baseline symptoms of depression (but not anxiety or stress) appeared to be exacerbated across time/tracked sessions. [[http://example.com|https://www.sciencedirect.com/science/article/pii/S0165032718303100?via%3Dihub Link]]
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 +Perhaps most well-studied is the role the CeA plays in unconditioned and conditioned fear generation (Ciocchi et al., 2010, Li et al., 2013, Tye et al., 2011), fear extinction, and conditioned inhibition (Amano et al., 2010), as well as conditioned orienting responses to emotionally salient stimuli (El-Amamy and Holland, 2007, Groshek et al., 2005).  [[https://www.cell.com/neuron/fulltext/S0896-6273(14)00017-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627314000178%3Fshowall%3Dtrue|The central amygdala Link]]
  
 +the mechanisms by which stress increases amygdala-dmPFC synaptic strength and generates anxiety-like behaviors are not well understood. Here, we show that the mouse basolateral amygdala (BLA)-prelimbic prefrontal cortex (plPFC) circuit is engaged by stress and activation of this pathway in anxiogenic. [[https://www.cell.com/neuron/fulltext/S0896-6273(19)31090-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627319310906%3Fshowall%3Dtrue|Functional coupling between the amygdala and the dorsomedial prefrontal cortex Link]]
 ===== Notes and comments ===== ===== Notes and comments =====
  
home/diseases/anxiety.txt · Last modified: 09.14.2022 by 127.0.0.1
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