Home

Differences

This shows you the differences between two versions of the page.

Link to this comparison view

Both sides previous revision Previous revision
Next revision
Previous revision
home:diseases:cancer [07.11.2019]
sallieq [Recent research]
home:diseases:cancer [10.01.2019] (current)
sallieq [Screening and diagnosis]
Line 15: Line 15:
 =====Evidence of infectious cause===== =====Evidence of infectious cause=====
  
-According to D.L. Mager, “An overwhelming body of evidence has determined that relationships among certain bacteria and cancers exist.”(({{pubmed>​long:​14594792}})) ​ The growing number of examples of microbes associated with cancers include:+According to D.L. Mager, “An overwhelming body of evidence has determined that relationships among certain bacteria and cancers exist.”(({{pubmed>​long:​14594792}}))  ​ 
 + 
 +[[https://​bmccancer.biomedcentral.com/​track/​pdf/​10.1186/​s12885-017-3234-4|Infections and cancer: the “fifty shades of immunity” hypothesis]] ​  
 + 
 +The growing number of examples of microbes associated with cancers include:
  
   * **breast cancer** – Underscoring how cancer is a systemic disease, a 2006 study found that the gut bacteria //​Helicobacter hepaticus// induces mammary adenocarcinoma in mice.(({{pubmed>​long:​16885333}}))   * **breast cancer** – Underscoring how cancer is a systemic disease, a 2006 study found that the gut bacteria //​Helicobacter hepaticus// induces mammary adenocarcinoma in mice.(({{pubmed>​long:​16885333}}))
Line 303: Line 307:
  
 Cancer kills when it is "​invasive,"​ spreading from primary sites to other sites and proliferating there. The only sure way to know the disease is cancer is to allow it to progress to a point where there is no question one has a proliferative disease. Clearly, this is not a tenable option as at a certain point, it is impossible to intervene. However, the risk of a false positive is also great. Chemotherapy will destroy the immune system, allowing microbes to multiply and leading to greater chronic inflammation when chemotherapy is discontinued. These two considerations have to be balanced, and it is a matter of debate whether many oncologists fully appreciate this balance. It is worth noting that false positives increase the apparent "​success rate" of oncology, and there is therefore limited incentive to minimize them. Cancer kills when it is "​invasive,"​ spreading from primary sites to other sites and proliferating there. The only sure way to know the disease is cancer is to allow it to progress to a point where there is no question one has a proliferative disease. Clearly, this is not a tenable option as at a certain point, it is impossible to intervene. However, the risk of a false positive is also great. Chemotherapy will destroy the immune system, allowing microbes to multiply and leading to greater chronic inflammation when chemotherapy is discontinued. These two considerations have to be balanced, and it is a matter of debate whether many oncologists fully appreciate this balance. It is worth noting that false positives increase the apparent "​success rate" of oncology, and there is therefore limited incentive to minimize them.
 +
 +Papillary carcinomas are a special histological type of breast cancer, and have a relatively good outcome. (({{pubmed>​long:​22025283}}))
  
 ====Screenings not as effective as touted ==== ====Screenings not as effective as touted ====
Line 388: Line 394:
  
 ===== Recent research ===== ===== Recent research =====
 +
 +Senescent cells contribute to both age-related degeneration and hyperplastic pathologies,​ including cancer. (({{pubmed>​long:​31138644}}))
 +
  
 Paclitaxel Reduces Tumor Growth by Reprogramming Tumor-Associated Macrophages to an M1 Profile in a TLR4-Dependent Manner. ​ (({{pubmed>​long:​30104241}})) ​ Paclitaxel Reduces Tumor Growth by Reprogramming Tumor-Associated Macrophages to an M1 Profile in a TLR4-Dependent Manner. ​ (({{pubmed>​long:​30104241}})) ​
Line 423: Line 432:
   * [[http://​www.youtube.com/​watch?​v=s-uCeh7BGBY|Inflammation,​ metabolism, aging and cancer: Dangerous Liaisons]] – Distinguished Prof. Michael Karin 2010 Harvey Prize Laureate delivered this lecture at the Technion Rappaport Faculty of Medicine on March 14, 2011. Prof. Karin received the Harvey prize in recognition of his pioneering research that has led to the deciphering of the molecular mechanisms by which mammalian cells respond to inflammatory cytokines, environmental stress and various pathogens. ​   * [[http://​www.youtube.com/​watch?​v=s-uCeh7BGBY|Inflammation,​ metabolism, aging and cancer: Dangerous Liaisons]] – Distinguished Prof. Michael Karin 2010 Harvey Prize Laureate delivered this lecture at the Technion Rappaport Faculty of Medicine on March 14, 2011. Prof. Karin received the Harvey prize in recognition of his pioneering research that has led to the deciphering of the molecular mechanisms by which mammalian cells respond to inflammatory cytokines, environmental stress and various pathogens. ​
   * [[http://​www.oatext.com/​pdf/​ICST-4-231.pdf|2017 review of RAS system observations suggesting cancer stem cells may be a novel therapeutic target]]   * [[http://​www.oatext.com/​pdf/​ICST-4-231.pdf|2017 review of RAS system observations suggesting cancer stem cells may be a novel therapeutic target]]
 +  * [[http://​cancerres.aacrjournals.org/​content/​79/​13_Supplement/​5282.short|2019 focusing on how senescence occurs in epithelial cells, the cells that line the surfaces of the organs and structures in the body and the type of cells in which most cancers arise]] ​
 +
   *  Bicarbonate of soda may even contribute to cancer prevention.(({{pubmed>​long:​28083722}}))   *  Bicarbonate of soda may even contribute to cancer prevention.(({{pubmed>​long:​28083722}}))
   * [[http://​www.reuters.com/​article/​2012/​01/​07/​us-argentina-fernandez-idUSTRE8060CB20120107|Argentina'​s Fernandez sent home, never had cancer]] – Argentine President Cristina Fernandez never had cancer despite being diagnosed with the disease last month and having her thyroid gland removed.   * [[http://​www.reuters.com/​article/​2012/​01/​07/​us-argentina-fernandez-idUSTRE8060CB20120107|Argentina'​s Fernandez sent home, never had cancer]] – Argentine President Cristina Fernandez never had cancer despite being diagnosed with the disease last month and having her thyroid gland removed.
home/diseases/cancer.1562884277.txt.gz · Last modified: 07.11.2019 by sallieq
© 2015, Autoimmunity Research Foundation. All Rights Reserved.