Home

Differences

This shows you the differences between two versions of the page.

Link to this comparison view

Both sides previous revisionPrevious revision
Next revision
Previous revision
Last revisionBoth sides next revision
home:diseases:hashimotos [01.01.2019] – [Hashimoto's disease] sallieqhome:diseases:hashimotos [01.18.2020] – [Other evidence] sallieq
Line 3: Line 3:
 ====== Hashimoto's disease ====== ====== Hashimoto's disease ======
  
-<relatedarticle> [[home:diseases:graves|Grave'disease]] </article>+<relatedarticle> [[home:diseases:graves|Graves' disease]] </article>
  
 ===== Introduction ===== ===== Introduction =====
Line 12: Line 12:
 <blockquote>Women with Hashimotos thyroiditis suffer from a high symptom load. Hypothyroidism is only a contributing factor to the development of associated conditions.(({{pubmed>long:21186954}}))</blockquote> <blockquote>Women with Hashimotos thyroiditis suffer from a high symptom load. Hypothyroidism is only a contributing factor to the development of associated conditions.(({{pubmed>long:21186954}}))</blockquote>
  
-An infectious etiology has long been suspected in different thyroid diseases, including Hashimoto's thyroiditis. As with many other inflammatory diseases most reasearchers appear to be searching for one specific culprit, something which seems ulikely in light of the many findings of links to many different viruses and bacteria in thyroid disease. Further, in the light of last few years' progress in metagenomics, a multimicrobial, successive type infection appears more likely to drive the disease process.(({{pubmed>long:23370376}}))  +An infectious etiology has long been suspected in different thyroid diseases, including Hashimoto's thyroiditis. As with many other inflammatory diseases most reasearchers appear to be searching for one specific culprit, something which seems unlikely in light of the many findings of links to many different viruses and bacteria in thyroid disease. Further, in the light of the last few years' progress in metagenomics, a multimicrobial, successive type infection appears more likely to drive the disease process.(({{pubmed>long:23370376}}))  
  
 ===== Evidence of infectious cause ===== ===== Evidence of infectious cause =====
Line 19: Line 19:
  
 Also, inflammatory thyroid disease has also been shown to occur as part of the immmunopathology resulting from treatment of HIV infection.(({{pubmed>long:22784301}})) In line with the Marshall Pathogenesis of inflammatory disease, this is most readily explained by an enhanced function of the immune system upon initiating antiviral therapy, revealing subclinical thyroid disease and multimicrobial infection of the thyroid gland.  Also, inflammatory thyroid disease has also been shown to occur as part of the immmunopathology resulting from treatment of HIV infection.(({{pubmed>long:22784301}})) In line with the Marshall Pathogenesis of inflammatory disease, this is most readily explained by an enhanced function of the immune system upon initiating antiviral therapy, revealing subclinical thyroid disease and multimicrobial infection of the thyroid gland. 
-==== Other evidence ====+==== Research ====
  
 Patients suffering from Hashimoto's disease have lower levels of vitamin 25-D, and disease severity correlates with vitamin D levels.(({{pubmed>long:23337162}})) In line with the Marshall Pathogenesis of inflammatory disease, this points to microbes having subverted the function of the vitamin D receptor.  Patients suffering from Hashimoto's disease have lower levels of vitamin 25-D, and disease severity correlates with vitamin D levels.(({{pubmed>long:23337162}})) In line with the Marshall Pathogenesis of inflammatory disease, this points to microbes having subverted the function of the vitamin D receptor. 
  
 The ratio of Th1/Th2 cells is higher in Hashimoto's, indicating presence of intracellular infection.(({{pubmed>long:19415997}})) The ratio of Th1/Th2 cells is higher in Hashimoto's, indicating presence of intracellular infection.(({{pubmed>long:19415997}}))
 +
 +Selenium and iodine are essential for thyroid hormone synthesis and function.(({{pubmed>long:26088475}})) 
 +
 +
  
  
home/diseases/hashimotos.txt · Last modified: 09.14.2022 by 127.0.0.1
© 2015, Autoimmunity Research Foundation. All Rights Reserved.