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home:diseases:osteoporosis_osteopenia [02.18.2019] – [Other treatments] sallieqhome:diseases:osteoporosis_osteopenia [07.04.2019] – [Cannabinoids] sallieq
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 ====== Osteoporosis and osteopenia ====== ====== Osteoporosis and osteopenia ======
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 +<relatedarticle> [[home:diseases:hyperparathyroidism|Secondary hyperparathyroidism]] </article>
  
 Both osteoporosis and osteopenia are diseases marked by a decrease in bone mineral density. Osteopenia is a less severe form of and sometimes precursor to osteoporosis. The loss of bone mass leads to a porous bone structure, frequent fractures, and delayed healing. Both osteoporosis and osteopenia are diseases marked by a decrease in bone mineral density. Osteopenia is a less severe form of and sometimes precursor to osteoporosis. The loss of bone mass leads to a porous bone structure, frequent fractures, and delayed healing.
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 </blockquote> </blockquote>
  
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 +==== Cannabinoids  ====
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 +An optimal correlation of cannabinoid dose, duration, moment of action, and affinity can lead to an increased bone regeneration capacity  (({{pubmed>long:30702341}}))
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 +Heavy cannabis use is associated with low bone mineral density, low BMI, high bone turnover, and an increased risk of fracture. (({{pubmed>long:27593602}}))  [[https://www.amjmed.com/article/S0002-9343(17)30392-3/fulltext|Response by H W Daniell, M.D.]]
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 +[[https://www.amjmed.com/article/S0002-9343(17)30391-1/fulltext| interpretation of those results; suggestion by S M Hanis, M. Sc. and K Mansori, Ph. D.]]
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 +[[https://www.amjmed.com/article/S0002-9343(17)30613-7/fulltext|Reply: Sophocleous et al]]
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 +Cannabinoids induce incomplete maturation of cultured human leukemia cells. (({{pubmed>long:3037549}}))
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 +The psychoactive component of marijuana, delta9-tetrahydrocannabinol (THC) suppresses different functions of immunocytes, including the antimicrobicidal activity of macrophages. (({{pubmed>long:10733093}}))
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 + the first observations of GcMAF effects on the transcriptionomics of the endocannabinoid system and expression of CB2R protein. These data point to a potential nexus between endocannabinoids, vitamin D and its transporter proteins, and the immune dysregulations observed with autism. (({{pubmed>long:    24739187}}))
  
 ==== Calcium supplementation ==== ==== Calcium supplementation ====
home/diseases/osteoporosis_osteopenia.txt · Last modified: 09.14.2022 by 127.0.0.1
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