Differences

This shows you the differences between two versions of the page.

--- home:othertreatments:antioxidants [07.03.2011] – [Interference with apoptosis] paulalbert
+++ home:othertreatments:antioxidants [07.03.2011] – [Interference with apoptosis] paulalbert
@@ Line 20: / Line 20: @@
 ==== Interference with apoptosis ====
-Apoptosis, or regulated cell suicide, eliminates unwanted and damaged cells, including precancerous and cancerous cells. Reactive oxygen species (ROS) are chemically-reactive molecules containing oxygen that act to neutralize antioxidants. In their 2000 study, Salganki //et al.// reasoned that since ROS act as essential apoptotic mediators, increasing the ROS level might enhance apoptosis and thereby slow down tumor growth.(({{pubmed>long:10783311}})) Provocatively, that team showed that tumor growth was inhibited in mice fed an antioxidant-depleted diet while an antioxidant-rich diet had no impact on tumor growth. This work, while preliminary, offers one mechanism how megadoses of antioxidants are not protective against cancer and may actually exacerbate it.
+Apoptosis, or regulated cell suicide, eliminates unwanted and damaged cells, including precancerous and cancerous cells. Reactive oxygen species (ROS) are chemically-reactive molecules containing oxygen, which act to neutralize antioxidants, regulate apoptosis(({{pubmed>long:11256882}})). In their 2000 study, Salganki //et al.// reasoned that since ROS act as essential apoptotic mediators, increasing the ROS level might enhance apoptosis and thereby slow down tumor growth.(({{pubmed>long:10783311}})) Provocatively, that team showed that tumor growth was inhibited in mice fed an antioxidant-depleted diet while an antioxidant-rich diet had no impact on tumor growth. This work, while preliminary, offers one mechanism how megadoses of antioxidants are not protective against cancer and may actually exacerbate unchecked cell growth.

home/othertreatments/antioxidants.txt · Last modified: 09.14.2022 by 127.0.0.1