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home:othertreatments:herbs_and_spices [12.15.2018] – [Curcumin, tumeric, curry and mustard] sallieqhome:othertreatments:herbs_and_spices [02.07.2019] – [Garlic] sallieq
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 ==== Curcumin, tumeric, curry and mustard ==== ==== Curcumin, tumeric, curry and mustard ====
  
-MP patients aree advised to avoid significant use of curcumin as well as its derivatives. A 2010 by Choi //et al.// showed that curcumin decreases androgen receptor expression in a dose-dependent manner.(({{pubmed>long:20680030}})) According to a 2006 Food Technology article: +MP patients are advised to avoid significant use of curcumin as well as its derivatives. A 2010 by Choi //et al.// showed that curcumin decreases androgen receptor expression in a dose-dependent manner.(({{pubmed>long:20680030}})) According to a 2006 Food Technology article: 
  
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 Garlic contains a chemical called allicin, which is a natural antibiotic.(({{pubmed>long:2469386}})) Allicin is known to inhibit bacterial cell growth. Garlic tablets taken as a supplement may interact unpredictably with MP medications and could be potentially detrimental. Eating moderate amounts of garlic as part of one's diet, however, is probably not detrimental to progress on the MP. Garlic contains a chemical called allicin, which is a natural antibiotic.(({{pubmed>long:2469386}})) Allicin is known to inhibit bacterial cell growth. Garlic tablets taken as a supplement may interact unpredictably with MP medications and could be potentially detrimental. Eating moderate amounts of garlic as part of one's diet, however, is probably not detrimental to progress on the MP.
  
 +[[https://aac.asm.org/content/56/5/2314|Ajoene, a Sulfur-Rich Molecule from Garlic, Inhibits Genes Controlled by Quorum Sensing]]
  
 +We identified four anti-inflammatory sulfur-containing compounds from garlic, and their chemical structures were identified as Z- and E-ajoene and oxidized sulfonyl derivatives of ajoene. The sulfur compounds inhibited the production of nitric oxide (NO) and prostaglandin E(2) (PGE(2)) and the expression of the pro-inflammatory cytokines tumor necrosis factor-α, interleukin-1β, and interleukin-6 in lipopolysaccharide (LPS)-activated macrophages. (({{pubmed>long:23057778}})) 
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 +The optimum conditions for the formation of E- and Z-ajoene from garlic juice (({{pubmed>long:25473520}})) 
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 +The treatment of macrophages with ajoene resulted in the activation of JNK, induction of ROS synthesis and accumulation of ROS, possibly leading to the activation of ER stress and autophagy. These results reveal the mechanism of the antimycobacterial effects of ajoene against Mtb H37Rv. Our findings might facilitate the development of novel therapies for patients with TB (({{pubmed>long:29239661}})) 
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 + In vitro, Ajoene is toxic for several tumoral cell lines, and exert an antiproliferative effect on T. cruzi and murine malaria parasites. Here we show that Ajoene strongly inhibited the proliferation induced in human lymphocytes by the mitogens phytohemagglutinin (PHA), phorbol myristate acetate (PMA) and anti-CD3, and the capping formation induced in B lymphocytes by anti-IgM antibodies. On macrophages, Ajoene was also found to partially inhibit the lypopolysaccharide-induced production of Tumor Necrosis Factor (TNF), and to decrease the phagocytic activity of thioglycolate-elicited mouse peritoneal macrophages for IgG-opsonized, human erythrocytes. Ajoene also partially prevented the lytic effect of human and rabbit TNF on Actinomycin D-treated WEHI 164 cells. These results strongly suggest that Ajoene is a potent modulator of membrane-dependent functions of immune cells. (({{pubmed>long:9049657}})) 
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 +Ajoene induces apoptosis in human promyeloleukemic cells, accompanied by generation of reactive oxygen species and activation of nuclear factor kappaB (({{pubmed>long:9495804}})) 
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 +In this study, we identified 18 essential oils (at 0.2% concentration) that are more active than 40 µM daptomycin (a persister drug control that could eradicate B. burgdorferi stationary phase cells), from which 10 essential oils stand out as having a remarkable activity even at 0.1% concentration (Table 1). Among them, garlic essential oil exhibited the best activity as shown by the lowest residual viability of B. burgdorferi at 0.1%. (({{pubmed>long:30332754}})) 
 ==== Grapefruit seed extract ==== ==== Grapefruit seed extract ====
  
home/othertreatments/herbs_and_spices.txt · Last modified: 09.14.2022 by 127.0.0.1
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