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home:pathogenesis:evidence_bacteria [01.13.2020] – [Other evidence] sallieqhome:pathogenesis:evidence_bacteria [01.13.2020] – [Other evidence] sallieq
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 ===== Other evidence ===== ===== Other evidence =====
  
-There is also the following types of evidence, the first three of which are noted in a [[http://www.medicinejournal.co.uk/article/S1357-3039(06)00185-X/abstract|1998 article]] and 2005 paper(({{pubmed>long:9779355}})) by David Relman and David Fredricks:+There is also the following types of evidence, the first three of which are noted in a [[http://www.medicinejournal.co.uk/article/S1357-3039(06)00185-X/abstract|1998 article]] and 2005(({{pubmed>long:9779355}})) paper by David Relman and David Fredricks:
   * **Clinical features** – Chronic diseases often share the same clinical presentation as those of known infectious diseases including fever and leucocytosis (an elevated number of white cells in the blood).   * **Clinical features** – Chronic diseases often share the same clinical presentation as those of known infectious diseases including fever and leucocytosis (an elevated number of white cells in the blood).
   * **Histology** – The inflammation of affected tissues in a chronic disease is very similar to inflammation caused by infection of characteristic microbial structures. [[http://en.wikipedia.org/wiki/Granuloma|Granuloma]] (an organized collection of immune cells) are widely agreed to be precipitated by infectious diseases such as tuberculosis, leprosy, histoplasmosis, cryptococcosis, blastomycosis, coccidioidomycosis and syphilis.(({{pubmed>long:14527294}})) However, a number of researchers continue to assume that certain chronic diseases such as sarcoidosis and Crohn's disease are not caused by infection even though they present with granuloma which are similar to those found in diseases known to be infectious. In fact, a Japanese team showed that one could use //Propionibacterium acnes// in mice to induce lung granuloma mimicking sarcoidosis.(({{pubmed>long:20424662}}))   * **Histology** – The inflammation of affected tissues in a chronic disease is very similar to inflammation caused by infection of characteristic microbial structures. [[http://en.wikipedia.org/wiki/Granuloma|Granuloma]] (an organized collection of immune cells) are widely agreed to be precipitated by infectious diseases such as tuberculosis, leprosy, histoplasmosis, cryptococcosis, blastomycosis, coccidioidomycosis and syphilis.(({{pubmed>long:14527294}})) However, a number of researchers continue to assume that certain chronic diseases such as sarcoidosis and Crohn's disease are not caused by infection even though they present with granuloma which are similar to those found in diseases known to be infectious. In fact, a Japanese team showed that one could use //Propionibacterium acnes// in mice to induce lung granuloma mimicking sarcoidosis.(({{pubmed>long:20424662}}))
home/pathogenesis/evidence_bacteria.txt · Last modified: 09.14.2022 by 127.0.0.1
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