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home:pathogenesis:familial_aggregation [05.02.2011] – external edit 127.0.0.1home:pathogenesis:familial_aggregation [09.21.2011] – paulalbert
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   * **sarcoidosis** – A six-year study of the Th1 disease sarcoidosis, conducted by the National Heart, Lung and Blood Institute at the National Institutes of Health (NIH) in Maryland found that among the 215 study participants who had been diagnosed with sarcoidosis, there were five husband-and-wife couples that both had the disease.  Yet sarcoidosis is such a rare disease that, statistically speaking, there should have been none.  This means the incidence of sarcoidosis in spouses in the study was 1,000 greater than could be expected by chance. The researchers also noted that the risk for sarcoidosis increased nearly five-fold in parents and siblings of people with the disease. (({{pubmed>long:17684288}}))   * **sarcoidosis** – A six-year study of the Th1 disease sarcoidosis, conducted by the National Heart, Lung and Blood Institute at the National Institutes of Health (NIH) in Maryland found that among the 215 study participants who had been diagnosed with sarcoidosis, there were five husband-and-wife couples that both had the disease.  Yet sarcoidosis is such a rare disease that, statistically speaking, there should have been none.  This means the incidence of sarcoidosis in spouses in the study was 1,000 greater than could be expected by chance. The researchers also noted that the risk for sarcoidosis increased nearly five-fold in parents and siblings of people with the disease. (({{pubmed>long:17684288}}))
   * **hypertension** – Researchers at Queens Medical School in England found that men whose spouses had hypertension had a two-fold increased risk of hypertension. Similarly, women whose spouses had hypertension also doubled their risk of developing the disease. The risk for both male and female subjects persisted after adjustment for other variables such as diet. (({{pubmed>long:9830183}}))   * **hypertension** – Researchers at Queens Medical School in England found that men whose spouses had hypertension had a two-fold increased risk of hypertension. Similarly, women whose spouses had hypertension also doubled their risk of developing the disease. The risk for both male and female subjects persisted after adjustment for other variables such as diet. (({{pubmed>long:9830183}}))
 +  * **exfoliative glaucoma** – In the middle Norway eye-screening study, the prevalence of XFG in both members of married couples is significantly higher than expected, "thereby suggesting a common environmental (probably infectious) agent, which may be of aetiological significance for the XFG development."(({{pubmed>long:19854735}}))
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 ==== Family members develop the same diseases ==== ==== Family members develop the same diseases ====
home/pathogenesis/familial_aggregation.txt · Last modified: 09.14.2022 by 127.0.0.1
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