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home:physicians:vitamin_d_leaflet [06.26.2018] – [The body controls activity of the VDR through regulation of the Vitamin D Metabolites] sallieq | home:physicians:vitamin_d_leaflet [10.13.2018] – [The body controls activity of the VDR through regulation of the Vitamin D Metabolites] sallieq | ||
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Only in homo sapiens is the VDR responsible for expression of the Cathelicidin antimicrobial peptide, the primary defense of the intra-phagocytic innate immune system. | Only in homo sapiens is the VDR responsible for expression of the Cathelicidin antimicrobial peptide, the primary defense of the intra-phagocytic innate immune system. | ||
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+ | ==== Notes and comments ==== | ||
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+ | ==== Headline ==== | ||
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==== Humans Are Not Tall Mice Without Tails! ==== | ==== Humans Are Not Tall Mice Without Tails! ==== | ||
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Importantly, | Importantly, | ||
- | You cannot study the vitamin D receptor in mice, how it relates to the immune system, and expect it to translate to Homo sapiens. Whereas in man the VDR transcribes cathelicidin, | + | You cannot study the vitamin D receptor in mice, how it relates to the immune system, and expect it to translate to Homo sapiens. Whereas in man the VDR transcribes cathelicidin, |
In mice, there are other receptors, and other genes that do that. Even the higher primates do not emulate the cathelicidin innate immunity of Homo sapiens. | In mice, there are other receptors, and other genes that do that. Even the higher primates do not emulate the cathelicidin innate immunity of Homo sapiens. |