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home:physicians [12.18.2018]
sallieq [Resources for physicians]
home:physicians [12.18.2018] (current)
sallieq [Resources for physicians]
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 diagnosis is not as important as the clinical assessment by an interested health care provider, the results of a [[home:​starting:​therapeutic_probe|therapeutic probe]], and outcome of the [[home:​tests:​vitdinterpretation|vitamin D metabolites blood test]].(({{pubmed>​long:​19758177}})) ​ diagnosis is not as important as the clinical assessment by an interested health care provider, the results of a [[home:​starting:​therapeutic_probe|therapeutic probe]], and outcome of the [[home:​tests:​vitdinterpretation|vitamin D metabolites blood test]].(({{pubmed>​long:​19758177}})) ​
  
-According to the Marshall Pathogenesis,​ chronic inflammatory disease is characterized by dysregulation of the nuclear receptor pathways which control the innate immune response. For example, the Vitamin D nuclear receptor (VDR) expresses many of the body's antimicrobial peptides (along with TLR2). In addition to down-regulation of expression of the VDR itself by many common bacteria and viruses, antagonistic microbial metabolites incrementally block ligands from activating it. Ingested vitamin D slows activity of the receptor in this same manner, preventing the body from killing the pathogens at the heart of the disease state. ​ That is why avoidance of ingested vitamin D (in food and supplements) is essential for the innate immune system to recover ​while patients are on the MP.(({{pubmed>​long:​19393200}})) ((Waterhouse JC, Marshall TG, Fenter B, Mangin M, Blaney G. [[home:​publications:​waterhouse_new_research_2006|High levels of active 1,​25-dihydroxyvitamin D despite low levels of the 25-hydroxyvitamin D precursor — Implications of dysregulated vitamin D for diagnosis and treatment of Chronic Disease]]. In //Vitamin D: New Research//​. ​+According to the Marshall Pathogenesis,​ chronic inflammatory disease is characterized by dysregulation of the nuclear receptor pathways which control the innate immune response. For example, the Vitamin D nuclear receptor (VDR) expresses many of the body's antimicrobial peptides (along with TLR2). In addition to down-regulation of expression of the VDR itself by many common bacteria and viruses, antagonistic microbial metabolites incrementally block ligands from activating it. Ingested vitamin D slows activity of the receptor in this same manner, preventing the body from killing the pathogens at the heart of the disease state. ​ That is why avoidance of ingested vitamin D (in food and supplements) is essential for the innate immune system to recover. (({{pubmed>​long:​19393200}})) ((Waterhouse JC, Marshall TG, Fenter B, Mangin M, Blaney G. [[home:​publications:​waterhouse_new_research_2006|High levels of active 1,​25-dihydroxyvitamin D despite low levels of the 25-hydroxyvitamin D precursor — Implications of dysregulated vitamin D for diagnosis and treatment of Chronic Disease]]. In //Vitamin D: New Research//​. ​
 Volume 1. Edited by: Stoltz VD. New York: Nova Science Publishers; 2006. ISBN: 1-60021-000-7.))  ​ Volume 1. Edited by: Stoltz VD. New York: Nova Science Publishers; 2006. ISBN: 1-60021-000-7.))  ​
  
home/physicians.txt · Last modified: 12.18.2018 by sallieq
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