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Epilepsy (seizures)

Seizures are Th1-related. For example, one member had a grand-mal seizure after mistakenly taking a full tablet of Azithromycin at the start of Phase 2.

Evidence of infectious cause

  • An association between epileptic seizures and increased serum bacterial antibody levels - 1
  • Innate immune reaction in response to seizures2
  • Virological and immunological aspects of seizure disorders 3
  • Viruses and the immune system 4
  • Role of viral infections in the etiology of febrile seizures. 5

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In the majority of seizure disorders, no cause is ever found. It wouldn't be surprising if one of the causes of the disturbance in the brain's electrical activity that causes a seizure is Th1 inflammationThe complex biological response of vascular tissues to harmful stimuli such as pathogens or damaged cells. It is a protective attempt by the organism to remove the injurious stimuli as well as initiate the healing process for the tissue..

Treatment depends on whether the underlying cause can be determined and how many seizures the person has had. It is fine to continue taking the seizure medications ordered by your doctor. As you progress on the MP, you can discuss the possibility of weaning from the anti-seizure drugs.

Valium is sometimes used to prevent seizures. In our experience, it is important to use brand name Valium rather than a generic. See When and why should I use Valium?

Keep in mind that seizure activity could be caused by an immune system reaction at any time while on the MP. To be sure that you are safe, take the usual seizure precautions and work with the study site moderators and your doctor to achieve tolerable immunopathologyA state in which a patient has maintained an acceptable intensity of bacterial die-off reaction. The primary goal of the Marshall Protocol. by the adjustment of meds dosing and schedule while diligently avoiding sun/lights and Vitamin D.

Seizure disorders are common in Th1 diseases

In my opinion, seizure disorders are very common in Th1 diseases including borrelia. However, frank grand mal seizures are the least common. Variants of petit mal, 'spacing out', loss of train of thought, muscle twitches, restless leg syndrome etc are all seizure disorders.

The 'blacking out' that I have described and which are not uncommon as Herx reactions, are seizures, IMO. Also, emotional outbursts, again common in Th1 diseases, may be temporal lobe seizures. ~Greg Blaney, MD

Monitor serum depokote closely

Meds, such as depakote, whose doses are determined by blood levels need more frequent serum measurements to monitor possible changing needs as inflammationThe complex biological response of vascular tissues to harmful stimuli such as pathogens or damaged cells. It is a protective attempt by the organism to remove the injurious stimuli as well as initiate the healing process for the tissue. resolves and biochemistry changes.

Members experiences with seizures while on the MP

At least one member of the MP cohort has epilepsy, and the epileptic activity seems to modulated by immunopathologyA temporary increase in disease symptoms experienced by Marshall Protocol patients that results from the release of cytokines and endotoxins as disease-causing bacteria are killed.. Epilepsy is probably a Th1 disease.

..Trevor..

I have myoclonic seizures, fewer now since I have been on antibiotics, actually TREATING the disease, instead of pallative measures. I believe they are due to the disease, as the onset of seizure activity coincided with the onset of my illness.

We know bacteria reside in the CNS, and that neurotransmitters, hormones, regulatory functions are all disrupted by these infections. I am fortunate, in that they are not sudden onset, I feel them coming on, and can take medication. As the critters croak—the manifestations of the disease will lessen. ~hrts4me

I had a seizure 6 weeks ago, first ever in my life. I got up early, started down the stairs and fell. I was unconscious when my husband went to pick me up but then had the seizure. I saw a neurologist today who is pretty sure it's from neuro-sarc.

I guess I'm just surprised that I had a seizure after being on the MP for this long, my life is so much better for being on the MP I wouldn't have imagined anything going awry. ~Sue K

Read more:

Notes and comments

===== Symptoms ===== ===== Management ===== ===== Other treatments ===== ===== Tests ===== ===== Diagnosis ===== ===== Epidemiology ===== ===== Types ===== ===== Evidence of infectious cause===== ===== Role of vitamin D metabolism ===== ===== Politics ===== ===== Patient interviews ===== ===== Presentations and publications=====

REVISE

References

1) Iivanainen M, Hietala J, Malkamäki M, Waltimo O, Valtonen VV An association between epileptic seizures and increased serum bacterial antibody levels. Epilepsia. 1983;24:584-7.
3) Eeg-Olofsson O Virological and immunological aspects of seizure disorders. Brain Dev. 2003;25:9-13.
4) Getts DR, Balcar VJ, Matsumoto I, Müller M, King NJ Viruses and the immune system: their roles in seizure cascade development. J Neurochem. 2008;104:1167-76.
5) Millichap JG, Millichap JJ Role of viral infections in the etiology of febrile seizures. Pediatr Neurol. 2006;35:165-72.
Last modified: 05.31.2010
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