
According to the Marshall Pathogenesis, light-related changes in mood can be attributed to fluctuations in 1,25-dihydroxyvitamin D (1,25-D). Such reactions exist in people who suffer from “seasonal affective disorder” as well as those who are addicted to or dependent upon tanning.
Contrary to popular belief, epidemiological research points to an increase in suicide across countries during the beginning of the summer months when people tend to get more light exposure.
Light exposure does nothing to resolve underlying disease state and can actually delay progress for Marshall Protocol (MP) patients. Certainly prolonged light exposure has been shown to increase skin melanoma – the World Health Organization now categorizes tanning beds under the highest cancer risk category.1
MP patients who have completed the treatment have been able to attest to the fact that sunshine is not necessary for good health or happiness.
Despite what some researchers have argued, latitude studies that try to tie ambient solar UV radiation to prevalence of disease have been inconclusive.
In spite of a widespread belief that the peak occurs in late autumn and early winter,2 a positive correlation between sunlight and suicide has been demonstrated by several researchers.
We found a remarkably consistent pattern of seasonality with peak incidence around June in the northern hemisphere and December in the southern hemisphere. Moreover, there was a positive association between the seasonal amplitude of suicide (measured by relative risk) and total sunshine in the corresponding country. These findings indicate that sunshine may have a triggering effect on suicide….
Eleni Petridou, et al 3
Petridou's work is striking, because it identifies an effect for all 20 countries studied:
Increased summer incidence of suicide has also been identified in other countries including Finland,4 Norway,5 Belgium,6 France,7 Italy,8 Japan,9 USA,10 Lithuania,11 Switzerland,12 Chile,13 and South Africa.14
In many, if not all, of these studies the increased incidence of suicide was shown to be independent of an increase in homicide.
The Vitamin D Receptor (VDR) is at the heart of innate immunityThe body's first line of defense against intracellular and other pathogens. According to the Marshall Pathogenesis the innate immune system becomes disabled as patients develop chronic disease., transcribing over 913 genes. In a healthy person, conversion of additional 25-D into 1,25-D leads to the transcription of antimicrobial peptides and bacterial die-off. In a patient sick with chronic disease the VDR is blocked by bacterial ligands and levels of 1,25-D escalate to the point where other receptors are blocked from transcribing their antimicrobial peptides. An inactive immune response leads to a reduction in immunopathologyA temporary increase in disease symptoms experienced by Marshall Protocol patients that results from the release of cytokines and endotoxins as disease-causing bacteria are killed. and consequently feelings of temporary well-being.
This phenomenon can be observed among different patient populations.
In recent years, researchers have begun to describe people addicted to tanning, at least according to criteria set out by the Diagnostic and Statistical Manual for substance-related disorders.15 One research team calls the addiction “UV light substance-related disorder.”16
Whether it is an addiction or dependency, the Marshall Pathogenesis states that people who experience symptom relief following light exposure are being immunosuppressed.
Conversely, when a patient's 1,25-D is reduced, activity of the innate immune system increases as do symptoms of disease. This can be seen in people said to suffer from seasonal affective disorder (SAD), a mood disorder in which people who have normal mental health throughout most of the year experience depressive symptoms in the winter.
My mood improved seriously when I started wearing NoIRsSpecial sunglasses worn by Marshall Protocol patients to block light., the most powerful antidepressivum I ever used. Did not start the benicar yet. The antidepressive effect of avoiding bright light is an impressive proof for 1,25D being involved in depression.
Nightshade, MarshallProtocol.com
The “sparkle” is back. Now I don't feel depressed at all like I have in years past. No more SAD.
DThomas, MarshallProtocl.com
When I started Benicar [which lowers 1,25-D], my mood went way up as stress and anxiety went down. Felt like my brain had a big pressure load removed with the Benicar, and I mellowed right out. I have seen a number of people say that their moods improved tremendously when they started the Benicar.
Penny, MarshallProtocol.com