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Non-MP antibiotics under special circumstances

For reasons ranging from prophylaxis to acute infections, Marshall ProtocolA curative medical treatment for chronic inflammatory disease. Based on the Marshall Pathogenesis. (MP) are sometimes advised to take an antibiotic different from the ones used on the MP. If possible, patients ought to verify with their doctor:

  • they have a bacterial illness; this can be done via a culture
  • (if the antibiotic is prescribed as a prophylaxis) that the MP antibiotics wouldn't suffice

Patients are advised not to take additional doses of MP antibiotics as this can have a synergistic effect. Instead, if a patient must take an antibiotic, fluoroquinolones are recommended and are the preferred the non-MP antibiotic. Fluoroquinolones do not target the same bacteria as the MP antibiotics. Use of the drugs, does not preclude an MP patient from continuing with the MP antibiotics and olmesartanMedication taken regularly by patients on the Marshall Protocol for its ability to activate the Vitamin D Receptor. Also known by the trade name Benicar. – unlike other antibiotics.

The number of patients reporting experiences with non-MP antibiotics is limited, but several patients have reported successfully using a fluoroquinolone. Patients must, of course, with their physician to determine the correct course of action.

Verify the diagnosis

If one's doctor has ordered a short course of a non-MP antibiotic because of a suspected infection, first verify that it is an acute bacterial – not viral – infection and that another antibiotic is necessary.

Immunopathologic symptoms may appear very similar to symptoms of infection, especially in the area of ears, throat and sinuses. In most cases, there is time to do a culture to verify the diagnosis and select the correct antibiotic.

Urgent or emergency situations

Related article: Hospitals and emergencies

In the case of an obvious acute bacterial infection or in an emergency situation, patients should:

Be alert for a potential immune system reaction and treat symptoms as they arise.

Prophylactic antibiotics

Related articles: Working with a dentist, Surgery

Dentists and surgeons sometimes order a brief course of an antibiotic before a procedure. Verify that this is essential. Ask your doctor if the current MP antibiotics you are taking would suffice to prevent infection.

Generally speaking, patients should strive to avoid the beta-lactam antibiotics such as amoxicillin, which give unpredictable, and sometimes severe, reactions once a patient's immune system is functioning properly after having been on the MP.

Danger of taking additional MP antibiotics

Sometimes a physician will prescribe a Marshall Protocol (MP) antibiotic such as clindamycinBacteriostatic antibiotic used by patients on the Marshall Protocol. , any of the sulfanomides such as Bactrim DSSulfa antibiotic used by patients on the Marshall Protocol. Combination of sulfamethoxazole and trimethoprim. Works by blocking bacterial folic acid synthesis., or azithromycin (Zithromax) as a prophylactic measure without understanding how taking more than the MP-recommended dose can affect immunopathologyA temporary increase in disease symptoms experienced by Marshall Protocol patients that results from the release of cytokines and endotoxins as disease-causing bacteria are killed..

Of these medications, taking high doses of azithromycinBacteriostatic antibiotic used by Marshall Protocol patients. Has relatively long half-life. would be particularly problematic for the following reasons:

  • relative long half-life
  • most effective MP antibiotic against intracellular bacteria
  • does not have a dose-dependent immunosuppressive effect

In order to convince a doctor not to prescribe them additional MP antibiotics, some patients have simply said they are allergic to these antibiotics. Although patients technically are not allergic to MP antibiotics, this may be the easiest explanation for a doctor to understand and accept.

Fluoroquinolones are the preferred non-MP antibiotics

Main article: Fluoroquinolones

While there are several reasons why the class of antibiotics known as the fluoroquinolones are not recommended as a part of the Marshall Protocol, for short-term use, the drugs may offer the best option for patients who need a non-MP antibiotic.

Because fluoroquinolones do not target intracellular bacteria as do the MP antibiotics, they do not work synergistically with the MP antibiotics.1 This allows MP patients to continue with olmesartan (Benicar)Medication taken regularly by patients on the Marshall Protocol for its ability to activate the Vitamin D Receptor. and the MP antibiotics. It also gives patients the option to use olmesartan and/or minocyclineBacteriostatic antibiotic used by Marshall Protocol patients. to control their immunopathological reactionA temporary increase in disease symptoms experiences by Marshall Protocol patients that results from the release of cytokines and endotoxins as disease-causing bacteria are killed..

One example of what appears to be a relatively well-tolerated cephalosporin is claforan (Cefotaxime).

Managing immunopathology

Patients who take a non-MP antibiotic and see their symptoms increase should consider their reaction immmunopathology and should consider using the same strategies they would typically use to decrease any intolerable reactions – unless, of course, the patient is no longer on olmesartan (Benicar). Patients should consult with their physician to determine which strategies are most effective.

Resuming the MP after taking a non-MP antibiotic

Patients who have taken non-MP antibiotics for a period can resume olmesartan 48 hours after the last dose of the non-MP antibiotic unless they have been taking azithromycin, in which case they must wait two weeks before resuming olmesartan.

Patients should wait 24-48 hours before resuming minocycline in case there are any intolerable adjustment symptoms due to the reintroduction of the olmesartan.

Patients who took non-MP antibiotics for only a day or two may resume minocycline at the previous dose. For those whose non-MP antibiotic course was longer, restart minocycline at a lower dose to avoid a strong immue system reaction.

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References

Last modified: 06.02.2010
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