Acute infections

Measles may protect kids against allergies

http://www.reuters.com/article/healthNews/idUSTRE5236HS20090304

There was no correlation with immunization, just with catching the actual disease. Kids who had been immunized and still caught measles (about 11% of the them) received the same benefit as kids who had never been immunized. The disease was what modified the allergies

..Trevor..

I think the way the Th1 inflammationThe complex biological response of vascular tissues to harmful stimuli such as pathogens or damaged cells. It is a protective attempt by the organism to remove the injurious stimuli as well as initiate the healing process for the tissue. initially overpowers the immune system, is that the level of infection gets to a critical value, and then an incident occurs (eg, sun-holiday, pregnancy, acute infection) which causes extra 1,25-DPrimary biologically active vitamin D hormone. Activates the vitamin D nuclear receptor. Produced by hydroxylation of 25-D. Also known as 1,25-dihydroxycholecalciferol, 1,25-hydroxyvitamin D and calcitirol. production, leading to a breakdown of the negative-feedback mechanisms which normally control the 1,25-D production in the phagocytes. From that point onwards those control mechanisms are not able to reliably maintain control. The patient enters a “relapsing-remitting” phase of the disease process.

Additionally, the TACO membrane protein, through which Mycobacteria infect the phagocyte (and possibly L-formsDifficult-to-culture bacteria that lack a cell wall and are not detectable by traditional culturing processes. Sometimes referred to as cell wall deficient bacteria. too), is down-regulated by VDRThe Vitamin D Receptor. A nuclear receptor located throughout the body that plays a key role in the innate immune response.. So the actual entry of the bacteria into the phagocyte may be facilitated by excess ingested 25-DThe vitamin D metabolite widely (and erroneously) considered best indicator of vitamin D "deficiency." Inactivates the Vitamin D Nuclear Receptor. Produced by hydroxylation of vitamin D3 in the liver. or Vitamin D causing the VDR to shut down. http://tinyurl.com/nkb7x

Cholesterol is also involved in the expression of TACO: http://tinyurl.com/l8rzj

..Trevor..

It may be more complicated than this, but perhaps one way of looking at it might be – if you are very ill, you don't ever get colds (I was at this stage at one time), then if you improve to moderately ill, you get colds fairly often, and then when you are really well, you don't get them hardly at all (perhaps the immune system is so strong it wipes them out before they even multiply enough to produce any noticeable immune reaction). And then it just depends on where you start when entering the MP, whether you get more or less colds.

I think that the ultimate endpoint for us all when we get really well is to not get colds at all (hope so, anyway)

Joyce Waterhouse, PhD

Bacteriality quote:
For decades, researchers working with L-form bacteriaDifficult-to-culture bacteria that lack a cell wall and are not detectable by traditional culturing processes. Sometimes referred to as cell wall deficient bacteria. have warned that while standard antibiotic therapy successfully kills classical bacterial forms, it leaves bacteria that transform into the L-formDifficult-to-culture bacteria that lack a cell wall and are not detectable by traditional culturing processes. Sometimes referred to as cell wall deficient bacteria. unscathed. In fact, when the beta-lactam antibiotics are administered to patients with acute infection, they actually foster the growth of L-form bacteria, meaning that patients treated with these antibiotics can certainly plan on dealing with numerous symptoms of chronic disease in the years to come.

Because L-form bacteria grow so slowly, few researchers have made the connection between acute infection and chronic symptoms that rear their heads decades down the road. However, several research teams have finally taken note of the fact that food poisoning victims, who at one point suffered from a severe acute infection, are much more likely to develop chronic symptoms later in life.

“It’s a dirty little secret of food poisoning,” says Lauren Neergaard of Yahoo News. “E. coli and certain other foodborne illnesses can sometimes trigger serious health problems months or years after patients survived that initial bout. Scientists only now are unraveling a legacy that has largely gone unnoticed.”

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Measles makes the cells more susceptible to a secondary infection

Measles Virus-induced Immunosuppression

“MV infection, while inducing lifelong immunity, also suppresses the immune system leading to an increase in susceptibility to other, secondary infections (24, 67, 91). In vitro research has shown that MV infection of cell cultures makes the cells more susceptible to a secondary bacterial invasion (13) ”