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--- home:alternate:spontaneous_remission [10.19.2018] – [Research with insufficient follow up] sallieq
+++ home:alternate:spontaneous_remission [10.19.2018] – [How is the Marshall Protocol different?] sallieq
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 Researchers at Jefferson Medical Center in Philadelphia found a 74% relapse rate in sarcoidosis patients with treatment-induced remission, while only 60% of patients identified as having a favorable prognosis actually sustained remission over 130 months.(({{pubmed>long:9118698}}))
-Many argue that the most accurate study of sarcoidosis to date is the 2003 NIH ACCESS study, which followed 215 sarcoidosis patients for two years - a period during which it is sometimes mistakenly thought that the disease can go into remission. The study found that measures of sarcoidosis severity remained unchanged over the two-year period, despite the fact that many patients were using corticosteroids and other drugs.
+Many argue that the most accurate study of sarcoidosis to date is the 2003 NIH ACCESS study, which followed 215 sarcoidosis patients for two years - a period during which it is sometimes mistakenly thought that the disease can go into remission. The study found that measures of sarcoidosis severity remain unchanged over the two-year period, despite the fact that many patients were using corticosteroids and other drugs.
 In fact, in the NIH ACCESS study there were no documented cases of spontaneous remission. Even in the positive-sounding “improved” category for clinical markers, the percentages described were at best “improved”, not "substantially better" and certainly not "cured." An indication of lack of substantial improvement in the improved group is the fact that there were essentially no change in use of corticosteroid therapy during the two year period. The study also concluded that most patients with persistent sarcoidosis at two years were “unlikely to have resolution of the illness” and that "end-stage pulmonary sarcoidosis usually develops over one or two decades."
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 A [[http://www.wired.com/medtech/health/news/2005/03/66806|2005 article]] on gene therapy described patients who had undergone treatment as “basically cured” – even though three had developed leukemia and one died.
-The above example is a misuse of the word “cure.” For one thing, an actual cure results from a treatment that allows all participants to become well, no side effects or long-term harm included. Did the above study check in with its subjects a decade down the road in order to access their health years later? Probably not. But if they did, the subjects were probably symptomatic again, as gene therapy has not yet been adopted as an effective way to treat disease.
+The above example is a misuse of the word “cure.” For one thing, an actual cure results from a treatment that allows all participants to become well, including no long-term side effects or harm. Did the above study check in with its subjects a decade down the road in order to access their health years later? Probably not. But if they did, the subjects were probably symptomatic again, as gene therapy has not yet been adopted as an effective way to treat disease.
 The public often isn’t satisfied with the medical community’s perception of a “cure,” which is why so many patients have left mainstream medicine – searching for solutions among doctors that practice alternative medicine or even among psychotherapists.
-Unfortunately, for chronically ill patients, commercial culture and the media have combined to progressively define down what “better” means—so much so that assessing the significance of any new “breakthrough” becomes difficult, at best.
+Unfortunately, for chronically ill patients, commercial interests and the media have combined to progressively define down what “better” means—so much so that assessing the significance of any new “breakthrough” becomes difficult, at best.
 ===== How is the Marshall Protocol different? =====
-The MP is different. It is an attempt to address the underlying cause of Th1 disease – the bacteria causing symptoms in the first place. And unless these bacteria are targeted and killed, Th1 diseases do not go away. Indeed, if they went away on their own, why would there be hundreds of forums on the Internet where people with chronic disease discuss what it’s like to live a life full of relapses and pain?
+The MP is different. It is an attempt to address the underlying cause of Th1 disease – failure of the innate immune system to control bacteria which caused the symptoms in the first place. Unless these bacteria are targeted and killed, Th1 diseases do not go away. Indeed, if they went away on their own, why would there be hundreds of forums on the Internet where people with chronic disease discuss what it’s like to live a life full of relapses and pain?
+===== Common misperceptions =====
 {{tag>Alternate_models}}

home/alternate/spontaneous_remission.txt · Last modified: 09.14.2022 by 127.0.0.1