Vitamin D metabolite calculator

Recent research, including work done by the Autoimmunity Research Foundation research team, has shown that the Vitamin D nuclear receptor plays a key role in chronic and inflammatory disease. The VDR's transcription of genes is controlled in turn by the Vitamin D metabolism, which is progressively inhibited as the Th1 metagenomic microbiota gradually accumulates in the body's nucleated cells.

Below is an algorithm which will give physicians insight into how the most common Vitamin D metabolites can indicate disease status. This interpretation is not intended as any form of medical diagnosis; the physician must also take into account the general patient presentation and workup, and other objective measures of illness. This algorithm is based on research published in several papers and presentations.1) 2) 3) 4) 5)

1. Has the patient taken certain other drugs in the last 60 days including corticosteroids, other immunosuppressants (e.g. TNF-alpha drugs), or high-dose antibiotics.

2. Has the patient begun taking olmesartan (Benicar)?


Marshall TG. Vitamin D discovery outpaces FDA decision making. Bioessays. 2008 Feb;30(2):173-82. doi: 10.1002/bies.20708.
[PMID: 18200565] [DOI: 10.1002/bies.20708]
Albert PJ, Proal AD, Marshall TG. Vitamin D: the alternative hypothesis. Autoimmun Rev. 2009 Jul;8(8):639-44. doi: 10.1016/j.autrev.2009.02.011. Epub 2009 Feb 12.
[PMID: 19393200] [DOI: 10.1016/j.autrev.2009.02.011]
Blaney G, et al. In press. Vitamin D Metabolites as Clinical Markers in Autoimmune and Chronic Disease. Annals of NY Academy of Sciences.
Blaney G. Vitamin D Metabolites as Clinical Markers in Autoimmune and Chronic Illness. International Congress on Autoimmunity, Porto, 2008.
Perez T. MP Study Results. International Congress on Autoimmunity, Porto, 2008.
home/tests/vitdinterpretation.txt · Last modified: 09.14.2022 by
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