This shows you the differences between two versions of the page.
Both sides previous revisionPrevious revisionNext revision | Previous revisionNext revisionBoth sides next revision | ||
home:arf:040909 [06.25.2009] – paulalbert | home:arf:040909 [01.23.2011] – paulalbert | ||
---|---|---|---|
Line 1: | Line 1: | ||
+ | ====== Press release – Vitamin D may exacerbate autoimmune disease ====== | ||
+ | **April 15, 2009** – Deficiency in vitamin D has been widely regarded as contributing to autoimmune disease, but a review appearing in // | ||
+ | |||
+ | Authored by a team of researchers at the California-based non-profit Autoimmunity Research Foundation, the paper goes on to point out that molecular biologists have long known that the form of vitamin D derived from food and supplements, | ||
+ | |||
+ | The insights are based on molecular research showing that 25-D inactivates, | ||
+ | |||
+ | Written under the guidance of Professor Trevor Marshall of Murdoch University, Western Australia, the paper contends that 25-D's actions must be considered in light of recent research on the Human Microbiome. Such research shows that bacteria are far more pervasive than previously thought--90% of cells in the body are estimated to be non-human--increasing the likelihood that autoimmune diseases are caused by persistent pathogens, many of which have yet to be named or have their DNA characterized. | ||
+ | |||
+ | Marshall and team explain that by deactivating the VDR and subsequently the immune response, 25-D lowers the inflammation caused by many of these bacteria, but allows them to spread more easily in the long-run. They outline how long-term harm caused by high levels of 25-D has been missed because the bacteria implicated in autoimmune disease grow very slowly. For example, a higher incidence in brain lesions, allergies, and atopy in response to vitamin D supplementation have been noted only after decades of supplementation with the secosteroid. | ||
+ | |||
+ | Furthermore, | ||
+ | |||
+ | The team points out the importance of examining alternate models of vitamin D metabolism. " | ||
+ | |||
+ | For the past five years, Autoimmunity Research Foundation has been running an observational study in which patients are administered pulsed, low-dose antibiotics and a VDR agonist in order to kill chronic bacteria implicated in their diseases. Specific data on the cohort was recently presented by Capt. Thomas H. Perez, USPHS (ret), at the International Congress on Autoimmunity in Porto, Portugal: | ||
+ | * Transcript: http:// | ||
+ | * Video: http:// | ||
+ | |||
+ | |||
+ | |||
+ | |||
+ | ===== Resources ===== | ||
+ | |||
+ | * Citation: Albert PJ et al. In press. Autoimmunity Reviews. " | ||
+ | * Full-text preprint: http:// | ||
+ | * DOI: http:// |