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home:arf:timeline [02.14.2019] – [Notes and comments] sallieqhome:arf:timeline [02.14.2019] – [Notes and comments] sallieq
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 **1999** – Marshall learns that other patients with sarcoidosis who were administered Angiotensin Receptor Blockers (ARBs) often developed a neurological reaction. Marshall starts a sabbatical in early 2001 in order to further investigate this reaction. **1999** – Marshall learns that other patients with sarcoidosis who were administered Angiotensin Receptor Blockers (ARBs) often developed a neurological reaction. Marshall starts a sabbatical in early 2001 in order to further investigate this reaction.
  
-**2001** - Marshall submits paper explaining that sarcoidosis could have a bacterial pathogenesis. Three revisions of the paper are rejected by the journal "Sarcoidosis, Vasculitis and Diffuse Lung Diseases"  as having no potential interest for its readers. +**2001** - Marshall submits paper explaining that sarcoidosis could have a bacterial pathogenesis. Three revisions of the paper are rejected by the journal //Sarcoidosis, Vasculitis and Diffuse Lung Diseases//  as having no potential interest for its readers. 
  
 **2001 March** - The first early adopter, Elaine Emmi, begins the use of an ARB to treat her sarcoidosis. **2001 March** - The first early adopter, Elaine Emmi, begins the use of an ARB to treat her sarcoidosis.
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 **2001 December** - Nilsson //et al.// publish article in //Journal of infectious disease// showing that deceased sarcoidosis patients contain the genetic material from //Rickettsia helvetica// in the cytoplasm of cells within sarcoid granuloma.(({{pubmed>long:11930323}})) Marshall commences using pulsed, sub-inhibitory, doses of antibiotics in an attempt to reverse his sarcoidosis. **2001 December** - Nilsson //et al.// publish article in //Journal of infectious disease// showing that deceased sarcoidosis patients contain the genetic material from //Rickettsia helvetica// in the cytoplasm of cells within sarcoid granuloma.(({{pubmed>long:11930323}})) Marshall commences using pulsed, sub-inhibitory, doses of antibiotics in an attempt to reverse his sarcoidosis.
  
-**2002 March** –  Marshall registers [[http://sarcinfo.com|Sarcinfo.com]], a forum-based website where patients sick with sarcoidosis begin to discuss a novel antibacterial therapy for the disease.+**2002 March** –  Marshall registers "//Sarcinfo.com//", a forum-based website where patients sick with sarcoidosis begin to discuss a novel antibacterial therapy for the disease.
  
 **2002 May** –  Marshall changes to using the ARB olmesartan medoxomil (Benicar).  **2002 May** –  Marshall changes to using the ARB olmesartan medoxomil (Benicar). 
  
-**2002 August** – Trevor Marshall and Frances (Liz) Marshall publish NetPrint, "[[http://clinmed.netprints.org/cgi/content/full/2002080006|Valsartan Dosing Regime Modulates Psychotic Events in Two Sarcoidosis Patients]]." The case report shares early observations that valsartan (Diovan) induced hallucinations and psychedelic dreams. Convinced that they have developed a pathogenic description of sarcoidosis, they write the Netprint "[[http://clinmed.netprints.org/cgi/content/full/2002080004|Remission in Sarcoidosis]]"+**2002 August** – Trevor Marshall and Frances (Liz) Marshall publish NetPrint, "//Valsartan Dosing Regime Modulates Psychotic Events in Two Sarcoidosis Patients//". The case report shares early observations that valsartan (Diovan) induced hallucinations and psychedelic dreams. Convinced that they have developed a pathogenic description of sarcoidosis, they write the Netprint "//Remission in Sarcoidosis//"
  
-**2002 September** – "[[http://clinmed.netprints.org/cgi/content/full/2002080004|Remission in Sarcoidosis]]" is published (in summary) at Mercola.com. Later that month, early adopter (and colleague) Belinda Fenter commences pulsed minocycline.+**2002 September** –  //Remission in Sarcoidosis// is published (in summary) at Mercola.com. Later that month, early adopter (and colleague) Belinda Fenter commences pulsed minocycline.
  
 **2002 December** – Early adopter (and colleague) Meg Mangin commences pulsed tetracycline.  **2002 December** – Early adopter (and colleague) Meg Mangin commences pulsed tetracycline. 
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  Seperately, images from Emil Wirostko's group(({{pubmed>long:15043554}})) (({{pubmed>long:8622416}})) (({{pubmed>long:7892050}})) finally confirmed that a cytoplasmic microbiota of intraphagocytic, L-form bacteria must drive the biochemical changes observed in sarcoidosis.  Seperately, images from Emil Wirostko's group(({{pubmed>long:15043554}})) (({{pubmed>long:8622416}})) (({{pubmed>long:7892050}})) finally confirmed that a cytoplasmic microbiota of intraphagocytic, L-form bacteria must drive the biochemical changes observed in sarcoidosis.
  
-**2003 January** – Mangin changes to minocycline and commences concurrent olmesartan. Fenter also commences using olmesartan. They are joined by Ms. Dale Thurlow, and Marshall's Protocol has taken root. Later that month Trevor Marshall and Frances (Liz) Marshall publish "[[http://clinmed.netprints.org/cgi/content/full/2003010001|New Treatments Emerge as Sarcoidosis Yields Up its Secrets]]" on Clinmed, after it is savaged by two pulmonologist peer-reviewers for "BMC Pulmonary Medicine"+**2003 January** – Mangin changes to minocycline and commences concurrent olmesartan. Fenter also commences using olmesartan. They are joined by Ms. Dale Thurlow, and Marshall's Protocol has taken root. Later that month Trevor Marshall and Frances (Liz) Marshall publish "New Treatments Emerge as Sarcoidosis Yields Up its Secrets" on Clinmed, after it is savaged by two pulmonologist peer-reviewers for "BMC Pulmonary Medicine"
  
 **2004 April** – Autoimmunity Research Foundation is founded. **2004 April** – Autoimmunity Research Foundation is founded.
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 **2004 July** – Marshall registers [[http://marshallprotocol.com|MarshallProtocol.com]], a website where patients sick with a range of chronic diseases discuss an antibacterial therapy since named the "Marshall Protocol." – Aussie Barb joins MarshallProtocol.com and begins to perform an invaluable behind-the-scenes role on the study site. **2004 July** – Marshall registers [[http://marshallprotocol.com|MarshallProtocol.com]], a website where patients sick with a range of chronic diseases discuss an antibacterial therapy since named the "Marshall Protocol." – Aussie Barb joins MarshallProtocol.com and begins to perform an invaluable behind-the-scenes role on the study site.
  
-**2004 December** - The Journal of the Interregional Clinical-Diagnostic Center, Kazan, Russia, (ISSN: 1726-6149) publishes, in Russian translation, Marshall's paper "[[http://www.joimr.org/phorum/read.php?f=2&i=107&t=107|Antibacterial Therapy Induces Remission in Sarcoidosis]]" in its special issue on Sarcoidosis. +**2004 December** - [[http://www.joimr.org/|joimr]] The Journal of the Interregional Clinical-Diagnostic Center, Kazan, Russia, (ISSN: 1726-6149) publishes, in Russian translation, Marshall's paper "//Antibacterial Therapy Induces Remission in Sarcoidosis//" in its special issue on Sarcoidosis. 
  
 **2005 March ** – ARF's 'Recovering from Chronic Disease' conference held in Chicago. Notable speakers include Lida Mattman PhD and Dr. Andrew Wright. **2005 March ** – ARF's 'Recovering from Chronic Disease' conference held in Chicago. Notable speakers include Lida Mattman PhD and Dr. Andrew Wright.
  
-**2005 June** - Marshall publishes the English text of the Russian paper "[[http://www.joimr.org/phorum/read.php?f=2&i=107&t=107|Antibacterial Therapy Induces Remission in Sarcoidosis]]"+**2005 June** - Marshall publishes the English text of the Russian paper "//Antibacterial Therapy Induces Remission in Sarcoidosis//" [[http://www.joimr.org/|joimr]]
  
 **2005 July** – Marshall files for [[http://www.freepatentsonline.com/y2006/0025358.html|patent]] with US Patent and Trademark Office (eventually published in February 2006) which explains a method of killing the stealthy intracellular bacteria which cause many Th1 and "autoimmune" diseases. A [[http://www.freepatentsonline.com/y2007/0135504.html|second patent]] which specifies a broader range of chronic diseases is filed in December 2006. **2005 July** – Marshall files for [[http://www.freepatentsonline.com/y2006/0025358.html|patent]] with US Patent and Trademark Office (eventually published in February 2006) which explains a method of killing the stealthy intracellular bacteria which cause many Th1 and "autoimmune" diseases. A [[http://www.freepatentsonline.com/y2007/0135504.html|second patent]] which specifies a broader range of chronic diseases is filed in December 2006.
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 ===== Notes and comments ===== ===== Notes and comments =====
  
-broken links+//broken links//
 "[[http://catalogue.library.uwa.edu.au/search/?searchtype=X&searcharg=marshall+and+Trevor&searchscope=5&SORT=AZ&extended=0&SUBMIT=Search&searchlimits=&searchorigarg=Xmarshall+and+Trevor%26SORT%3DA|Modelling and simulation in diabetes care]] "[[http://catalogue.library.uwa.edu.au/search/?searchtype=X&searcharg=marshall+and+Trevor&searchscope=5&SORT=AZ&extended=0&SUBMIT=Search&searchlimits=&searchorigarg=Xmarshall+and+Trevor%26SORT%3DA|Modelling and simulation in diabetes care]]
  
 //[[http://www.sarcoidosis.it/home.html|Sarcoidosis, Vasculitis and Diffuse Lung Diseases]]// //[[http://www.sarcoidosis.it/home.html|Sarcoidosis, Vasculitis and Diffuse Lung Diseases]]//
  
 +[[http://clinmed.netprints.org/cgi/content/full/2002080006|Valsartan Dosing Regime Modulates Psychotic Events in Two Sarcoidosis Patients]]
  
 +[[http://clinmed.netprints.org/cgi/content/full/2002080004|Remission in Sarcoidosis]]
 +[[http://sarcinfo.com|Sarcinfo.com]]
 +"[[http://clinmed.netprints.org/cgi/content/full/2002080004|Remission in Sarcoidosis]]" 
 +
 +"[[http://clinmed.netprints.org/cgi/content/full/2003010001|New Treatments Emerge as Sarcoidosis Yields Up its Secrets]]" 
 +
 +[[http://www.joimr.org/phorum/read.php?f=2&i=107&t=107|Antibacterial Therapy Induces Remission in Sarcoidosis]]
  
  
home/arf/timeline.txt · Last modified: 09.14.2022 by 127.0.0.1
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