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home:diseases:aging [01.19.2019] – [Notes and comments] sallieqhome:diseases:aging [01.26.2019] – [defunct cells] sallieq
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   * **Cellular theory** – According to this theory, the normal body has a finite potential to replicate and maintain functional capacity (Hayflick limit).   * **Cellular theory** – According to this theory, the normal body has a finite potential to replicate and maintain functional capacity (Hayflick limit).
  
 +==== Breaking up defunct cells ====
  
 +[[https://www.ebiomedicine.com/article/S2352-3964(18)30629-7/fulltext|Article in Press
 +Senolytics in idiopathic pulmonary fibrosis]]  (({{pubmed>long:30616998}})) 
 +<blockquote>
 + Selectively ablating senescent cells using dasatinib plus quercetin (DQ) alleviates IPF-related dysfunction in bleomycin-administered mice.
 +
 +Our first-in-humans open-label pilot supports study feasibility and provides initial evidence that senolytics may alleviate physical dysfunction in IPF  (({{pubmed>long:30616998}})).</blockquote>
 ===== Diseases of the aging are chronic diseases ===== ===== Diseases of the aging are chronic diseases =====
  
home/diseases/aging.txt · Last modified: 09.14.2022 by 127.0.0.1
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