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====== Baldness (alopecia) ====== | ====== Baldness (alopecia) ====== | ||
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+ | ===== Introduction ===== | ||
__In search of the "hair cycle clock": | __In search of the "hair cycle clock": | ||
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===== Members' | ===== Members' | ||
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- | Balding in 20s linked to doubled risk of prostate cancer | + | |
- | Share698(2) | + | |
- | By Thomas H. Maugh II, Los Angeles Times | + | |
- | February 16, 2011, 9:40 a.m. | + | |
Men who go bald in their early 20s have a doubled risk of developing prostate cancer, but those who lose hair in their 30s and 40s apparently are not at greater risk, French researchers reported Tuesday. The findings suggest that men who lose their hair very early in life might benefit from increased screening. | Men who go bald in their early 20s have a doubled risk of developing prostate cancer, but those who lose hair in their 30s and 40s apparently are not at greater risk, French researchers reported Tuesday. The findings suggest that men who lose their hair very early in life might benefit from increased screening. | ||
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===== Role of vitamin D ===== | ===== Role of vitamin D ===== | ||
- | Dermatol Online J. 2010 Feb 15;16(2):3. | ||
- | Does D matter? The role of vitamin D in hair disorders and hair follicle cycling. | ||
- | Amor KT, Rashid RM, Mirmirani P. | ||
- | Department of Dermatology, | + | BACKGROUND: The role of vitamin D in the proliferation and differentiation of keratinocytes is well known within the field of dermatology. OBJECTIVE: We sought to evaluate the role that vitamin D and the vitamin D receptor play in the hair cycle and assess how this can be clinically applied to the treatment of hair disorders. |
- | BACKGROUND: The role of vitamin D in the proliferation and differentiation of keratinocytes is well known within the field of dermatology. OBJECTIVE: We sought to evaluate the role that vitamin D and the vitamin D receptor play in the hair cycle and assess how this can be clinically applied to the treatment of hair disorders. | + | |
- | < | + | METHODS: A MEDLINE search (1955-July 2009) was preformed to find relevant articles pertaining to vitamin D, the vitamin D receptor, and hair loss. RESULTS: The vitamin D receptor, independent of vitamin D, plays an important role in hair cycling, specifically anagen initiation. The role of vitamin D in hair follicle cycling is not as well understood. |
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- | The hair cycle and Vitamin D receptor. (({{pubmed> | + | LIMITATIONS: |
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+ | From: Bane, date: 2011-10-20 [[https:// | ||
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The Vitamin D receptor (VDR) plays a critical role in epidermal homeostasis. The ligand-dependent actions of the VDR attenuate epidermal keratinocyte proliferation and promote keratinocyte differentiation. Calcium can compensate for the absence of the VDR in maintaining a normal program of epidermal keratinocyte differentiation both in vitro and in vivo. In contrast, the effects of VDR ablation on the hair follicle cannot be prevented by maintaining normal calcium levels and are independent of 1, | The Vitamin D receptor (VDR) plays a critical role in epidermal homeostasis. The ligand-dependent actions of the VDR attenuate epidermal keratinocyte proliferation and promote keratinocyte differentiation. Calcium can compensate for the absence of the VDR in maintaining a normal program of epidermal keratinocyte differentiation both in vitro and in vivo. In contrast, the effects of VDR ablation on the hair follicle cannot be prevented by maintaining normal calcium levels and are independent of 1, | ||
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