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home:diseases:anemia [06.28.2014] – [Management] jjhome:diseases:anemia [01.06.2019] – [Anemia] sallieq
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 ====== Anemia ====== ====== Anemia ======
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 +<relatedarticle> [[home:diseases:cfs|Chronic fatigue syndrome]] </article>
 +===== Introduction =====
 +
  
 Anemia of chronic disease, also referred to as anemia of inflammatory response, is a common condition seen in chronic illness.(({{pubmed>long:7719246}})) Anemia is not due to iron deficiency, nor will it be helped by iron supplements. In fact, iron supplements are counterproductive because iron is "crucial" to the survival and multiplication of pathogens.(({{pubmed>long:21414421}})) Anemia of chronic disease, also referred to as anemia of inflammatory response, is a common condition seen in chronic illness.(({{pubmed>long:7719246}})) Anemia is not due to iron deficiency, nor will it be helped by iron supplements. In fact, iron supplements are counterproductive because iron is "crucial" to the survival and multiplication of pathogens.(({{pubmed>long:21414421}}))
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   * **total iron binding capacity (TIBC)** – Shows if there is the "right amount" of iron in the blood. TIBC helps measure the ability of transferrin to carry iron in the blood. TIBC is typically measured along with serum iron to evaluate people suspected of having either iron deficiency or iron overload. The iron concentration divided by TIBC gives the transferrin saturation, which is a more useful indicator of iron status than iron or TIBC alone. The TIBC test measures the amount of iron that the blood would carry if the transferrin were fully saturated. Since transferrin is produced by the liver, the TIBC can be used to monitor liver function and nutrition. Described further [[http://www.labtestsonline.org/understanding/analytes/tibc/test.html|here]].   * **total iron binding capacity (TIBC)** – Shows if there is the "right amount" of iron in the blood. TIBC helps measure the ability of transferrin to carry iron in the blood. TIBC is typically measured along with serum iron to evaluate people suspected of having either iron deficiency or iron overload. The iron concentration divided by TIBC gives the transferrin saturation, which is a more useful indicator of iron status than iron or TIBC alone. The TIBC test measures the amount of iron that the blood would carry if the transferrin were fully saturated. Since transferrin is produced by the liver, the TIBC can be used to monitor liver function and nutrition. Described further [[http://www.labtestsonline.org/understanding/analytes/tibc/test.html|here]].
   * **soluble transferrin receptor (sTfR)** – Relatively new test. While standard measures of iron status such as ferritin, total iron-binding capacity, and serum iron are directly affected by chronic disease sTfR is elevated in iron deficiency but is not appreciably affected by chronic disease. A good way to verify anemia of chronic desease because it is not affected by inflammation. Should be considered for anemic patients whose differential diagnosis includes iron deficiency and anemia of inflammatory disease.    * **soluble transferrin receptor (sTfR)** – Relatively new test. While standard measures of iron status such as ferritin, total iron-binding capacity, and serum iron are directly affected by chronic disease sTfR is elevated in iron deficiency but is not appreciably affected by chronic disease. A good way to verify anemia of chronic desease because it is not affected by inflammation. Should be considered for anemic patients whose differential diagnosis includes iron deficiency and anemia of inflammatory disease. 
-  * **hemoglobin** – The iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates. The effect of locking up iron stores is to reduce the ability of the bone marrow to produce red blood cells. These cells require iron for their massive amounts of hemoglobin which allow them to transport oxygen. +  * **hemoglobin  (HGB)** – The iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates. The effect of locking up iron stores is to reduce the ability of the bone marrow to produce red blood cells. These cells require iron for their massive amounts of hemoglobin which allow them to transport oxygen. 
-  * **hematocrit** – A measure of the number of red blood cells and the size of red blood cells. It gives a percentage of red blood cells found in whole blood. Most automated cell counters measure the hemoglobin directly, but the hematocrit is calculated. Generally, therefore, it is probably more reliable to base clinical decisions on the hemoglobin concentration.+  * **hematocrit  (HCT)** – A measure of the number of red blood cells and the size of red blood cells. It gives a percentage of red blood cells found in whole blood. Most automated cell counters measure the hemoglobin directly, but the hematocrit is calculated. Generally, therefore, it is probably more reliable to base clinical decisions on the hemoglobin concentration.
   * **erythropoietin (EPO)** – Erythropoietin is not a routine test. It is ordered primarily to help differentiate between different types of anemia and to determine whether the amount of erythropoietin being produced is appropriate for the level of anemia present. Low EPO in patients on olmesartan might largely be due to better blood flow and oxygenation in kidneys since the olmesartan blocks the angiotensin II receptors. This would have an effect superimposed on anemia of chronic disease which is caused by immunopathology.   * **erythropoietin (EPO)** – Erythropoietin is not a routine test. It is ordered primarily to help differentiate between different types of anemia and to determine whether the amount of erythropoietin being produced is appropriate for the level of anemia present. Low EPO in patients on olmesartan might largely be due to better blood flow and oxygenation in kidneys since the olmesartan blocks the angiotensin II receptors. This would have an effect superimposed on anemia of chronic disease which is caused by immunopathology.
    
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 Once I started thyroxine my life turned around, as I got most of my energy back and my thinning hair started growing back - but my arthritis was as bad as ever. Once I started thyroxine my life turned around, as I got most of my energy back and my thinning hair started growing back - but my arthritis was as bad as ever.
  
-Fast forward 1 year - I found the MP and began phase one. Within days of starting mino I began to experience a metallic taste in my mouth. Could that metallic taste be ... metal?  Can't prove it, but my ferritin levels shot through the roof! You can read my phase 1 posts on my thread: http://www.marshallprotocol.com/forum20/5902-1.html+Fast forward 1 year - I found the MP and began phase one. Within days of starting mino I began to experience a metallic taste in my mouth. Could that metallic taste be ... metal?  Can't prove it, but my ferritin levels shot through the roof! You can read my posts on my thread:  https://www.marshallprotocol.com/forum35/7698.html
  
 I reckon all those iron-sequestering CWD monsters were dying and giving up all the iron back into my bloodstream. After a couple of months, my ferritin levels came down to normal again and the metallic taste went away at the same time. I reckon all those iron-sequestering CWD monsters were dying and giving up all the iron back into my bloodstream. After a couple of months, my ferritin levels came down to normal again and the metallic taste went away at the same time.
home/diseases/anemia.txt · Last modified: 09.14.2022 by 127.0.0.1
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