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home:diseases:ankylosing_spondylitis [01.11.2019] – [Doctor's report] sallieqhome:diseases:ankylosing_spondylitis [02.10.2019] – [Evidence of infectious cause] sallieq
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 ==== Standard treatments ==== ==== Standard treatments ====
  
-Injections usually used are seriously immune suppressant +Injections used in standard medical treatment are seriously immune suppressant 
 [[https://medlineplus.gov/druginfo/meds/a608041.html|Certolizumab ]], [[https://medlineplus.gov/druginfo/meds/a603010.html|Adalimumab ]], [[https://medlineplus.gov/druginfo/meds/a604023.html|Infliximab]] [[https://medlineplus.gov/druginfo/meds/a608041.html|Certolizumab ]], [[https://medlineplus.gov/druginfo/meds/a603010.html|Adalimumab ]], [[https://medlineplus.gov/druginfo/meds/a604023.html|Infliximab]]
  
 +
 +===== Doctor's report on MP treatment =====
 +
 +
 +[[home:publications:blaney_autoimmunity_2010|Blaney: congress on autoimmunity 2010]]
 +
 +
 +<blockquote>
 +Case 1 is ankylosing spondylitis in a now 50 year old male. Onset was at the age of 26, initially as sacroiliitis. It progressed in a typical fashion with increasing rigidity of the spine, fusion of cervical facet joints, pain and fatigue. He also developed co-morbid conditions including chronic prostatitis, neuropathy, irritable bowel syndrome, insomnia and depression. He was unable to work full time.  He started treatment December 2005.
 +
 +He experienced waxing and waning of symptoms both physical and emotional through the first 3 years of treatment, peaking in mid 2007. Presently he is no longer depressed and is back working full time in international finance. His prostatitis has cleared as has his IBS. Bone density increased 11% in his femur and 5% in his lumbar vertebrae over the last 2 years. His Bath Ankylosing spondylitis Disease Activity Index which had risen from 8.8 to 9.2 is now 5.3.</blockquote> 
  
  
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 (({{pubmed>long:11157137}}))</blockquote> (({{pubmed>long:11157137}}))</blockquote>
  
 +[[https://ard.bmj.com/content/76/6/1123.abstract?utm_term=usage-012019&utm_content=consumer&utm_campaign=ard&utm_medium=cpc&utm_source=trendmd|Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis ]]
 ===== Management ===== ===== Management =====
  
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 <blockquote> I was on Fosamax for 2 years, which lead to acid reflux and the need for Prilosec.  My primary doc was obviously wrong then, as I believe he is now when he recommends 1000mg of Vitamin D daily.  Been there and done that already with very bad results.  I don't argue with my doc, but I make my own educated health decisions.  Most of our current medical insight seems to be blinded by the "sunshine vitamin syndrome" //Jasmine//</blockquote> <blockquote> I was on Fosamax for 2 years, which lead to acid reflux and the need for Prilosec.  My primary doc was obviously wrong then, as I believe he is now when he recommends 1000mg of Vitamin D daily.  Been there and done that already with very bad results.  I don't argue with my doc, but I make my own educated health decisions.  Most of our current medical insight seems to be blinded by the "sunshine vitamin syndrome" //Jasmine//</blockquote>
  
-===== Doctor's report ===== 
  
- +==== Related research on osteonecrosis ====
-[[home:publications:blaney_autoimmunity_2010|Blaney: congress on autoimmunity 2010]] +
- +
- +
-<blockquote> +
-Case 1 is ankylosing spondylitis in a now 50 year old male. Onset was at the age of 26, initially as sacroiliitis. It progressed in a typical fashion with increasing rigidity of the spine, fusion of cervical facet joints, pain and fatigue. He also developed co-morbid conditions including chronic prostatitis, neuropathy, irritable bowel syndrome, insomnia and depression. He was unable to work full time.  He started treatment December 2005. +
- +
-He experienced waxing and waning of symptoms both physical and emotional through the first 3 years of treatment, peaking in mid 2007. Presently he is no longer depressed and is back working full time in international finance. His prostatitis has cleared as has his IBS. Bone density increased 11% in his femur and 5% in his lumbar vertebrae over the last 2 years. His Bath Ankylosing spondylitis Disease Activity Index which had risen from 8.8 to 9.2 is now 5.3.</blockquote>  +
- +
-==== Related research ====+
  
 The findings from this study indicated that even short-term oral use of alendronate led to ONJ in a subset of patients after certain dental procedures were performed. These findings have important therapeutic and preventive implications.   (({{pubmed>long:19119168}})) The findings from this study indicated that even short-term oral use of alendronate led to ONJ in a subset of patients after certain dental procedures were performed. These findings have important therapeutic and preventive implications.   (({{pubmed>long:19119168}}))
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 Oral bisphosphonate use and the prevalence of osteonecrosis of the jaw   (({{pubmed>long:30534822}})) Oral bisphosphonate use and the prevalence of osteonecrosis of the jaw   (({{pubmed>long:30534822}}))
  
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-{{tag>diseases arrange}} +{{tag>diseases }}
  
 ===== Notes and comments ===== ===== Notes and comments =====
home/diseases/ankylosing_spondylitis.txt · Last modified: 09.14.2022 by 127.0.0.1
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