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home:diseases:ankylosing_spondylitis [01.11.2019] – sallieq | home:diseases:ankylosing_spondylitis [08.12.2019] – [Headline] sallieq | ||
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====== Ankylosing spondylitis ====== | ====== Ankylosing spondylitis ====== | ||
- | ===== Introduction ===== | + | < |
- | //from// [[https:// | + | |
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A form of arthritis, AS is characterized by chronic inflammation, | A form of arthritis, AS is characterized by chronic inflammation, | ||
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[[https:// | [[https:// | ||
- | ==== Standard treatments | + | ==== Immune suppression |
- | Injections | + | Injections used in standard medical treatment |
[[https:// | [[https:// | ||
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+ | ===== Doctor' | ||
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+ | Case 1 is ankylosing spondylitis in a now 50 year old male. Onset was at the age of 26, initially as sacroiliitis. It progressed in a typical fashion with increasing rigidity of the spine, fusion of cervical facet joints, pain and fatigue. He also developed co-morbid conditions including chronic prostatitis, | ||
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+ | He experienced waxing and waning of symptoms both physical and emotional through the first 3 years of treatment, peaking in mid 2007. Presently he is no longer depressed and is back working full time in international finance. His prostatitis has cleared as has his IBS. Bone density increased 11% in his femur and 5% in his lumbar vertebrae over the last 2 years. His Bath Ankylosing spondylitis Disease Activity Index which had risen from 8.8 to 9.2 is now 5.3.</ | ||
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(({{pubmed> | (({{pubmed> | ||
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===== Management ===== | ===== Management ===== | ||
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The Bath Ankylosing Disease Activity Index remains the gold standard for assessing disease activity in a routine practice, despite poor correlation with C-reactive protein (CRP) levels and MRI inflammation. | The Bath Ankylosing Disease Activity Index remains the gold standard for assessing disease activity in a routine practice, despite poor correlation with C-reactive protein (CRP) levels and MRI inflammation. | ||
- | ==== Headline | + | ==== D-free calcium |
< | < | ||
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- | ==== Related research ==== | + | ==== Related research |
The findings from this study indicated that even short-term oral use of alendronate led to ONJ in a subset of patients after certain dental procedures were performed. These findings have important therapeutic and preventive implications. | The findings from this study indicated that even short-term oral use of alendronate led to ONJ in a subset of patients after certain dental procedures were performed. These findings have important therapeutic and preventive implications. | ||
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Oral bisphosphonate use and the prevalence of osteonecrosis of the jaw | Oral bisphosphonate use and the prevalence of osteonecrosis of the jaw | ||
- | ===== Doctor' | + | |
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- | Case 1 is ankylosing spondylitis in a now 50 year old male. Onset was at the age of 26, initially as sacroiliitis. It progressed in a typical fashion with increasing rigidity of the spine, fusion of cervical facet joints, pain and fatigue. He also developed co-morbid conditions including chronic prostatitis, | + | |
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- | He experienced waxing and waning of symptoms both physical and emotional through the first 3 years of treatment, peaking in mid 2007. Presently he is no longer depressed and is back working full time in international finance. His prostatitis has cleared as has his IBS. Bone density increased 11% in his femur and 5% in his lumbar vertebrae over the last 2 years. His Bath Ankylosing spondylitis Disease Activity Index which had risen from 8.8 to 9.2 is now 5.3.</ | + | |
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===== Notes and comments ===== | ===== Notes and comments ===== |