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--- home:diseases:anxiety [05.02.2011] – external edit 127.0.0.1
+++ home:diseases:anxiety [03.16.2012] – [Patients experiences] paulalbert
@@ Line 18: / Line 18: @@
 //**L.E. Goehler** et al.//(({{pubmed>long:17428636}}))</blockquote>
+Further, Neufeld //et al.// showed that germ-free mice exhibited reduced anxiety-like behavior as well as significant neurochemical changes in the brain compared to mice without an intestinal microbiota.(({{pubmed>long:21054680}}))
-The frequency with which patients of certain Th1 diseases also experience anxiety(({{pubmed>long:8818377}})) (({{pubmed>long:18774427}})) (({{pubmed>long:18774427}})) (({{pubmed>long:9361174}})) (({{pubmed>long:15569892}})) (({{pubmed>long:7883407}})) (({{pubmed>long:9707157}})) (({{pubmed>long:12011605}})) (({{pubmed>long:11391746}})) suggests a single underlying cause.
+The frequency with which patients of certain Th1 diseases also experience anxiety(({{pubmed>long:8818377}})) (({{pubmed>long:18774427}})) (({{pubmed>long:18774427}})) (({{pubmed>long:9361174}})) (({{pubmed>long:15569892}})) (({{pubmed>long:7883407}})) (({{pubmed>long:9707157}})) (({{pubmed>long:12011605}})) (({{pubmed>long:11391746}})) may also suggest a single underlying cause.
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 //**John McDonald**// </blockquote>
-<blockquote>
-The first few months on Phase Two were the most difficult for me. Anything connected with emotion was difficult and when it came to physical things, I felt sluggish - as if were doing everything in a swimming pool, working against the force of water. Mental confusion and despair may be better if you rest more and keep in mind that this is //temporary// like all other Herxing. You //will// come out of this dark tunnel to see better scenery at the other end.
-//**Belinda Fenter**// </blockquote>
 <blockquote>
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 <DiseaseHierarchy>
-EDIT
   * Legacy content
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 PMID: 17920243</blockquote>
+<blockquote>Mice raised in environments without any bacteria were far more likely to take risks than mice that had a normal mix of microbes, Sven Pettersson, a cellular microbiologist at the Karolinska Institute in Stockholm and the Genome Institute of Singapore, discovered with his colleagues. Mice generally skulk around in shadows and stay close to walls, but that behavior may not be the mice’s idea alone.
+Mice raised in a sterile environment were much bolder, literally going out on a ledge more often than mice reared with bacteria in their bellies, Pettersson’s team reported in the Feb. 15 Proceedings of the National Academy of Sciences. Bacteria-free mice were also more active overall than their bacteria-laden counterparts. Inoculating bacteria-free newborn mice with intestinal bacteria reversed the changes in behavior. But restoring gut bacteria in adult bacteria-free mice did not change the rodents’ behavior, indicating that whatever bacteria do to the brain, they do it early in life.
+Bacteria’s presence or absence affected how the mice used certain brain chemicals and genes involved in brain development. Taken together, the results indicate that intestinal bacteria somehow shape the brain and make mice more anxious — or cautious, depending how you look at it, Pettersson says.
+</blockquote>
 ===== References =====

home/diseases/anxiety.txt · Last modified: 09.14.2022 by 127.0.0.1