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--- home:diseases:bipolar [12.04.2018] – [Evidence of infectious cause] sallieq
+++ home:diseases:bipolar [07.14.2019] – [Recent research] sallieq
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-<note>Dear MPKB Reader: You have arrived at one of the articles that has not yet completed the development and review process in the knowledge base. Some of the content here may be helpful, but please know that this page is not complete. There are about 400 articles in the KB, and this is one we are still working on. Thanks for your patience.</note>
+===== Recent research =====
+ It is possible that increased UA levels are a trait marker of higher vulnerability to bipolar disorder, and are even more increased during mania (mostly in the first manic episode of drug-naïve patients). (({{pubmed>long:25462413}}))
+magnetic resonance imaging confirms that hyperuricemia in rats and humans are associated with gliosis* in the hippocampus (({{pubmed>long:27798180}}))
+The hippocampal response to psychosocial stress varies with salivary uric acid level
+Uric acid may play an important role in mental health by modulating the emotional response to stress.
+The current study provides novel evidence that brain function varies with baseline uric acid level. Specifically, these results demonstrate that uric acid is associated with a greater hippocampal response to psychosocial stress. (({{pubmed>long:27725214}}))
+==== astroglia ====
+* Astrocytes perform many functions, including biochemical support of endothelial cells that form the blood–brain barrier, provision of nutrients to the nervous tissue, maintenance of extracellular ion balance, and a role in the repair and scarring process of the brain and spinal cord following traumatic injuries. Astrocytes are a type of glial cells and they hold various roles, mostly supporting neurons.
 ===== Notes and comments =====
-<DiseaseHierarchy>
+  (({{pubmed>long:000}}))
 --- //Sallie Q 08.25.2017// removed
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+<DiseaseHierarchy>
  * Legacy content

home/diseases/bipolar.txt · Last modified: 09.14.2022 by 127.0.0.1