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home:diseases:bipolar [02.11.2019]
sallieq [Notes and comments]
home:diseases:bipolar [07.14.2019] (current)
sallieq [astroglia]
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  It is possible that increased UA levels are a trait marker of higher vulnerability to bipolar disorder, and are even more increased during mania (mostly in the first manic episode of drug-naïve patients). (({{pubmed>​long:​25462413}}))  ​  It is possible that increased UA levels are a trait marker of higher vulnerability to bipolar disorder, and are even more increased during mania (mostly in the first manic episode of drug-naïve patients). (({{pubmed>​long:​25462413}}))  ​
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 +magnetic resonance imaging confirms that hyperuricemia in rats and humans are associated with gliosis* in the hippocampus (({{pubmed>​long:​27798180}}))
  
  
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 The current study provides novel evidence that brain function varies with baseline uric acid level. Specifically,​ these results demonstrate that uric acid is associated with a greater hippocampal response to psychosocial stress. (({{pubmed>​long:​27725214}}))  ​ The current study provides novel evidence that brain function varies with baseline uric acid level. Specifically,​ these results demonstrate that uric acid is associated with a greater hippocampal response to psychosocial stress. (({{pubmed>​long:​27725214}}))  ​
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 +==== astroglia ====
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 +Astrocytes perform many functions, including biochemical support of endothelial cells that form the blood–brain barrier, provision of nutrients to the nervous tissue, maintenance of extracellular ion balance, and a role in the repair and scarring process of the brain and spinal cord following traumatic injuries. ​
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 +* Astrocytes are a type of glial cells and they hold various roles, mostly supporting neurons.
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 ===== Notes and comments ===== ===== Notes and comments =====
home/diseases/bipolar.1549923700.txt.gz · Last modified: 02.11.2019 by sallieq
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