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home:diseases:cancer [12.01.2018] – [Inflammation induces cancer] sallieq | home:diseases:cancer [06.29.2019] – [Stress derived from interaction of particular personalities] sallieq | ||
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Several patients have worked with their doctors to treat their cancer with the Marshall Protocol. However, the MP appears to be most effective as a preventative measure. | Several patients have worked with their doctors to treat their cancer with the Marshall Protocol. However, the MP appears to be most effective as a preventative measure. | ||
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+ | It may be particularly important for MP patients with cancer in the family to avoid caffeine as far as possible. | ||
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+ | "It is difficult to assess the practical significance of phagocytic suppression, | ||
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=====Evidence of infectious cause===== | =====Evidence of infectious cause===== | ||
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* **liver cancer** – It is "well established" | * **liver cancer** – It is "well established" | ||
* **lung cancer** – According to a 2011 meta-analysis, | * **lung cancer** – According to a 2011 meta-analysis, | ||
- | * **prostate cancer** – In a 2005 culture-based study, Cohen found that // | + | * **prostate cancer** – In a 2005 culture-based study, Cohen found that // |
+ | * **Table of cancers** with associated agents. [[https:// | ||
With the recent advent of high throughput sequencing studies, we can expect additional insights into how diseases like cancer are associated with shifts in microbial communities. | With the recent advent of high throughput sequencing studies, we can expect additional insights into how diseases like cancer are associated with shifts in microbial communities. | ||
- | ==== see also MPSS Discussion | + | ==== see also M P Study Site ==== |
[[https:// | [[https:// | ||
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+ | ===== Innate immunity ===== | ||
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+ | < | ||
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+ | "It turns out macrophages need to be primed before they can go to work, which explains why solid tumors may resist treatment with CD47 inhibitors alone," | ||
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+ | Increasing evidence supports the occurrence of an intriguing link between tumor onset and development with the microenvironment in which cancer cells are embedded. In this context, a critical role of CD73, in calibrating the duration, magnitude and composition of adenosine signaling in cancer development and progression, | ||
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+ | The Vitamin D3 analogue calcipotriol suppresses CpG-activated TLR9-MyD88 signalling in murine plasmacytoid dendritic cells (({{pubmed> | ||
{{tag> | {{tag> | ||
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- | ==== Are There Concerns About Over-supplementing with Vitamin | + | ==== Are There Concerns About V.D Supplement |
There is a common misconception that vitamin D supplementation is safe at any reasonable level, or that if some is good, more may be better. | There is a common misconception that vitamin D supplementation is safe at any reasonable level, or that if some is good, more may be better. | ||
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+ | The Vitamin D3 analogue calcipotriol suppresses CpG-activated TLR9-MyD88 signalling in murine plasmacytoid dendritic cells (({{pubmed> | ||
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+ | Vitamin D receptor-mediated skewed differentiation of macrophages initiates myelofibrosis and subsequent osteosclerosis. (({{pubmed> | ||
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+ | 2014 a Cochrane meta-analysis that included 18 randomized clinical trials comparing vitamin D administration versus no intervention in healthy population found no difference regarding cancer incidence. | ||
====1, | ====1, | ||
Mawer //et al.// reported that 1,25-D is such a sensitive indicator of the immune response that it can even be used to determine prognosis in breast cancer with bone metastasis.(({{pubmed> | Mawer //et al.// reported that 1,25-D is such a sensitive indicator of the immune response that it can even be used to determine prognosis in breast cancer with bone metastasis.(({{pubmed> | ||
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+ | [[https:// | ||
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+ | ==== Other Immune Suppressants ==== | ||
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+ | Women with hereditary cancer predispositions should put their smartphones, | ||
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+ | Glioblastomas and malignant gliomas are the most common primary malignant brain tumors, with an annual incidence of 5.26 per 100,000 population. These tumors are typically associated with a dismal prognosis and poor quality of life. Only radiation exposure and certain genetic syndromes are well-defined risk factors for malignant glioma. | ||
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+ | This compound has antiproliferative and antimigratory effects in squamous cell carcinoma, glioblastoma, | ||
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+ | Several researchers have highlighted a possible link between glioma and human cytomegalovirus (HCMV). | ||
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+ | [[https:// | ||
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+ | [[https:// | ||
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Alicia H. Chang and Julie Parsonnet of Stanford University writes that a transmissible cause of cancer was suspected as early as the 16th century. It was not until the late 20th century definitively identified a bacterial cause of at least some types of cancer to most researchers' | Alicia H. Chang and Julie Parsonnet of Stanford University writes that a transmissible cause of cancer was suspected as early as the 16th century. It was not until the late 20th century definitively identified a bacterial cause of at least some types of cancer to most researchers' | ||
- | A number of types of chronic infection have been observed to be associated with cancers in some studies, but without an identified specific bacterial pathogen. Examples are chronic ulcers and osteomyelitis | + | A number of types of chronic infection have been observed to be associated with cancers in some studies, but without an identified specific bacterial pathogen. Examples are chronic ulcers and osteomylitis, |
The Marshall Pathogenesis is at complete odds with Koch's postulates, suggesting that it is not one species but entire communities of microbes that are responsible for many cancers. The process by which a person accumulates microbes responsible for disease is known as “successive infection.” In successive infection, an infectious cascade of pathogens progressively slow the immune response and allow for subsequent infections to proliferate, | The Marshall Pathogenesis is at complete odds with Koch's postulates, suggesting that it is not one species but entire communities of microbes that are responsible for many cancers. The process by which a person accumulates microbes responsible for disease is known as “successive infection.” In successive infection, an infectious cascade of pathogens progressively slow the immune response and allow for subsequent infections to proliferate, | ||
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< | < | ||
- | Advanced stage follicular lymphoma (FL) is incurable by conventional therapies.(({{pubmed> | + | Advanced stage follicular lymphoma (FL) is incurable by conventional therapies...... |
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{{section>: | {{section>: | ||
+ | < | ||
- | ====Tobacco==== | + | |
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+ | ==== Tobacco ==== | ||
{{section>: | {{section>: | ||
- | =====Marshall Protocol as a treatment for cancer? | + | ==== Stress derived from interaction of particular personalities ==== |
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+ | in particular [[https:// | ||
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+ | from https:// | ||
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+ | < | ||
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+ | In an extreme case, there may be someone who is literally toxic, even socio-pathic. “Learn to value yourself, Learn to say No!” and if necessary, Remove yourself from the influence of any such person.</ | ||
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+ | ===== Marshall Protocol as a treatment for cancer? ===== | ||
The MP uses olmesartan to activate the VDR, a nuclear receptor which is downregulated in cancer. While the MP appears to be a sensible preventive, it is not suitable for treating active metastasis. | The MP uses olmesartan to activate the VDR, a nuclear receptor which is downregulated in cancer. While the MP appears to be a sensible preventive, it is not suitable for treating active metastasis. | ||
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</ | </ | ||
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+ | ==== Research ==== | ||
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+ | This result provides a new idea on the anti-tumor mechanism of olmesartan, which may be used as a novel therapeutic target of cervical cancer. | ||
====Safety of olmesartan==== | ====Safety of olmesartan==== | ||
< | < | ||
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Note also that the primary ARBs being evaluated, candesartan and telmisartan, | Note also that the primary ARBs being evaluated, candesartan and telmisartan, | ||
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+ | ==== Risk ==== | ||
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+ | < | ||
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+ | CONCLUSION: | ||
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=====Other treatments===== | =====Other treatments===== | ||
- | ====Vitamin D======== | ||
- | < | ||
- | {{section> | + | [[http:// |
====Chemotherapy and radiation==== | ====Chemotherapy and radiation==== | ||
- | Chemotherapy is aggressively immunosuppressive, | + | Chemotherapy is aggressively immunosuppressive, |
+ | ==== Treatment for acute active Cancers==== | ||
+ | [[https:// | ||
+ | [[http:// | ||
+ | ==== Toll-like receptor 9 (TLR9) agonists ==== | ||
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+ | The activity and safety of these novel anticancer agents are being explored in a wide range of tumor types as part of a variety of therapeutic strategies with the goal of harnessing the immune response to fight cancer. | ||
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+ | Activation of Toll-Like Receptor 9 by DNA from Different Bacterial Species | ||
====Vaccines==== | ====Vaccines==== | ||
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//**Gene**, MarshallProtocol.com//</ | //**Gene**, MarshallProtocol.com//</ | ||
+ | ==== Vitamin D==== | ||
+ | < | ||
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+ | {{section>: | ||
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+ | === Vitamin E === | ||
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+ | Vitamin E supplementation and the risk of heart failure in women. | ||
+ | (({{pubmed> | ||
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+ | Supplementation with vitamin E did not result in any significant improvements in prognostic or functional indexes of heart failure or in the quality of life of patients with advanced heart failure.(({{pubmed> | ||
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+ | Canolol was found to counteract the fibrotic effects of vitamin E + CoQ10 on cardiac fibrosis in the context of a high-fat diet enriched with RSO. This effect occurred through a restoration of cardiac Ag2R-1b mRNA expression and decreased ischemia.(({{pubmed> | ||
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// | // | ||
</ | </ | ||
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</ | </ | ||
- | < | + | < |
+ | I found breast cancer in 1990, had a lumpectomy and follow up mastectomy with lymph node removal, as the cancer had begun to spread there. Similarly spreading, but in different organs, killed my mother at a slightly later stage of life. She had not sought treatment until too late. I have no doubt that prompt surgery and follow up radiotherapy and tamoxifen saved my life. At that period there were no alternatives or understanding of the microbiome. | ||
Interestingly, | Interestingly, | ||
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</ | </ | ||
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+ | ===== Recent research ===== | ||
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+ | Paclitaxel Reduces Tumor Growth by Reprogramming Tumor-Associated Macrophages to an M1 Profile in a TLR4-Dependent Manner. | ||
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+ | {{section>: | ||
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+ | Discovery of novel nonsteroidal VDR agonists with novel diarylmethane skeleton for the treatment of breast cancer. (({{pubmed> | ||
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+ | Olmesartan and Bay11-7082 inhibit the MCF-7 cells growth indicating RAS and NF-kappaB pathway blockade lead to cytotoxicity and apoptosis induction against tumour cells. So ARBs and NF-kappaB pathway inhibitors could be considered as anticancer drugs in future. | ||
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+ | In this large population-based gastro-oesophageal cancer cohort, we found moderately reduced cancer-specific mortality among ARB users. However, confirmation in further independent epidemiological studies with sufficient staging information is required. | ||
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+ | miR-205 mediates the inhibition of cervical cancer cell proliferation using olmesartan. | ||
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+ | Therapeutic potentials of SCFA receptors [section 7 in | ||
+ | Recent progress in understanding the role of GPR41, GPR43 and GPR109A in health and disease demonstrate that these receptors do not just regulate inflammation and cancer in intestine, but also influence other gastrointestinal functions, allergies, adipogenesis, | ||
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+ | Using metabolomics, | ||
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+ | Vitamin D and immune cells stimulate bone marrow disease (({{pubmed> | ||
=====Read more===== | =====Read more===== | ||
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* [[https:// | * [[https:// | ||
* [[https:// | * [[https:// | ||
- | * [[http:// | + | * [[http:// |
* [[http:// | * [[http:// | ||
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+ | (({{pubmed> | ||
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+ | (({{pubmed> | ||
New Evidence Links Virus to Brain Cancer - http:// | New Evidence Links Virus to Brain Cancer - http:// | ||