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home:diseases:cancer [03.13.2019] – [Recent research] sallieq | home:diseases:cancer [03.21.2019] – [Recent research] sallieq | ||
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This result provides a new idea on the anti-tumor mechanism of olmesartan, which may be used as a novel therapeutic target of cervical cancer. | This result provides a new idea on the anti-tumor mechanism of olmesartan, which may be used as a novel therapeutic target of cervical cancer. | ||
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Note also that the primary ARBs being evaluated, candesartan and telmisartan, | Note also that the primary ARBs being evaluated, candesartan and telmisartan, | ||
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< | < | ||
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Olmesartan and Bay11-7082 inhibit the MCF-7 cells growth indicating RAS and NF-kappaB pathway blockade lead to cytotoxicity and apoptosis induction against tumour cells. So ARBs and NF-kappaB pathway inhibitors could be considered as anticancer drugs in future. | Olmesartan and Bay11-7082 inhibit the MCF-7 cells growth indicating RAS and NF-kappaB pathway blockade lead to cytotoxicity and apoptosis induction against tumour cells. So ARBs and NF-kappaB pathway inhibitors could be considered as anticancer drugs in future. | ||
+ | In this large population-based gastro-oesophageal cancer cohort, we found moderately reduced cancer-specific mortality among ARB users. However, confirmation in further independent epidemiological studies with sufficient staging information is required. | ||
+ | miR-205 mediates the inhibition of cervical cancer cell proliferation using olmesartan. | ||
- | In this large population-based gastro-oesophageal cancer cohort, we found moderately reduced cancer-specific mortality among ARB users. However, confirmation in further independent epidemiological studies with sufficient staging information is required. | ||
Vitamin D and immune cells stimulate bone marrow disease (({{pubmed> | Vitamin D and immune cells stimulate bone marrow disease (({{pubmed> |