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home:diseases:cancer [05.16.2019] – [Recent research] sallieq | home:diseases:cancer [06.12.2019] – [Recent research] sallieq | ||
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- | Women with hereditary | + | Women with hereditary cancer predispositions should |
Glioblastomas and malignant gliomas are the most common primary malignant brain tumors, with an annual incidence of 5.26 per 100,000 population. These tumors are typically associated with a dismal prognosis and poor quality of life. Only radiation exposure and certain genetic syndromes are well-defined risk factors for malignant glioma. | Glioblastomas and malignant gliomas are the most common primary malignant brain tumors, with an annual incidence of 5.26 per 100,000 population. These tumors are typically associated with a dismal prognosis and poor quality of life. Only radiation exposure and certain genetic syndromes are well-defined risk factors for malignant glioma. | ||
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+ | This compound has antiproliferative and antimigratory effects in squamous cell carcinoma, glioblastoma, | ||
Several researchers have highlighted a possible link between glioma and human cytomegalovirus (HCMV). | Several researchers have highlighted a possible link between glioma and human cytomegalovirus (HCMV). | ||
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===== Recent research ===== | ===== Recent research ===== | ||
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Paclitaxel Reduces Tumor Growth by Reprogramming Tumor-Associated Macrophages to an M1 Profile in a TLR4-Dependent Manner. | Paclitaxel Reduces Tumor Growth by Reprogramming Tumor-Associated Macrophages to an M1 Profile in a TLR4-Dependent Manner. | ||
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{{section>: | {{section>: | ||
Discovery of novel nonsteroidal VDR agonists with novel diarylmethane skeleton for the treatment of breast cancer. (({{pubmed> | Discovery of novel nonsteroidal VDR agonists with novel diarylmethane skeleton for the treatment of breast cancer. (({{pubmed> | ||
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- | This compound has antiproliferative and antimigratory effects in squamous cell carcinoma, glioblastoma, | ||
Olmesartan and Bay11-7082 inhibit the MCF-7 cells growth indicating RAS and NF-kappaB pathway blockade lead to cytotoxicity and apoptosis induction against tumour cells. So ARBs and NF-kappaB pathway inhibitors could be considered as anticancer drugs in future. | Olmesartan and Bay11-7082 inhibit the MCF-7 cells growth indicating RAS and NF-kappaB pathway blockade lead to cytotoxicity and apoptosis induction against tumour cells. So ARBs and NF-kappaB pathway inhibitors could be considered as anticancer drugs in future. | ||
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In this large population-based gastro-oesophageal cancer cohort, we found moderately reduced cancer-specific mortality among ARB users. However, confirmation in further independent epidemiological studies with sufficient staging information is required. | In this large population-based gastro-oesophageal cancer cohort, we found moderately reduced cancer-specific mortality among ARB users. However, confirmation in further independent epidemiological studies with sufficient staging information is required. | ||
- | miR-205 mediates the inhibition of cervical cancer cell proliferation using olmesartan. | + | miR-205 mediates the inhibition of cervical cancer cell proliferation using olmesartan. |
Therapeutic potentials of SCFA receptors [section 7 in | Therapeutic potentials of SCFA receptors [section 7 in | ||
Recent progress in understanding the role of GPR41, GPR43 and GPR109A in health and disease demonstrate that these receptors do not just regulate inflammation and cancer in intestine, but also influence other gastrointestinal functions, allergies, adipogenesis, | Recent progress in understanding the role of GPR41, GPR43 and GPR109A in health and disease demonstrate that these receptors do not just regulate inflammation and cancer in intestine, but also influence other gastrointestinal functions, allergies, adipogenesis, | ||
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+ | Using metabolomics, | ||