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--- home:diseases:cardiovascular [10.19.2018] – [Notes and comments] sallieq
+++ home:diseases:cardiovascular [12.26.2018] – [Effect of olmesartan on cardiovascular diseases] + ref. & Jigsaw quote sallieq
@@ Line 122: / Line 122: @@
 //**R. Han**// (({{pubmed>long:20377753}}))</blockquote>
+<blockquote>much confusion has arisen from unclear nomenclature with regard to polyunsaturated fatty acids and the lack of reporting of food sources in prospective cohorts. Data from prospective cohort studies and randomized controlled trials generally support the replacement of saturated fats with mixed polyunsaturated fatty acids to reduce the risk of death from coronary artery disease. However, it is unclear whether oils rich in omega-6 linoleic acid but low in omega-3 α-linolenic acid also reduce this risk.
+//Richard P. Bazinet, PhD and Michael W.A. Chu, MD MEd//  (({{pubmed>long:24218530}}))
+Key points
+  * The replacement of dietary saturated fats with some, but not all polyunsaturated fatty acids reduces serum cholesterol levels and the risk of heart disease.
+  * New analyses suggest that replacing saturated animal fats with linoleic acid, an omega-6 polyunsaturated fatty acid, lowers serum cholesterol levels but increases the risk of death from coronary artery disease.
+  * Health Canada’s Food Directorate should reconsider the health claim that omega-6 polyunsaturated fatty acids reduce the risk of heart disease by lowering blood cholesterol levels.
+//Richard P. Bazinet, PhD and Michael W.A. Chu, MD MEd//</blockquote>
 ==== Homocysteine====
@@ Line 135: / Line 145: @@
 Marino //et al.// showed that eradication of //Helicobacter pylori// associated with gastritis reduced abnormally high levels of homocysteine.(({{pubmed>long:17005765}}))
+The role of hyperhomocysteinemia in coronary artery disease (CAD) patients remains unclear.  (({{pubmed>long:26762617}}))
@@ Line 149: / Line 161: @@
 {{section>:home:protocol:olmesartan#cardiovascular_disease&noheader}}
+ <blockquote>//Jigsaw wrote// Since Elizabeth Blackburn won a Nobel prize for telomerase in 2009, I have wondered what effect olmesartan might have on it. //Are our telomeres getting shorter and shorter, so we just go POP?//  while getting healthier and healthier in other respects.     This report (({{pubmed>long:27079876}})) is re-assuring. Olmesartan raises ACE2 which converts angII to Ang 1-7</blockquote>
 ===== Other treatments =====

home/diseases/cardiovascular.txt · Last modified: 09.14.2022 by 127.0.0.1