This shows you the differences between two versions of the page.
Both sides previous revisionPrevious revisionNext revision | Previous revision | ||
home:diseases:celiac [02.15.2019] – [recent research] sallieq | home:diseases:celiac [09.14.2022] (current) – external edit 127.0.0.1 | ||
---|---|---|---|
Line 5: | Line 5: | ||
====== Celiac disease ====== | ====== Celiac disease ====== | ||
+ | < | ||
- | People with celiac disease react to gluten, which is found in wheat, rye, spelt and barley. Villus atrophy in the small intestine is one of the most significant findings in celiac disease, rendering the patient with a poor absorptive capacity. | + | |
+ | People with celiac disease react to gluten, which is found in wheat, rye, spelt and barley. Villus atrophy in the small intestine is one of the most significant findings in celiac disease, rendering the patient with a poor absorptive capacity. | ||
===== Epidemiology ===== | ===== Epidemiology ===== | ||
+ | After birth, an infant' | ||
+ | “Differences in the microbial flora and impaired priming of the enteric epithelial surface in individuals who are born by cesarean delivery might therefore contribute to inflammatory conditions of the intestinal mucosa later in life,” write lead author Evalotte Decker, from the Department of Pediatrics, Institute for Medical Microbiology and Hospital Epidemiology, | ||
- | < | + | < |
Cesarean delivery is associated with celiac disease but not inflammatory bowel disease in children. | Cesarean delivery is associated with celiac disease but not inflammatory bowel disease in children. | ||
- | Decker E, Engelmann G, Findeisen A, Gerner P, Laass M, Ney D, Posovszky C, Hoy L, Hornef MW. | + | |
- | Department of Pediatrics, Institute for Medical Microbiology and Hospital Epidemiology, | + | |
- | Comment in: | + | |
- | Nat Rev Gastroenterol Hepatol. 2010 Aug; | + | |
Abstract | Abstract | ||
OBJECTIVES: The aim of this study was to analyze a possible association between cesarean delivery and enteric inflammatory diseases in children. | OBJECTIVES: The aim of this study was to analyze a possible association between cesarean delivery and enteric inflammatory diseases in children. | ||
- | METHODS: A retrospective, | ||
- | RESULTS: Whereas the rate of cesarean delivery of children with Crohn disease or ulcerative colitis was similar to that of control subjects, a significantly enhanced likelihood of being born by cesarean delivery was found in children with celiac disease compared with control subjects (odds ratio: 1.8 [95% confidence interval: 1.13-2.88]; P = .014). | ||
- | CONCLUSIONS: | ||
- | </ | ||
- | Infants Delivered By Cesarean May Be More Likely to Develop Celiac Disease | + | METHODS: A retrospective, |
- | Nancy Fowler Larson | + | |
- | May 19, 2010 — Cesarean | + | RESULTS: Whereas the rate of cesarean |
- | After birth, an infant' | ||
- | " | + | CONCLUSIONS: |
+ | </ | ||
+ | |||
+ | The emerging data on viral and bacterial microbe-host interactions | ||
- | The investigators conducted a retrospective, | ||
===== Celiac and D metabolite levels ===== | ===== Celiac and D metabolite levels ===== | ||
- | Some patients with celiac disease have low/normal 25D but elevated 1,25D apparently related to celiac. | + | Some patients with celiac disease have low/normal 25D but elevated 1,25D apparently related to celiac. |
- | Our patient had hypocalcemia caused by celiac disease and values for serum 25-hydroxyvitamin D and 1, | + | Our patient had hypocalcemia caused by celiac disease and values for serum 25-hydroxyvitamin D and 1, |
- | Calcium and vitamin D supplement intake may increase arterial stiffness in systemic lupus erythematosus patients. (({{pubmed> | + | Calcium and vitamin D supplement intake may increase arterial stiffness in systemic lupus erythematosus patients. (({{pmid> |
- | (({{pubmed> | + | (({{pmid> |
===== Evidence of infectious cause ===== | ===== Evidence of infectious cause ===== | ||
- | < | + | < |
</ | </ | ||
< | < | ||
- | Sabayan B, Foroughinia F, Imanieh MH (({{pubmed> | + | Sabayan B, Foroughinia F, Imanieh MH (({{pmid> |
- | Specific duodenal and faecal bacterial groups are associated with paediatric celiac disease.(({{pubmed> | + | Specific duodenal and faecal bacterial groups are associated with paediatric celiac disease.(({{pmid> |
- | Lymphocytic gastritis and celiac disease in indian children: evidence of a positive relation.(({{pubmed> | + | Lymphocytic gastritis and celiac disease in indian children: evidence of a positive relation.(({{pmid> |
- | Autoantibodies involved in celiac disease are not specific, as infection may increase levels of anti-transglutaminase antibodies. These antibodies are not detectable once the infection is gone.(({{pubmed> | + | Autoantibodies involved in celiac disease are not specific, as infection may increase levels of anti-transglutaminase antibodies. These antibodies are not detectable once the infection is gone.(({{pmid> |
==== recent research ==== | ==== recent research ==== | ||
Line 65: | Line 63: | ||
Could a common virus trigger coeliac disease in some children? | Could a common virus trigger coeliac disease in some children? | ||
- | [[http:// | + | [[https:// |
- | (({{pubmed> | + | (({{pmid> |
- | {{tag>diseases}} | + | Findings suggest that neither olmesartan nor other ARBs were associated with diarrhea among patients undergoing endoscopy. The spruelike enteropathy recently associated with olmesartan is likely a rare adverse effect and milder presentations are unlikely. |
+ | In 2015 I saw that 6 individuals in the USA were suing maker of Benicar. (// | ||
+ | Gluten in " | ||
+ | 2018 data show that OLM is an Nrf2 activator, NFkB inhibitor and apoptosis inhibitor in an experimental model of ulcerative colitis. Overall, the study indicates that OLM shows promise as a potential therapy for the treatment of human inflammatory bowel diseases. | ||
+ | (({{pmid> | ||
+ | |||
+ | Research associated with J Tye-Din | ||
+ | |||
+ | |||
+ | |||
+ | {{tag> | ||
+ | |||
+ | |||
+ | |||
+ | |||
+ | < | ||
===== Notes and comments ===== | ===== Notes and comments ===== | ||
Line 115: | Line 128: | ||
Romain Bouziat1, | Romain Bouziat1, | ||
as link will likely break (news media) | as link will likely break (news media) | ||
- | ===== References ===== | + | ===== References =====</ |