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home:diseases:cfs [07.06.2019] – [Research] sallieq | home:diseases:cfs [01.19.2020] – [Research] sallieq | ||
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====== Chronic fatigue syndrome (myalgic encephalomyelitis) ====== | ====== Chronic fatigue syndrome (myalgic encephalomyelitis) ====== | ||
- | <relatedarticle> [[home: | + | <relatedarticles> [[home: |
===== Introduction ===== | ===== Introduction ===== | ||
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This work contributes key elements to the development of ME/CFS diagnostics, | This work contributes key elements to the development of ME/CFS diagnostics, | ||
- | Disturbances in fatty acid and lipid metabolism | + | Disturbances in fatty acid and lipid metabolism |
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+ | Selenium and iodine are essential for thyroid hormone synthesis and function. (({{pubmed> | ||
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Altered composition of the gut microbiome | Altered composition of the gut microbiome | ||
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Patients with CFS showed abnormalities in 20 metabolic pathways. (({{pubmed> | Patients with CFS showed abnormalities in 20 metabolic pathways. (({{pubmed> | ||
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=====Symptoms===== | =====Symptoms===== | ||
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In October 2009, we reported the first direct isolation of infectious xenotropic murine leukemia virus-related virus (XMRV). In that study, we used a combination of biological amplification and molecular enhancement techniques to detect XMRV in more than 75% of 101 patients with chronic fatigue syndrome (CFS).(({{pubmed> | In October 2009, we reported the first direct isolation of infectious xenotropic murine leukemia virus-related virus (XMRV). In that study, we used a combination of biological amplification and molecular enhancement techniques to detect XMRV in more than 75% of 101 patients with chronic fatigue syndrome (CFS).(({{pubmed> | ||
+ | [[http:// | ||
===== Impairment of immune function ===== | ===== Impairment of immune function ===== |