Home

Differences

This shows you the differences between two versions of the page.

Link to this comparison view

Both sides previous revision Previous revision
Next revision
Previous revision
Last revision Both sides next revision
home:diseases:graves [01.01.2019]
sallieq [Evidence of infectious cause]
home:diseases:graves [01.04.2019]
sallieq [Testing]
Line 13: Line 13:
 ==== Thyroid markers ==== ==== Thyroid markers ====
  
- 
-Nanba, T., M. Watanabe, et al. (2009). "​Increases of the Th1/Th2 cell ratio in severe Hashimoto'​s disease and in the proportion of Th17 cells in intractable Graves'​ disease."​ Thyroid 19(5): 495-501. (({{pubmed>​long:​19415997}})) 
  
 BACKGROUND: T helper type 1 (Th1), Th2, and Th17 cells produce interferon (IFN)-gamma,​ interleukin (IL)-4, and IL-17A, respectively. We reported that IFN-gamma and IL-4 gene polymorphisms,​ which are related to higher IFN-gamma and lower IL-4 production, respectively,​ are more frequent in patients with severe Hashimoto'​s disease (HD) than in those mild HD. We now aim to investigate the proportion of peripheral Th1, Th2, and Th17 cells in patients with autoimmune thyroid disease (AITD). ​ BACKGROUND: T helper type 1 (Th1), Th2, and Th17 cells produce interferon (IFN)-gamma,​ interleukin (IL)-4, and IL-17A, respectively. We reported that IFN-gamma and IL-4 gene polymorphisms,​ which are related to higher IFN-gamma and lower IL-4 production, respectively,​ are more frequent in patients with severe Hashimoto'​s disease (HD) than in those mild HD. We now aim to investigate the proportion of peripheral Th1, Th2, and Th17 cells in patients with autoimmune thyroid disease (AITD). ​
Line 23: Line 21:
  
 CONCLUSIONS:​ The peripheral Th1/Th2 cell ratio is related to the severity of HD, and the proportion of Th17 cells is related to the intractability of GD. We hypothesize that these patterns of peripheral Th cell subsets may be expressed within the thyroid. CONCLUSIONS:​ The peripheral Th1/Th2 cell ratio is related to the severity of HD, and the proportion of Th17 cells is related to the intractability of GD. We hypothesize that these patterns of peripheral Th cell subsets may be expressed within the thyroid.
 +
 +
 +//Nanba, T., M. Watanabe, et al. (2009).// "​Increases of the Th1/Th2 cell ratio in severe Hashimoto'​s disease and in the proportion of Th17 cells in intractable Graves'​ disease."​ . (({{pubmed>​long:​19415997}}))
 ===== Evidence of infectious cause ===== ===== Evidence of infectious cause =====
  
Line 52: Line 53:
 //​Hogan//</​blockquote>​ //​Hogan//</​blockquote>​
  
-{{tag>​diseases ​arrange}}+{{tag>​diseases }}
  
  
home/diseases/graves.txt · Last modified: 01.18.2020 by sallieq
© 2015, Autoimmunity Research Foundation. All Rights Reserved.