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--- home:diseases:hlh [01.03.2012] – external edit 127.0.0.1
+++ home:diseases:hlh [09.14.2022] (current) – external edit 127.0.0.1
@@ Line 10: / Line 10: @@
 Several findings link the syndrome to infections:
-  * The immune system is activated. High levels of serum TNF-α, interleukins, IFN-γ have been found in HLH patients.(({{pubmed>long:11076718}})) The actual hemophagocytosis is undertaken by macrophages.
+  * The immune system is activated. High levels of serum TNF-α, interleukins, IFN-γ have been found in HLH patients.(({{pmid>long:11076718}})) The actual hemophagocytosis is undertaken by macrophages.
-  * HLH has been associated with the following microbes: Epstein-Barr virus,(({{pubmed>long:20504238}})) //Salmonella thyphi//,(({{pubmed>long:10910545}})) Herpes simplex virus 1,(({{pubmed>long:20504238}})) HHV-6,(({{pubmed>long:20400100}})) //Mycobacterium tuberculosis//(({{pubmed>long:19449255}})) and other infectious agents.(({{pubmed>long:11076718}}))
+  * HLH has been associated with the following microbes: Epstein-Barr virus,(({{pmid>long:20504238}})) //Salmonella thyphi//,(({{pmid>long:10910545}})) Herpes simplex virus 1,(({{pmid>long:20504238}})) HHV-6,(({{pmid>long:20400100}})) //Mycobacterium tuberculosis//(({{pmid>long:19449255}})) and other infectious agents.(({{pmid>long:11076718}}))
-  * Treatment of infections can reduce hemophagocytosis.(({{pubmed>long:20504238}}))
+  * Treatment of infections can reduce hemophagocytosis.(({{pmid>long:20504238}}))
 ==== Possible mechanism for hemophagocytosis ====
-The actual hemophagocytosis may be viewed as a result of overstimulated macrophages. While blood cells may harbour infectious agents and therefore the infected individual could benefit from the macrophages attacking the blood cells, there is also the possibility that hemophagocytosis benefits the infectious agent. Bacteria in hemophagocytic macrophages could access nutrients from the ingested cells, or hemophagocytic macrophages could reduce bacteria-killing activity by killing the very cells that could attack them.  Yet, other macrophages could still be sufficiently activated to generate additional hemophagocytic macrophages.(({{pubmed>long:18085823}}))
+The actual hemophagocytosis may be viewed as a result of overstimulated macrophages. While blood cells may harbour infectious agents and therefore the infected individual could benefit from the macrophages attacking the blood cells, there is also the possibility that hemophagocytosis benefits the infectious agent. Bacteria in hemophagocytic macrophages could access nutrients from the ingested cells, or hemophagocytic macrophages could reduce bacteria-killing activity by killing the very cells that could attack them.  Yet, other macrophages could still be sufficiently activated to generate additional hemophagocytic macrophages.(({{pmid>long:18085823}}))
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-{{tag>Diseases}}
+{{tag>Disease}}
+<nodisp>
 ===== Notes and comments =====
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 So far, so good, Inge. Note the syntax for references.  --- //Paul Albert 07.15.2010//
-===== References =====
+===== References =====</nodisp>

home/diseases/hlh.txt · Last modified: 09.14.2022 by 127.0.0.1