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home:diseases:osteoporosis_osteopenia [12.19.2018] – [Vitamin D supplementation] sallieq | home:diseases:osteoporosis_osteopenia [01.14.2020] – [Evidence of infectious cause] sallieq | ||
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====== Osteoporosis and osteopenia ====== | ====== Osteoporosis and osteopenia ====== | ||
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Both osteoporosis and osteopenia are diseases marked by a decrease in bone mineral density. Osteopenia is a less severe form of and sometimes precursor to osteoporosis. The loss of bone mass leads to a porous bone structure, frequent fractures, and delayed healing. | Both osteoporosis and osteopenia are diseases marked by a decrease in bone mineral density. Osteopenia is a less severe form of and sometimes precursor to osteoporosis. The loss of bone mass leads to a porous bone structure, frequent fractures, and delayed healing. | ||
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===== Other treatments ===== | ===== Other treatments ===== | ||
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+ | Calcitonin | ||
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+ | Through these processes, bone matrix resorption and serum calcium are both decreased. | ||
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+ | ==== Cannabinoids | ||
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+ | An optimal correlation of cannabinoid dose, duration, moment of action, and affinity can lead to an increased bone regeneration capacity | ||
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+ | Heavy cannabis use is associated with low bone mineral density, low BMI, high bone turnover, and an increased risk of fracture. (({{pubmed> | ||
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+ | [[https:// | ||
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+ | Cannabinoids induce incomplete maturation of cultured human leukemia cells. (({{pubmed> | ||
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+ | The psychoactive component of marijuana, delta9-tetrahydrocannabinol (THC) suppresses different functions of immunocytes, | ||
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+ | the first observations of GcMAF effects on the transcriptionomics of the endocannabinoid system and expression of CB2R protein. These data point to a potential nexus between endocannabinoids, | ||
==== Calcium supplementation ==== | ==== Calcium supplementation ==== | ||
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==== Vitamin D supplementation ==== | ==== Vitamin D supplementation ==== | ||
- | Some clinicians encourage patients with inadequate bone density to supplement with vitamin D and calcium. While [[home: | + | Some clinicians encourage patients with inadequate bone density to supplement with vitamin D and calcium. |
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=== Interventional trials showing vitamin D is ineffective | === Interventional trials showing vitamin D is ineffective | ||
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* **certain antibiotics help strengthen bones** – NIH animal studies have shown that minocycline, | * **certain antibiotics help strengthen bones** – NIH animal studies have shown that minocycline, | ||
- | * **connection with disparate diseases** – the NIH connects several Th1 diseases with higher risk of osteoporosis, | + | * **connection with disparate diseases** – the NIH connects several Th1 diseases with higher risk of osteoporosis, |