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home:diseases:parkinsons [01.10.2019] – [Neuropathology] sallieq | home:diseases:parkinsons [09.14.2022] (current) – external edit 127.0.0.1 | ||
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====== Parkinson' | ====== Parkinson' | ||
- | [[http:// | + | [[https:// |
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RESULTS: The probabilities of random occurrence (P values) in the 3 clusters were P = 7.9 x 10 (-7)for cluster 1, P = 2.6 x 10 (-7)for cluster 2, and P = 1.5 x 10 (-7)for cluster 3. | RESULTS: The probabilities of random occurrence (P values) in the 3 clusters were P = 7.9 x 10 (-7)for cluster 1, P = 2.6 x 10 (-7)for cluster 2, and P = 1.5 x 10 (-7)for cluster 3. | ||
- | CONCLUSIONS: | + | CONCLUSIONS: |
===== Gastrointestinal inflammation ===== | ===== Gastrointestinal inflammation ===== | ||
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< | < | ||
- | Colonoscopy or flexible sigmoidoscopy may be used to predict Parkinson' | + | Colonoscopy or flexible sigmoidoscopy may be used to predict Parkinson' |
</ | </ | ||
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- | CONCLUSIONS: | + | CONCLUSIONS: |
< | < | ||
- | We propose an alternative third hypothesis, in which both cigarette and coffee consumption change the composition of the microbiota in the gut in a way that mitigates intestinal inflammation. | + | We propose an alternative third hypothesis, in which both cigarette and coffee consumption change the composition of the microbiota in the gut in a way that mitigates intestinal inflammation. |
===== Neuropathology ===== | ===== Neuropathology ===== | ||
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< | < | ||
Role of chronic infection and inflammation in the gastrointestinal tract in the etiology and pathogenesis of idiopathic parkinsonism. Part 2: response of facets of clinical idiopathic parkinsonism to Helicobacter pylori eradication. A randomized, double-blind, | Role of chronic infection and inflammation in the gastrointestinal tract in the etiology and pathogenesis of idiopathic parkinsonism. Part 2: response of facets of clinical idiopathic parkinsonism to Helicobacter pylori eradication. A randomized, double-blind, | ||
- | Bjarnason IT, Charlett A, Dobbs RJ, Dobbs SM, Ibrahim MA, Kerwin RW, Mahler RF, Oxlade NL, Peterson DW, Plant JM, Price AB, Weller C. (({{pubmed> | + | Bjarnason IT, Charlett A, Dobbs RJ, Dobbs SM, Ibrahim MA, Kerwin RW, Mahler RF, Oxlade NL, Peterson DW, Plant JM, Price AB, Weller C. (({{pmid> |
Section of Neuropharmacology, | Section of Neuropharmacology, | ||
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< | < | ||
- | http:// | + | https:// |
NEW ORLEANS, LA – May 22, 2011 -- The stomach bacteria responsible for ulcers could also play a role in the development of Parkinson' | NEW ORLEANS, LA – May 22, 2011 -- The stomach bacteria responsible for ulcers could also play a role in the development of Parkinson' | ||
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Studies in the Role of chronic infection and inflammation in the gastrointestinal tract in the etiology and pathogenesis of idiopathic parkinsonism. | Studies in the Role of chronic infection and inflammation in the gastrointestinal tract in the etiology and pathogenesis of idiopathic parkinsonism. | ||
- | AIM: To consider the candidature of Helicobacter in parkinsonism with cachexia. (({{pubmed> | + | AIM: To consider the candidature of Helicobacter in parkinsonism with cachexia. (({{pmid> |
- | AIM: Proof-of-principle that infection contributes to idiopathic parkinsonism. (({{pubmed> | + | AIM: Proof-of-principle that infection contributes to idiopathic parkinsonism. (({{pmid> |
- | AIM: To explore the cross-sectional fit of parkinsonism as an extra-alimentary consequence of Helicobacter pylori, using the serum antibody profile. (({{pubmed> | + | AIM: To explore the cross-sectional fit of parkinsonism as an extra-alimentary consequence of Helicobacter pylori, using the serum antibody profile. (({{pmid> |
- | Abstract: We challenge the concept of idiopathic parkinsonism (IP) as inevitably progressive neurodegeneration (({{pubmed> | + | Abstract: We challenge the concept of idiopathic parkinsonism (IP) as inevitably progressive neurodegeneration (({{pmid> |
< | < | ||
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Abstract | Abstract | ||
- | Antibiotic therapy to eradicate Helicobacter pylori, the causative agent of gastric and duodenal ulcers, has been suggested to improve L-DOPA bioavailability in Parkinson' | + | Antibiotic therapy to eradicate Helicobacter pylori, the causative agent of gastric and duodenal ulcers, has been suggested to improve L-DOPA bioavailability in Parkinson' |
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- | I know one other person on the MP who thinks he has Parkinson' | + | I know one other person on the MP who thinks he has Parkinson' |
// | // | ||
- | ===== Recent research | + | ===== Research |
- | < | + | < |
- | [[http:// | + | < |
+ | |||
+ | The implication of tyrosine hydroxylase (TH), the enzyme that catalyzes the formation of L-3, | ||
+ | |||
+ | [[https:// | ||
{{tag> | {{tag> | ||
+ | < | ||
===== Notes and comments ===== | ===== Notes and comments ===== | ||
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- | ===== References ===== | + | ===== References =====</ |