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home:diseases:reactive_arthritis [02.17.2019] – [Diary of a patient 2005-2012, with follow up posts] sallieqhome:diseases:reactive_arthritis [09.14.2022] (current) – external edit 127.0.0.1
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-[[http://www.mayoclinic.org/diseases-conditions/reactive-arthritis/basics/definition/con-20020872|Mayo Clinic overview]]+[[https://www.mayoclinic.org/diseases-conditions/reactive-arthritis/basics/definition/con-20020872|Mayo Clinic overview]]
  
 ===== Evidence of infectious cause ===== ===== Evidence of infectious cause =====
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 <blockquote> <blockquote>
-Reactive arthritis (ReA), an inflammatory arthritic condition that is commonly associated with Chlamydia infections, represents a significant health burden, yet is poorly understood. The enigma of this disease is reflected in its problematic name and in its ill-defined pathogenesis. The existence of persistent pathogens in the arthritic joint is acknowledged, but their relevance remains elusive. Progress is being made in understanding the underlying mechanisms of ReA, whereby an imbalance between type 1 and type 2 immune responses seems to be critical in determining susceptibility to disease. Such an imbalance occurs prior to the initiation of an adaptive immune response, suggesting that innate cellular and molecular mechanisms in ReA should be prioritized as fruitful areas for investigation. (({{pubmed>long:22105240}}))+Reactive arthritis (ReA), an inflammatory arthritic condition that is commonly associated with Chlamydia infections, represents a significant health burden, yet is poorly understood. The enigma of this disease is reflected in its problematic name and in its ill-defined pathogenesis. The existence of persistent pathogens in the arthritic joint is acknowledged, but their relevance remains elusive. Progress is being made in understanding the underlying mechanisms of ReA, whereby an imbalance between type 1 and type 2 immune responses seems to be critical in determining susceptibility to disease. Such an imbalance occurs prior to the initiation of an adaptive immune response, suggesting that innate cellular and molecular mechanisms in ReA should be prioritized as fruitful areas for investigation. (({{pmid>long:22105240}}))
 </blockquote> </blockquote>
  
  
-Combination antibiotics for Chlamydia-induced arthritis: breakthrough to a cure?  (({{pubmed>long:20155826}}))+Combination antibiotics for Chlamydia-induced arthritis: breakthrough to a cure?  (({{pmid>long:20155826}}))
  
 Editorial Editorial
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-"Combination antibiotics as a treatment for chronic Chlamydia-induced reactive arthritis."   (({{pubmed>long:20155838}}))+"Combination antibiotics as a treatment for chronic Chlamydia-induced reactive arthritis."   (({{pmid>long:20155838}}))
  
 BACKGROUND:: Chlamydia trachomatis (Ct) and Chlamydophila (Chlamydia) pneumoniae (Cpn) are known triggers of reactive arthritis (ReA). These chlamydial species exist in a persistent metabolically active infection state in the synovium suggesting that persistent chlamydiae may be susceptible to antimicrobial agents. The goal of this study was to investigate whether a six-month course of combination antibiotics is an effective therapy for patients with chronic Chlamydia-induced ReA.  BACKGROUND:: Chlamydia trachomatis (Ct) and Chlamydophila (Chlamydia) pneumoniae (Cpn) are known triggers of reactive arthritis (ReA). These chlamydial species exist in a persistent metabolically active infection state in the synovium suggesting that persistent chlamydiae may be susceptible to antimicrobial agents. The goal of this study was to investigate whether a six-month course of combination antibiotics is an effective therapy for patients with chronic Chlamydia-induced ReA. 
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 +<nodisp>
 ===== Notes and comments ===== ===== Notes and comments =====
  
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 {{:home:diseases:screen_shot_2010-10-27_at_5.20.03_pm.png|}} {{:home:diseases:screen_shot_2010-10-27_at_5.20.03_pm.png|}}
  
-===== References =====+===== References =====</nodisp> 
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