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home:diseases:rheumatoid_arthritis [07.10.2019] – [Gout] sallieqhome:diseases:rheumatoid_arthritis [07.10.2019] – [Gout] sallieq
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 //David//</blockquote> //David//</blockquote>
  
-Herein, we report a positive relationship between serum UA and acute-phase reactants, such as high-sensitivity C-reactive protein, fibrinogen, ferritin, complement C3, and erythrocyte sedimentation rate, in a cohort of 2731 nondiabetic adults. The relationship remains significant after adjustment for several confounders, including age, sex, adiposity, anti-hypertensive treatments or diuretics use. To confirm the existence of a causal relationship, we examined the effect of UA on the expression of inflammatory biomarkers in human hepatoma HepG2 cells and characterized the signaling pathway by which UA acts. +Herein, we report a positive relationship between serum UA and acute-phase reactants, such as high-sensitivity C-reactive protein, fibrinogen, ferritin, complement C3, and erythrocyte sedimentation rate, in a cohort of 2731 nondiabetic adults. The relationship remains significant after adjustment for several confounders, including age, sex, adiposity, anti-hypertensive treatments or diuretics use. To confirm the existence of a causal relationship, we examined the effect of UA on the expression of inflammatory biomarkers in human hepatoma HepG2 cells and characterized the signaling pathway by which UA acts.  .......The effect of UA was completely blocked by the antioxidant N-acetylcysteine.  (({{pubmed>long:28408375}}))
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-The effect of UA was completely blocked by the antioxidant N-acetylcysteine. +
-(({{pubmed>long:28408375}}))+
  
  
home/diseases/rheumatoid_arthritis.txt · Last modified: 09.14.2022 by 127.0.0.1
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