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home:diseases:rheumatoid_arthritis [07.10.2019] – [Gout] sallieq | home:diseases:rheumatoid_arthritis [09.14.2022] (current) – external edit 127.0.0.1 | ||
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=====Management ===== | =====Management ===== | ||
- | Managing Rheumatoid Arthritis with Dietary Interventions | + | Managing Rheumatoid Arthritis with Dietary Interventions |
==== Pain medications ==== | ==== Pain medications ==== | ||
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===== Evidence of infectious cause ===== | ===== Evidence of infectious cause ===== | ||
- | Scher' | + | Scher' |
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< | < | ||
- | An increasing number of studies are providing support for the view that “autoantibodies” can be generated in response to the persistent presence of a pathogenic microbiota. While high titers of rheumatoid factor (RF) are associated with severe rheumatoid arthritis, they also appear in a number of other diseases including viral, bacterial, and parasitic infections.(({{pubmed> | + | An increasing number of studies are providing support for the view that “autoantibodies” can be generated in response to the persistent presence of a pathogenic microbiota. While high titers of rheumatoid factor (RF) are associated with severe rheumatoid arthritis, they also appear in a number of other diseases including viral, bacterial, and parasitic infections.(({{pmid> |
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==== Development during IRIS ==== | ==== Development during IRIS ==== | ||
- | During | + | During |
- | A number of well-known readily cultured pathogens have been conclusively linked to IRIS: the herpes viruses, cytomegalovirus, | + | A number of well-known readily cultured pathogens have been conclusively linked to IRIS: the herpes viruses, cytomegalovirus, |
- | Interestingly, | + | Interestingly, |
==== Other evidence ==== | ==== Other evidence ==== | ||
- | * **Gut-joint axis** – One excellent example gut–joint axis hypothesis is represented by classic Whipple disease, in which the presence of a single bacterium in the small intestine, // | + | * **Gut-joint axis** – One excellent example gut–joint axis hypothesis is represented by classic Whipple disease, in which the presence of a single bacterium in the small intestine, // |
- | * **Presence of microbes in the synovium** – Several reports have associated RA with bacterial overgrowth and deposition of resultant immune complexes in the synovial fluid.(({{pubmed> | + | * **Presence of microbes in the synovium** – Several reports have associated RA with bacterial overgrowth and deposition of resultant immune complexes in the synovial fluid.(({{pmid> |
- | * **Periodontal disease comorbidity** – Patients with RA often exhibit periodontal disease, which is associated with pathogens like // | + | * **Periodontal disease comorbidity** – Patients with RA often exhibit periodontal disease, which is associated with pathogens like // |
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< | < | ||
- | Consistent with the Marshall Pathogenesis, | + | Consistent with the Marshall Pathogenesis, |
- | 1, | + | 1, |
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< | < | ||
- | Evidence as to how human genes contribute to the development of RA has been weak. Genome-wide associations studies explain only 16% of disease variance.(({{pubmed> | + | Evidence as to how human genes contribute to the development of RA has been weak. Genome-wide associations studies explain only 16% of disease variance.(({{pmid> |
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- | // | + | // |
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- | // | + | // |
===== Data ===== | ===== Data ===== | ||
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sarcoidosis, | sarcoidosis, | ||
- | Read the [[http:// | + | Read the [[https:// |
< | < | ||
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rheumatoid arthritis, dyslexia | rheumatoid arthritis, dyslexia | ||
- | Read the [[http:// | + | Read the [[https:// |
< | < | ||
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===== Childhood ===== | ===== Childhood ===== | ||
- | Do infections trigger juvenile idiopathic arthritis? | + | Do infections trigger juvenile idiopathic arthritis? |
===== Gout ===== | ===== Gout ===== | ||
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I drink about an extra 2.2 L (outside of meals) of water daily and I haven' | I drink about an extra 2.2 L (outside of meals) of water daily and I haven' | ||
- | I recently heard that phytic acid is able to inhibit the enzyme xanthine oxidase that causes a build up of uric acid(({{pubmed> | + | I recently heard that phytic acid is able to inhibit the enzyme xanthine oxidase that causes a build up of uric acid(({{pmid> |
// | // | ||
- | Herein, we report a positive relationship between serum UA and acute-phase reactants, such as high-sensitivity C-reactive protein, fibrinogen, ferritin, complement C3, and erythrocyte sedimentation rate, in a cohort of 2731 nondiabetic adults. The relationship remains significant after adjustment for several confounders, | + | Herein, we report a positive relationship between serum UA and acute-phase reactants, such as high-sensitivity C-reactive protein, fibrinogen, ferritin, complement C3, and erythrocyte sedimentation rate, in a cohort of 2731 nondiabetic adults. The relationship remains significant after adjustment for several confounders, |
- | + | ||
- | The effect of UA was completely blocked by the antioxidant N-acetylcysteine. | + | |
- | (({{pubmed> | + | |
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+ | < | ||
===== Notes and comments ===== | ===== Notes and comments ===== | ||
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If we ever have an article on JIA: | If we ever have an article on JIA: | ||
- | < | + | < |
Aslan M, Kasapcopur O, Yasar H, Polat E, Saribas S, Cakan H, Dirican A, Torun MM, Arısoy N, Kocazeybek B. | Aslan M, Kasapcopur O, Yasar H, Polat E, Saribas S, Cakan H, Dirican A, Torun MM, Arısoy N, Kocazeybek B. | ||
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Rheumatology International, | Rheumatology International, | ||
- | http:// | + | https:// |
Abstract | Abstract | ||
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jejuni come forward and seen common in JIA cases. We also suggest that the pre-diagnosis of microorganisms, | jejuni come forward and seen common in JIA cases. We also suggest that the pre-diagnosis of microorganisms, | ||
- | http:// | + | https:// |
</ | </ | ||
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- | ===== References ===== | + | ===== References =====</ |