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home:diseases:rheumatoid_arthritis [07.14.2019] – [Development during IRIS] sallieq | home:diseases:rheumatoid_arthritis [09.14.2022] (current) – external edit 127.0.0.1 | ||
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=====Management ===== | =====Management ===== | ||
- | Managing Rheumatoid Arthritis with Dietary Interventions | + | Managing Rheumatoid Arthritis with Dietary Interventions |
==== Pain medications ==== | ==== Pain medications ==== | ||
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===== Evidence of infectious cause ===== | ===== Evidence of infectious cause ===== | ||
- | Scher' | + | Scher' |
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< | < | ||
- | An increasing number of studies are providing support for the view that “autoantibodies” can be generated in response to the persistent presence of a pathogenic microbiota. While high titers of rheumatoid factor (RF) are associated with severe rheumatoid arthritis, they also appear in a number of other diseases including viral, bacterial, and parasitic infections.(({{pubmed> | + | An increasing number of studies are providing support for the view that “autoantibodies” can be generated in response to the persistent presence of a pathogenic microbiota. While high titers of rheumatoid factor (RF) are associated with severe rheumatoid arthritis, they also appear in a number of other diseases including viral, bacterial, and parasitic infections.(({{pmid> |
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==== Development during IRIS ==== | ==== Development during IRIS ==== | ||
- | During immune reconstitution inflammatory syndrome, HIV/AIDS patients experience the worsening or onset of systemic inflammatory clinical signs and symptoms following treatment with highly active antiretroviral therapy (HAART). This syndrome results when HAART allows for partial recovery of the immune response. This causes renewed and exuberant host immunological responses towards opportunistic infectious agents, agents that the host accumulated during prior periods of immunosuppression.(({{pubmed> | + | During immune reconstitution inflammatory syndrome, HIV/AIDS patients experience the worsening or onset of systemic inflammatory clinical signs and symptoms following treatment with highly active antiretroviral therapy (HAART). This syndrome results when HAART allows for partial recovery of the immune response. This causes renewed and exuberant host immunological responses towards opportunistic infectious agents, agents that the host accumulated during prior periods of immunosuppression.(({{pmid> |
- | A number of well-known readily cultured pathogens have been conclusively linked to IRIS: the herpes viruses, cytomegalovirus, | + | A number of well-known readily cultured pathogens have been conclusively linked to IRIS: the herpes viruses, cytomegalovirus, |
- | Interestingly, | + | Interestingly, |
==== Other evidence ==== | ==== Other evidence ==== | ||
- | * **Gut-joint axis** – One excellent example gut–joint axis hypothesis is represented by classic Whipple disease, in which the presence of a single bacterium in the small intestine, // | + | * **Gut-joint axis** – One excellent example gut–joint axis hypothesis is represented by classic Whipple disease, in which the presence of a single bacterium in the small intestine, // |
- | * **Presence of microbes in the synovium** – Several reports have associated RA with bacterial overgrowth and deposition of resultant immune complexes in the synovial fluid.(({{pubmed> | + | * **Presence of microbes in the synovium** – Several reports have associated RA with bacterial overgrowth and deposition of resultant immune complexes in the synovial fluid.(({{pmid> |
- | * **Periodontal disease comorbidity** – Patients with RA often exhibit periodontal disease, which is associated with pathogens like // | + | * **Periodontal disease comorbidity** – Patients with RA often exhibit periodontal disease, which is associated with pathogens like // |
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< | < | ||
- | Consistent with the Marshall Pathogenesis, | + | Consistent with the Marshall Pathogenesis, |
- | 1, | + | 1, |
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< | < | ||
- | Evidence as to how human genes contribute to the development of RA has been weak. Genome-wide associations studies explain only 16% of disease variance.(({{pubmed> | + | Evidence as to how human genes contribute to the development of RA has been weak. Genome-wide associations studies explain only 16% of disease variance.(({{pmid> |
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- | // | + | // |
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- | // | + | // |
===== Data ===== | ===== Data ===== | ||
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sarcoidosis, | sarcoidosis, | ||
- | Read the [[http:// | + | Read the [[https:// |
< | < | ||
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rheumatoid arthritis, dyslexia | rheumatoid arthritis, dyslexia | ||
- | Read the [[http:// | + | Read the [[https:// |
< | < | ||
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===== Childhood ===== | ===== Childhood ===== | ||
- | Do infections trigger juvenile idiopathic arthritis? | + | Do infections trigger juvenile idiopathic arthritis? |
===== Gout ===== | ===== Gout ===== | ||
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I drink about an extra 2.2 L (outside of meals) of water daily and I haven' | I drink about an extra 2.2 L (outside of meals) of water daily and I haven' | ||
- | I recently heard that phytic acid is able to inhibit the enzyme xanthine oxidase that causes a build up of uric acid(({{pubmed> | + | I recently heard that phytic acid is able to inhibit the enzyme xanthine oxidase that causes a build up of uric acid(({{pmid> |
// | // | ||
- | Herein, we report a positive relationship between serum UA and acute-phase reactants, such as high-sensitivity C-reactive protein, fibrinogen, ferritin, complement C3, and erythrocyte sedimentation rate, in a cohort of 2731 nondiabetic adults. The relationship remains significant after adjustment for several confounders, | + | Herein, we report a positive relationship between serum UA and acute-phase reactants, such as high-sensitivity C-reactive protein, fibrinogen, ferritin, complement C3, and erythrocyte sedimentation rate, in a cohort of 2731 nondiabetic adults. The relationship remains significant after adjustment for several confounders, |
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+ | < | ||
===== Notes and comments ===== | ===== Notes and comments ===== | ||
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If we ever have an article on JIA: | If we ever have an article on JIA: | ||
- | < | + | < |
Aslan M, Kasapcopur O, Yasar H, Polat E, Saribas S, Cakan H, Dirican A, Torun MM, Arısoy N, Kocazeybek B. | Aslan M, Kasapcopur O, Yasar H, Polat E, Saribas S, Cakan H, Dirican A, Torun MM, Arısoy N, Kocazeybek B. | ||
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Rheumatology International, | Rheumatology International, | ||
- | http:// | + | https:// |
Abstract | Abstract | ||
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jejuni come forward and seen common in JIA cases. We also suggest that the pre-diagnosis of microorganisms, | jejuni come forward and seen common in JIA cases. We also suggest that the pre-diagnosis of microorganisms, | ||
- | http:// | + | https:// |
</ | </ | ||
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- | ===== References ===== | + | ===== References =====</ |