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home:diseases:sarcoidosis [02.28.2019] – [Statistics] sallieqhome:diseases:sarcoidosis [02.28.2019] – [Data] sallieq
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 Kanchwala //et al.// showed that patients with sarcoidosis expressed the antimicrobial peptide cathelicidin less than healthy subjects, and that sicker sarcoidosis patients expressed it least of all.((Kanchwala, A., B. Barna, et al. (2009). [[http://meeting.chestpubs.org/cgi/content/abstract/136/4/127S-a|Deficiencies of cathelicidin and vitamin D accompany disease severity in sarcoidosis]].)) Wiken //et al.// showed that there was a reduced TLR2 mRNA expression in patients with Lofgren's syndrome (a type of acute sarcoidosis).(({{pubmed>long:20813038}})) Note that TLR2 (which the Marshall Pathogenesis theorizes is downregulated in autoimmune disease states) is expressed by the VDR.  Kanchwala //et al.// showed that patients with sarcoidosis expressed the antimicrobial peptide cathelicidin less than healthy subjects, and that sicker sarcoidosis patients expressed it least of all.((Kanchwala, A., B. Barna, et al. (2009). [[http://meeting.chestpubs.org/cgi/content/abstract/136/4/127S-a|Deficiencies of cathelicidin and vitamin D accompany disease severity in sarcoidosis]].)) Wiken //et al.// showed that there was a reduced TLR2 mRNA expression in patients with Lofgren's syndrome (a type of acute sarcoidosis).(({{pubmed>long:20813038}})) Note that TLR2 (which the Marshall Pathogenesis theorizes is downregulated in autoimmune disease states) is expressed by the VDR. 
  
-===== Daata =====+===== Data =====
  
 //from DJ in California//  //from DJ in California// 
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 I tried my best to be unbiased as I was expecting to see about a 20% improvement in health of members, or in other words a 20-25% success rate. I was intending to compare this to the 10% success rate I found done on the use of prednisone to treat Sarcoidosis. That double blind report shows that 10% treated with prednisone achieve remission. (BTW remission in Sarcoidosis as far as I can find out is measured rather subjectively)  I tried my best to be unbiased as I was expecting to see about a 20% improvement in health of members, or in other words a 20-25% success rate. I was intending to compare this to the 10% success rate I found done on the use of prednisone to treat Sarcoidosis. That double blind report shows that 10% treated with prednisone achieve remission. (BTW remission in Sarcoidosis as far as I can find out is measured rather subjectively) 
 +
 The following information is what I found:  The following information is what I found: 
 +
 Sarcoidosis: 236 members; 179 success; 25 no success; 32 unsure  Sarcoidosis: 236 members; 179 success; 25 no success; 32 unsure 
  
home/diseases/sarcoidosis.txt · Last modified: 09.14.2022 by 127.0.0.1
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