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home:diseases:sjogrens [01.02.2019] – [Recent Research] sallieq | home:diseases:sjogrens [01.11.2019] – [Introduction] sallieq | ||
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======Sjogren' | ======Sjogren' | ||
===== Introduction ===== | ===== Introduction ===== | ||
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International classification criteria for Sjögrens syndrome include ocular symptoms, oral symptoms, ocular signs, histopathology, | International classification criteria for Sjögrens syndrome include ocular symptoms, oral symptoms, ocular signs, histopathology, | ||
- | + | Neurologic disease is a common extraglandular manifestation of Sjögren' | |
===== Evidence of infectious cause ===== | ===== Evidence of infectious cause ===== | ||
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+ | ===== Recent Research ===== | ||
+ | According to literature, Sjogren' | ||
- | ===== Patient interviews | + | These results showed that IL-6 stimulation induced REG Iα transcription through STAT3 activation and binding to the consensus sequence of REG Iα promoter in salivary ductal cells. This IL-6/STAT dependent REG Iα induction might play a role in the pathogenesis of SS.(({{pubmed> |
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+ | pSS patients have impaired blood pressure response to standing. Dysautonomia correlates with PSS-associated symptoms and quality of life. | ||
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+ | This information aids understanding of the history and development of dry eye research, in addition to the impact and characteristics of the contributors to the field. | ||
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+ | The purpose of this study was to investigate salivary tissue assessment with various sonoelastographic modalities (real-time tissue elastography, | ||
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+ | Primary Sjögren' | ||
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+ | Abnormalities of memory B cells seem to be closely involved in the pathogenesis of primary Sjögrens Syndrome (pSS) and its malignant complication, | ||
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+ | The presence of Sjögren' | ||
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+ | This report presents a patient with Devics neuromyelitis optica associated with primary Sjögrens syndrome. Her first attack was right-sided optic neuritis at age 10 years. Attacks involving both optic nerves and medulla spinalis were recorded during the ensuing years. The diagnosis of Sjögrens syndrome could not be made until the second decade because it was not suspected. | ||
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+ | The quality of life of patients with Sjogrens syndrome often is degraded further by serious, multisystemic manifestations, | ||
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+ | OBJECTIVES: To develop a questionnaire for the assessment of health-related quality of life (HRQL) in primary Sjögren' | ||
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+ | ===== Patient interviews | ||
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<div class=" | <div class=" | ||
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===== Patient experiences and discussion from Study Site topic(s) ===== | ===== Patient experiences and discussion from Study Site topic(s) ===== | ||
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The aOR for those suffering from at least one rheumatologic disease was 1.56 (95% CI: 1.26-1.93), those with two rheumatologic diseases was 1.98 (95% CI: 1.29-3.04), while those with three or more rheumatologic diseases was 7.86 (95% CI: 1.09-56.58). | The aOR for those suffering from at least one rheumatologic disease was 1.56 (95% CI: 1.26-1.93), those with two rheumatologic diseases was 1.98 (95% CI: 1.29-3.04), while those with three or more rheumatologic diseases was 7.86 (95% CI: 1.09-56.58). | ||
- | ===== Recent Research ===== | ||
- | According to literature, Sjogren' | + | {{tag>disease |
- | These results showed that IL-6 stimulation induced REG Iα transcription through STAT3 activation and binding to the consensus sequence of REG Iα promoter in salivary ductal cells. This IL-6/STAT dependent REG Iα induction might play a role in the pathogenesis of SS.(({{pubmed> | ||
+ | ===== Notes and comments ===== | ||
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- | pSS patients have impaired blood pressure response to standing. Dysautonomia correlates with PSS-associated symptoms and quality of life. | ||
- | |||
- | This information aids understanding of the history and development of dry eye research, in addition to the impact and characteristics of the contributors to the field. | ||
- | |||
- | |||
- | Primary Sjögren' | ||
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- | Abnormalities of memory B cells seem to be closely involved in the pathogenesis of primary Sjögrens Syndrome (pSS) and its malignant complication, | ||
- | |||
- | The presence of Sjögren' | ||
- | |||
- | |||
- | This report presents a patient with Devics neuromyelitis optica associated with primary Sjögrens syndrome. Her first attack was right-sided optic neuritis at age 10 years. Attacks involving both optic nerves and medulla spinalis were recorded during the ensuing years. The diagnosis of Sjögrens syndrome could not be made until the second decade because it was not suspected. | ||
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- | The quality of life of patients with Sjogrens syndrome often is degraded further by serious, multisystemic manifestations, | ||
- | | ||
- | OBJECTIVES: To develop a questionnaire for the assessment of health-related quality of life (HRQL) in primary Sjögren' | ||
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- | {{tag> | ||
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- | ===== Notes and comments ===== | ||
< | < | ||
- | GETCONTENT | + | GETCONTENT |