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home:diseases:sjogrens [01.11.2019] – [Recent Research] sallieqhome:diseases:sjogrens [01.11.2019] – [Recent Research] sallieq
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 International classification criteria for Sjögrens syndrome include ocular symptoms, oral symptoms, ocular signs, histopathology, salivary gland involvement and sialography. The classification requires four of the six items, one of which must be positive minor salivary gland biopsy or a positive antibody test. Early diagnosis is important to prevent further complications.   (({{pubmed>long:25878484}}))   International classification criteria for Sjögrens syndrome include ocular symptoms, oral symptoms, ocular signs, histopathology, salivary gland involvement and sialography. The classification requires four of the six items, one of which must be positive minor salivary gland biopsy or a positive antibody test. Early diagnosis is important to prevent further complications.   (({{pubmed>long:25878484}}))  
  
-Neurologic disease is a common extraglandular manifestation of Sjögren's syndrome  (({{pubmed>long:30627507}})) + 
 +Primary Sjögren's syndrome (pSS) is a chronic systemic autoimmune disease, of slow progression, characterized by lymphocytic infiltration of the exocrine glands, that leads to sicca symptoms, mainly xerophtalmia and xerostomia. It may involve any organ and lead to extraglandular manifestations, which also can precede typical glandular manifestations and delay the diagnosis of pSS. In the past years, better knowledge of the disease has led to improvement in treatment management.  (({{pubmed>long:21794757}}))  
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 ===== Evidence of infectious cause ===== ===== Evidence of infectious cause =====
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 pSS patients have impaired blood pressure response to standing. Dysautonomia correlates with PSS-associated symptoms and quality of life.   (({{pubmed>long:22976617}}))   pSS patients have impaired blood pressure response to standing. Dysautonomia correlates with PSS-associated symptoms and quality of life.   (({{pubmed>long:22976617}}))  
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 +Neurologic disease is a common extraglandular manifestation of Sjögren's syndrome  (({{pubmed>long:30627507}})) 
  
 This information aids understanding of the history and development of dry eye research, in addition to the impact and characteristics of the contributors to the field.  (({{pubmed>long:23321358}}))   This information aids understanding of the history and development of dry eye research, in addition to the impact and characteristics of the contributors to the field.  (({{pubmed>long:23321358}}))  
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