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home:food:aim_health [07.21.2019] – [Zinc] sallieqhome:food:aim_health [07.21.2019] – [Zinc] sallieq
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 ==== Minerals ==== ==== Minerals ====
  
-Some trace elements are altered with chronic kidney disease. Selenium, zinc, and manganese tend to be wasted, and there is growing evidence that selenium deficiency is associated with mortality on dialysis. Other trace elements accumulate, such as chromium, cobalt, lead, molybdenum, and vanadium.(({{pubmed>long:31296778}})) +Some trace elements are altered with chronic kidney disease. Selenium, zinc, and manganese tend to be wasted, and there is growing evidence that selenium deficiency is associated with mortality on dialysis. Other trace elements accumulate, such as chromium, cobalt, lead, molybdenum, and vanadium.(({{pubmed>long:31296778}})) 
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 +Three main areas of research have been identified (//in chronic heart failure//): 1) magnesium, electrolytes and CHF; 2) the transcriptional and antioxidant effects of zinc, selenium, copper; 3) iron-deficiency anemia and CHF.(({{pubmed>long:31242838}})) 
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 +(({{pubmed>long:88888888}})) 
  
 === Zinc === === Zinc ===
  
-Zinc is an essential trace element that is crucial for growth, development, and the maintenance of immune function. Its influence reaches all organs and cell types, representing an integral component of approximately 10% of the human proteome, and encompassing hundreds of key enzymes and transcription factors. Zinc deficiency is strikingly common, affecting up to a quarter of the population in developing countries, but also affecting distinct populations in the developed world as a result of lifestyle, age, and disease-mediated factors. (({{pubmed>long:31305906}}))+Zinc is an essential trace element that is crucial for growth, development, and the maintenance of immune function. Its influence reaches all organs and cell types, representing an integral component of approximately 10% of the human proteome, and encompassing hundreds of key enzymes and transcription factors.  Zinc deficiency is strikingly common, affecting up to a quarter of the population in developing countries, but also affecting distinct populations in the developed world as a result of lifestyle, age, and disease-mediated factors. (({{pubmed>long:31305906}}))
  
 By modulating anti-inflammatory and antioxidant pathways, zinc supplementation is recommended for the treatment of several ailments, such as liver disease, male hypogonadism, cancers, heart disease (e.g. dyslipidemia) and central nervous system disorders; however, the topic of dietary vs. pharmacological doses of zinc remains controversial.(({{pubmed>long:31303527}})) By modulating anti-inflammatory and antioxidant pathways, zinc supplementation is recommended for the treatment of several ailments, such as liver disease, male hypogonadism, cancers, heart disease (e.g. dyslipidemia) and central nervous system disorders; however, the topic of dietary vs. pharmacological doses of zinc remains controversial.(({{pubmed>long:31303527}}))
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 === Ca/Mg ratio === === Ca/Mg ratio ===
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 +Ca/Mg ratio imbalance is associated with prostatic hyperplasia(({{pubmed>long:    28284204}}))
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 + Ca:Mg rose from largely below 3.0 in 1994-5 to generally above or approaching 3.0 after 2000, coinciding with a sharp 2% rise in type 2 diabetes incidence and prevalence in the USA population and a 1994-2005 rise in colorectal cancer incidence among young white, non-Hispanic adult men and women in the USA.(({{pubmed>long:21233058}}))
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 + findings suggested that increased Mg and decreased Ca and Ca/Mg in whole blood were correlated with metabolic syndrome in Chinese adults.(({{pubmed>long:27750224}}))
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 (({{pubmed>long:88888888}})) (({{pubmed>long:88888888}}))
  
-== Selenium (trace element) ==+=== Selenium (trace element) === 
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 +Association of Selenium (Se) deficiency, an essential trace element, has been found with human diseases.(({{pubmed>long:31223567}})) 
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 +Review of recent progress in large-scale and systematic analyses of the relationship between selenium status or selenoproteins and several complex diseases, mainly including population-based cohort studies and meta-analyses, genetic association studies, and some other omics-based studies. Advances in ionomics and its application in studying the interaction between selenium and other trace elements in human health and diseases are also discussed.(({{pubmed>long:31236815}})) 
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 +Expression of some genes is changed with selenium deficiency. Consequently, growth and proliferation of cells, their movement, development, death, and survival, as well as the interaction between cells, the redox regulation of intracellular signaling cascades of inflammation and apoptosis, depend on the selenium status of the body.
  
 +Organic selenium compounds have a high bioavailability and, depending on their concentration, can act both as selenium donors to prevent selenium deficiency and as antitumor drugs due to their toxicity and participation in the regulation of signaling pathways of apoptosis. (({{pubmed>long:    31258141}}))
  
 (({{pubmed>long:88888888}})) (({{pubmed>long:88888888}}))
home/food/aim_health.txt · Last modified: 09.14.2022 by 127.0.0.1
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