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--- home:food:aim_health [07.21.2019]
sallieq [Zinc]
+++ home:food:aim_health [07.22.2019] (current)
sallieq
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   * **salt avoidance** – not recommended given that the body seems to naturally regulate sodium levels independently. Salt is also critical for kidney health. Sodium is used by the kidneys to excrete potassium. (({{pubmed>long:19833911}})) (for more see the //Times// article [[http://www.nytimes.com/2012/06/03/opinion/sunday/we-only-think-we-know-the-truth-about-salt.html|Salt, we misjudged you]]
   * **nutritional supplements** - not recommended. Unless doctor has scientifically established that a particular patient has a digestive problem with absorbing a particular nutrient normally obtained from food, those widely advertised 'nutritional' supplements are a complete waste of money and only improve the revenue of manufacturing companies. [[https://www.thesun.co.uk/news/9398518/over-50s-who-buy-fish-oil-supplements-to-boost-brains-are-wasting-their-money/|experts have provided evidence fish supplements don't work]]
-==== Minerals ====
-Some trace elements are altered with chronic kidney disease. Selenium, zinc, and manganese tend to be wasted, and there is growing evidence that selenium deficiency is associated with mortality on dialysis. Other trace elements accumulate, such as chromium, cobalt, lead, molybdenum, and vanadium.(({{pubmed>long:31296778}}))
-Three main areas of research have been identified (//in chronic heart failure//): 1) magnesium, electrolytes and CHF; 2) the transcriptional and antioxidant effects of zinc, selenium, copper; 3) iron-deficiency anemia and CHF.(({{pubmed>long:31242838}}))
-(({{pubmed>long:88888888}}))
-=== Zinc ===
-Zinc is an essential trace element that is crucial for growth, development, and the maintenance of immune function. Its influence reaches all organs and cell types, representing an integral component of approximately 10% of the human proteome, and encompassing hundreds of key enzymes and transcription factors.  Zinc deficiency is strikingly common, affecting up to a quarter of the population in developing countries, but also affecting distinct populations in the developed world as a result of lifestyle, age, and disease-mediated factors. (({{pubmed>long:31305906}}))
-By modulating anti-inflammatory and antioxidant pathways, zinc supplementation is recommended for the treatment of several ailments, such as liver disease, male hypogonadism, cancers, heart disease (e.g. dyslipidemia) and central nervous system disorders; however, the topic of dietary vs. pharmacological doses of zinc remains controversial.(({{pubmed>long:31303527}}))
-Our results suggest that zinc deficiency is associated with the presence of prehypertension in apparently healthy subjects.(({{pubmed>long:    31262235}}))
-=== Ca/Mg ratio ===
-Ca/Mg ratio imbalance is associated with prostatic hyperplasia(({{pubmed>long:    28284204}}))
- Ca:Mg rose from largely below 3.0 in 1994-5 to generally above or approaching 3.0 after 2000, coinciding with a sharp 2% rise in type 2 diabetes incidence and prevalence in the USA population and a 1994-2005 rise in colorectal cancer incidence among young white, non-Hispanic adult men and women in the USA.(({{pubmed>long:21233058}}))
- findings suggested that increased Mg and decreased Ca and Ca/Mg in whole blood were correlated with metabolic syndrome in Chinese adults.(({{pubmed>long:27750224}}))
-(({{pubmed>long:88888888}}))
-=== Selenium (trace element) ===
-Association of Selenium (Se) deficiency, an essential trace element, has been found with human diseases.(({{pubmed>long:31223567}}))
-Review of recent progress in large-scale and systematic analyses of the relationship between selenium status or selenoproteins and several complex diseases, mainly including population-based cohort studies and meta-analyses, genetic association studies, and some other omics-based studies. Advances in ionomics and its application in studying the interaction between selenium and other trace elements in human health and diseases are also discussed.(({{pubmed>long:31236815}}))
-Expression of some genes is changed with selenium deficiency. Consequently, growth and proliferation of cells, their movement, development, death, and survival, as well as the interaction between cells, the redox regulation of intracellular signaling cascades of inflammation and apoptosis, depend on the selenium status of the body.
-Organic selenium compounds have a high bioavailability and, depending on their concentration, can act both as selenium donors to prevent selenium deficiency and as antitumor drugs due to their toxicity and participation in the regulation of signaling pathways of apoptosis. (({{pubmed>long:    31258141}}))
-(({{pubmed>long:88888888}}))
-=== Boron (trace element) ===
- Via its effect on steroid hormones and interaction with mineral metabolism, boron may be involved in a number of clinical conditions such as arthritis.  (({{pubmed>long:8140253}}))
-Experiments with boron supplementation or deprivation show that boron is involved in calcium and bone metabolism, and its effects are more marked when other nutrients (cholecalciferol, magnesium) are deficient. Boron supplementation increases the serum concentration of 17 beta-estradiol and testosterone but boron excess has toxic effects on reproductive function. Boron may be involved in cerebral function via its effects on the transport across membranes. It affects the synthesis of the extracellular matrix and is beneficial in wound healing.
-Usual dietary boron consumption in humans is 1-2 mg/day for adults.
- Boronated compounds have been shown to be potent anti-osteoporotic, anti-inflammatory, hypolipemic, anti-coagulant and anti-neoplastic agents both in vitro and in vivo in animals.(({{pubmed>long:9638606}}))
-<blockquote>In reality the average intake in developed countries is 1-2 mg of boron per day. Institutionalized patients may receive only 0.25 mg of daily boron. Chemical fertilizers inhibit the uptake of boron from the soil: an organic apple grown in good soil may have 20 mg boron, but if grown with fertilizer it may have only 1 mg of boron. Fertilizers combined with poor food choices have greatly reduced our boron intake compared to 50 or 100 years ago.
-Further, unhealthy cooking methods greatly reduce the availability of boron from food. The cooking water of vegetables containing most of the minerals may be discarded during home cooking or commercial processing; phytic acid in baked goods, cereals and cooked legumes may greatly reduce availability, while gluten sensitivity and Candida overgrowth inhibit the absorption of minerals. All this makes health problems due to boron deficiency now very common.
-</blockquote>  [[https://www.educate-yourself.org/cn/boraxconspiracy03jul12.shtml|Educate yourself by Walter Last July 2912]]

home/food/aim_health.txt · Last modified: 07.22.2019 by sallieq